Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.

Highest usefulness score first. Studies without a score come last.

  1. Machine learning in mental health: a scoping review of methods and applications

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Psychological medicine 2019-02-12 Digital health tools

    Overall, the application of ML to mental health has demonstrated a range of benefits across the areas of diagnosis, treatment and support, research, and clinical administration.

  2. Maintenance, reserve and compensation: the cognitive neuroscience of healthy ageing

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Nature reviews. Neuroscience 2018-11-01 Brain scans and imaging

    Cognitive ageing research examines the cognitive abilities that are preserved and/or those that decline with advanced age.

  3. Spatial navigation deficits - overlooked cognitive marker for preclinical Alzheimer disease?

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Nature reviews. Neurology 2018-08-01 Risk factors

    Detection of incipient Alzheimer disease (AD) pathophysiology is critical to identify preclinical individuals and target potentially disease-modifying therapies towards them.

  4. Working definitions, subjective and objective assessments and experimental paradigms in a study exploring social withdrawal in schizophrenia and Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Neuroscience and biobehavioral reviews 2018-06-24 Cognitive tests and assessment

    Social withdrawal is one of the first and common signs of early social dysfunction in a number of important neuropsychiatric disorders, likely because of the enormous amount and complexity of brain processes required to initiate and maintain social relationships (Adolphs, 2009).

  5. Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery-2018

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. British journal of anaesthesia 2018-06-15 Clinical safety

    Cognitive change affecting patients after anaesthesia and surgery has been recognised for more than 100 yr. Research into cognitive change after anaesthesia and surgery accelerated in the 1980s when multiple studies utilised detailed neuropsychological testing for assessment of cognitive change after cardiac surgery.

  6. Alzheimer's Disease: Past, Present, and Future

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Journal of the International Neuropsychological Society : JINS 2017-10-01 Mild cognitive impairment

    Although dementia has been described in ancient texts over many centuries (e.g., "Be kind to your father, even if his mind fail him." - Old Testament: Sirach 3:12), our knowledge of its underlying causes is little more than a century old.

  7. Motor function deficits in the 12 month-old female 5xFAD mouse model of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Behavioural brain research 2017-09-07 Risk factors

    Motor problems occur early in some patients with Alzheimer's disease (AD) and as the disease progresses many patients develop motor dysfunction.

  8. Reduced acoustic startle response and peripheral hearing loss in the 5xFAD mouse model of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Genes, brain, and behavior 2017-03-08 Risk factors

    Hearing dysfunction has been associated with Alzheimer's disease (AD) in humans, but there is little data on the auditory function of mouse models of AD.

  9. Multimodal Neuroimaging Feature Learning With Multimodal Stacked Deep Polynomial Networks for Diagnosis of Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. IEEE journal of biomedical and health informatics 2017-01-19 Digital health tools

    The accurate diagnosis of Alzheimer's disease (AD) and its early stage, i.e., mild cognitive impairment, is essential for timely treatment and possible delay of AD.

  10. The Mild Behavioral Impairment Checklist (MBI-C): A Rating Scale for Neuropsychiatric Symptoms in Pre-Dementia Populations

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Journal of Alzheimer's disease : JAD 2017-01-01 Getting a diagnosis

    The MBI-C provides the first measure specifically developed to assess the MBI construct as explicitly described in the criteria.

  11. Sleep Disturbances in Frontotemporal Dementia

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Current neurology and neuroscience reports 2016-09 Risk factors

    Sleep disorders appear to be frequent comorbidities in patients with frontotemporal dementia (FTD).

  12. Neuroplasticity and Clinical Practice: Building Brain Power for Health

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Frontiers in psychology 2016-07-26 Cognitive tests and assessment

    The focus of this review is on driving neuroplasticity in a positive direction using evidence-based interventions that also have the potential to improve general health.

  13. Self, cortical midline structures and the resting state: Implications for Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Neuroscience and biobehavioral reviews 2016-05-24 Brain scans and imaging

    Different aspects of the self have been reported to be affected in many neurological or psychiatric diseases such as Alzheimer's disease (AD), including mainly higher-level cognitive self-unawareness.

  14. Default mode network differences between rigidity- and tremor-predominant Parkinson's disease

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Cortex; a journal devoted to the study of the nervous system and behavior 2016-05-06 Brain scans and imaging

    There was decreased activity in the left inferior parietal cortex (IPC) and the left posterior cingulate cortex (PCC) within the DMN between PDAR and both HC and PDT subjects, even after controlling for multiple comparisons, but not between PDT and HC.

  15. Single subject prediction of brain disorders in neuroimaging: Promises and pitfalls

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. NeuroImage 2016-03-21 Digital health tools

    Neuroimaging-based single subject prediction of brain disorders has gained increasing attention in recent years.

  16. Hydrogen Proton Magnetic Resonance Spectroscopy in Multidomain Amnestic Mild Cognitive Impairment and Vascular Cognitive Impairment Without Dementia

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. American journal of Alzheimer's disease and other dementias 2016-03-14 Prevention trials

    To investigate the value of hydrogen proton magnet resonance spectroscopy ((1)H-MRS) in the differential diagnosis of multiple-domain amnestic mild cognitive impairment (M-aMCI) and vascular cognitive impairment with no dementia (VCIND); (1)H-MRS was performed in patients with M-aMCI and VCIND.

  17. Preclinical Cerebral Network Connectivity Evidence of Deficits in Mild White Matter Lesions

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Frontiers in aging neuroscience 2016-02-18 Brain scans and imaging

    White matter lesions (WMLs) are notable for their high prevalence and have been demonstrated to be a potential neuroimaging biomarker of early diagnosis of Alzheimer's disease.

  18. Sleep, Cognition and Dementia

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Current psychiatry reports 2015-12 Risk factors

    The older patient population is growing rapidly around the world and in the USA.

  19. Bilingualism, dementia, cognitive and neural reserve

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Current opinion in neurology 2015-12 Risk factors

    We discuss the role of bilingualism as a source of cognitive reserve and we propose the putative neural mechanisms through which lifelong bilingualism leads to a neural reserve that delays the onset of dementia.

  20. Cerebral correlates of cognitive reserve

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Psychiatry research. Neuroimaging 2015-10-19 Risk factors

    Cognitive reserve is a hypothetical concept introduced to explain discrepancies between severity of clinical dementia syndromes and the extent of dementia pathology.

  21. Default mode network connectivity in patients with idiopathic normal pressure hydrocephalus

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Journal of neurosurgery 2015-08-21 Brain scans and imaging

    Both ROI-based and voxel-based analyses revealed reduced DMN connectivity in patients with iNPH.

  22. Cognitive reserve and lifestyle: moving towards preclinical Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Frontiers in aging neuroscience 2015-08-10 Risk factors

    The large majority of neuroimaging studies in Alzheimer's disease (AD) patients have supported the idea that lifestyle factors may protect against the clinical manifestations of AD rather than influence AD neuropathological processes (the cognitive reserve hypothesis).

  23. Aberrant functional connectivity of default-mode network in type 2 diabetes patients

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. European radiology 2015-04-23 Brain scans and imaging

    Patients showed increased connectivity around the medial prefrontal cortex in the anterior sub-network, but decreased connectivity around the posterior cingulate cortex in the posterior sub-network.

  24. Diagnosis and treatment of depression and cognitive impairment in late life

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Annals of the New York Academy of Sciences 2015-02-05 Risk factors

    Cognitive impairment in late-life depression is prevalent, disabling, and heterogeneous.

  25. Effects of metabolic syndrome on language functions in aging

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Journal of the International Neuropsychological Society : JINS 2015-02 Risk factors

    This study explored effects of the metabolic syndrome (MetS) on language in aging.

From across this topic

9 of the 1,533 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 9. The same 9 appear here every time.

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