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  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
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In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.

Highest usefulness score first. Studies without a score come last.

  1. Loss of connectivity in Alzheimer's disease: an evaluation of white matter tract integrity with colour coded MR diffusion tensor imaging

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Journal of neurology, neurosurgery, and psychiatry 2000-10-01 Brain scans and imaging

    A novel MRI method--diffusion tensor imaging--was used to compare the integrity of several white matter fibre tracts in patients with probable Alzheimer's disease.

  2. Incidence of and risk factors for hallucinations and delusions in patients with probable AD

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Neurology 2000-05-01 Digital health tools

    The authors found a relatively high incidence of hallucinations and delusions in patients diagnosed with probable AD and suggest that specific neurologic signs, cognitive abilities, and accelerated decline may be predictive markers for their occurrence.

  3. Education and other measures of socioeconomic status and risk of incident Alzheimer disease in a defined population of older persons

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Archives of neurology 1997-11-01 Disparities

    Markers of lower socioeconomic status predict risk of developing incident AD.

  4. Speech Characteristics of Patients with Parkinson’s Disease: I. Intensity, Pitch, and Duration

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Journal of Speech and Hearing Disorders 1963-08-01 Digital health tools

    Pfordresher, Mario Liotti and Steven Brown Journal of Parkinson's Disease5:3 (517-524)Quantitative Analysis of Voice in Parkinson Disease Compared to Motor Performance: A Pilot StudyAlice K. Goberman Journal of Speech, Language, and Hearing Research53:4 (836-849)1 Aug 2010Intonation Contrast in Cantonese Speakers With Hypokinetic Dysarthria Associated With Parkinson's DiseaseJoan K.-Y. M. and William in Geriatric Dec of Speech and Voice Associated with Parkinson's Olson Ramig Clinical Linguistics & Jan speech in Parkinson's disease: A M.

  5. Long-term cognitive impairment after critical illness

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. The New England journal of medicine 2013-10-01 Risk factors

    Patients in medical and surgical ICUs are at high risk for long-term cognitive impairment.

  6. Sleep and Neurodegeneration

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Continuum (Minneapolis, Minn.) 2026-08-03 Risk factors

    Sleep apnea is associated with an increased risk of Parkinson disease.

  7. Machine learning-based estimation of the mild cognitive impairment stage using multimodal physical and behavioral measures

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Scientific reports 2025-10-09 Cognitive tests and assessment

    Mild cognitive impairment (MCI) is a prodromal stage of dementia, and its early detection is critical for improving clinical outcomes.

  8. Insomnia Phenotypes, Cardiovascular Risk and Their Link to Brain Health

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Circulation research 2025-08-14 Risk factors

    About 30% to 40% of the general population experiences insomnia symptoms of difficulty initiating or maintaining sleep, and another 10% to 15% of the general population experiences chronic insomnia disorder.

  9. Cognition-Eye-Brain Connection in Alzheimer's Disease Spectrum Revealed by Multimodal Imaging

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Journal of magnetic resonance imaging : JMRI 2025-06-29 Brain scans and imaging

    Reductions of FALFF in temporal regions, especially the left superior temporal gyrus (STG) in MCI patients, were linked to decreased RNFL thickness and increased FAZ area significantly.

  10. A data-driven, multi-domain brain gray matter signature as a powerful biomarker associated with several clinical outcomes

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Alzheimer's & dementia (Amsterdam, Netherlands) 2024-11-23 Prevention trials

    In a separate validation set, the Union Signature demonstrates clinically relevant properties.

  11. Assessment of sensory impairment in older adults with dementia

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Journal of otology 2024-11-15 Risk factors

    Patients with dementia had significantly worse hearing at almost all frequencies tested and significantly greater olfactory impairment than cognitively normal controls.

  12. Alterations of the pulvinar in posterior cortical atrophy: A multimodal MRI study

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Cortex; a journal devoted to the study of the nervous system and behavior 2024-10-19 Brain scans and imaging

    Cognitive and visual functions including visuospatial processing, visual perception, episodic memory, and naming were impaired among PCA patients.

  13. Social isolation and social cognition: A cross-sectional analysis

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Journal of Alzheimer's disease : JAD 2024-10-17 Risk factors

    No significant association was found between social isolation and ToM abilities for both the unadjusted and adjusted models.

  14. Plasma markers of neurodegeneration, latent cognitive abilities and physical activity in healthy aging

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Scientific reports 2024-09-17 Biomarkers

    Blood-based biomarkers of neurodegeneration demonstrate great promise for the diagnosis and prognosis of Alzheimer's disease.

  15. Cognition and Activity of Daily Living Function in people with Parkinson's disease

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Journal of neural transmission (Vienna, Austria : 1996) 2024-07-08 Prevention trials

    The ability to perform activities of daily living (ADL) function is a multifaceted construct that reflects functionality in different daily life situations.

  16. Functional connectivity changes in neurodegenerative biomarker-positive athletes with repeated concussions

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Journal of neurology 2024-04-08 Brain scans and imaging

    Multimodal biomarkers may identify former contact sports athletes with repeated concussions and at risk for dementia.

  17. Preliminary evidence for preserved synaptic density in late-life depression

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Translational psychiatry 2024-03-14 Risk factors

    Late-life depression has been consistently associated with lower gray matter volume, the origin of which remains largely unexplained.

  18. Day-to-day sleep variability with Alzheimer's biomarkers in at-risk elderly

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Alzheimer's & dementia (Amsterdam, Netherlands) 2024-02-16 Biomarkers

    Lower cerebrospinal fluid (CSF) ApoE, higher CSF p-tau181/amyloid-β (Aβ)42, and higher plasma p-tau231/Aβ42 were associated with higher variability of sleep midpoint, sleep duration, and/or activity count.

  19. Validity and Reliability Study of Online Cognitive Tracking Software (BEYNEX)

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Journal of Alzheimer's disease reports 2024-02-06 Cognitive tests and assessment

    Beynex categorization scores showed a moderate agreement with MoCA ratings (weighted Cohen's Kappa = 0.48; 95% CI: 0.38-0.60).

  20. The development and validation of a digital biomarker for remote assessment of Alzheimer's diseases risk

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Digital health 2024-01-23 Cognitive tests and assessment

    ANOVA and Bayesian t-test found no significant differences between the task when it was remotely self-administered by participants at home compared to when it was taken under controlled lab conditions.

  21. Remote and in-clinic digital cognitive screening tools outperform the MoCA to distinguish cerebral amyloid status among cognitively healthy older adults

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Alzheimer's & dementia (Amsterdam, Netherlands) 2023-11-27 Cognitive tests and assessment

    Average performance on the episodic memory (Prices) smartphone task showed the highest accuracy (AUC = 0.77) to distinguish Aβ status.

  22. Sex difference in brain functional connectivity of hippocampus in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. GeroScience 2023-09-25 Brain scans and imaging

    Alzheimer's disease (AD), affecting nearly 6.5 million people, is the fifth leading cause of death in individuals 65 years or older in the USA.

  23. Grey matter volume and CSF biomarkers predict neuropsychological subtypes of MCI

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Neurobiology of aging 2023-07-12 Tau biomarkers

    There is increasing evidence of different subtypes of individuals with mild cognitive impairment (MCI).

  24. AD-BERT: Using pre-trained language model to predict the progression from mild cognitive impairment to Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Journal of biomedical informatics 2023-07-08 Digital health tools

    The use of EHRs for AD-related research is promising, and AD-BERT shows superior predictive performance in modeling MCI-to-AD progression prediction.

  25. Correlations between Cognitive Evaluation and Metabolic Syndrome

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Metabolites 2023-04-17 Risk factors

    One of the most common medical diseases is metabolic syndrome (MetS), which encompasses diabetes and obesity.

From across this topic

10 of the 1,533 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

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