Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
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Cognigram was piloted in the Emergency Department, Family Medicine, and Geriatric Psychiatry clinics: 58 adults (23 men, 35 women), 67.9 ± 9.8 years (range 43-91), completed the Cognigram and 5-item liking survey.
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Of the 38 patients recruited, 10 (26.3%) met criteria for anosognosia.
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Highly educated at-risk subjects had better cognition and higher grey matter volume at baseline; moreover, higher educational attainment was associated with slower loss of grey matter over time in mutation carriers.
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50/100
The intervention showed no effect on follow-up SUVRs in a covariance analysis with group allocation, baseline intervention SUVR, age, sex, and baseline Mini-Mental State Examination as predictors.
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The prevalence of mild cognitive impairment (MCI) increases among elderly people and is associated with a high risk of dementia.
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This work suggests that academic and community factors beyond years of education have a marked impact on late-life cognition.
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Accurate and early diagnosis of Alzheimer's disease (AD) plays important role for patient care and development of future treatment.
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50/100
In a convenience sample of deceased football players who donated their brains for research, a high proportion had neuropathological evidence of CTE, suggesting that CTE may be related to prior participation in football.
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Callosal AFD was lower in patients compared to controls.
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Repeated smartphone-assisted cognitive testing is feasible with reasonable adherence and moderate relative validity for the Stroop and the Trail Making tests compared with conventional neuropsychological tests.
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Middle-aged adults at risk of dementia show evidence of poorer cognitive performance, principally in visuospatial functions.
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While computerised tomography (CT) may have been the first imaging tool to study human brain, it has not yet been implemented into clinical decision making process for diagnosis of Alzheimer's disease (AD).
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Higher scores on the appetite and weight loss symptom factor were associated with an increased hazard of both AD and non-AD dementia.
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Idiopathic rapid eye movement sleep behaviour disorder is characterized by nocturnal violence, increased muscle tone during rapid eye movement sleep and the lack of any other neurological disease.
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In multivariate voxel-by-voxel analyses, adherence to the MeDi was significantly associated with preserved white matter microstructure in extensive areas, a gain in structural connectivity that was related to strong cognitive benefits.
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In contrast to informal clinical evaluations of oculomotor dysfunction frequency (previous studies: 38%, current clinical examination: 33%), detailed eyetracking investigations revealed eye movement abnormalities in 80% of patients with posterior cortical atrophy (compared to 17% typical Alzheimer's disease, 5% controls).
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Studies supporting the notion that physical activity and exercise can help alleviate the negative impact of age on the body and the mind abound.
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In this review we summarize the epidemiological, cross-sectional, and interventional studies examining the association between physical activity and brain volume, function, and risk for Alzheimer's disease.
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Amyloid deposition is associated with lower cognitive performance both in AD patients and in the normal elderly, but the association is modified by CR, suggesting that CR may be protective against amyloid-related cognitive impairment.
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50/100
Given the uncertain relationship between objective and subjective memory complaints (SMC), we conducted a study of cognitive function in older people with memory complaints in a large population-based elderly Spanish cohort (NEDICES).
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The participants comprising the AIBL cohort represent a group of highly motivated and well-characterized individuals who represent a unique resource for the study of AD.
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The findings support the idea that gait and balance assessment may augment the diagnostic evaluation of dementia.
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Neurodegeneration in Parkinson's disease dementia (PDD) and dementia with Lewy bodies (DLB) affect cortical and subcortical networks involved in saccade generation.
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Both variants of FTD showed significant increases in rates of elation, disinhibition, and aberrant motor behavior compared with AD.
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After exclusion of the participants who had subsequently refused the medical interview, the 3C Study sample consisted of 3,649 men (39.3%) and 5,645 women, mean age 74.4 years, with a relatively high level of education and income.
From across this topic
10 of the 1,533 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Validation of the Remote Automated ki:e Speech Biomarker for Cognition in Mild Cognitive Impairment: Verification and Validation following DiME V3 Framework
- Can modifiable dementia risk factors help account for the predictive link between personality and midlife cognitive health? Evidence from a 17-year longitudinal study of Mexican-origin adults
- A digital biomarker of white-matter routing from diffusion MRI as an early biomarker of Alzheimer’s disease
- Multidomain lifestyle interventions for the risk reduction of cognitive impairment and dementia: A systematic review and meta-analysis
- Chronology and Chronicity of Altered Resting-State Functional Connectivity after Traumatic Brain Injury
- Limbic Vulnerability Characterises REM Sleep Behaviour Disorder Across Prodromal and Established Lewy Body Disease
- Blood biomarkers for dementia in Hispanic and non-Hispanic White adults
- Age at surgical menopause influences cognitive decline and Alzheimer pathology in older women
- Impact of a multidomain lifestyle intervention on regional spontaneous brain activity
- White matter damage in Alzheimer's disease assessed in vivo using diffusion tensor magnetic resonance imaging