Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Download bibliography of all 8,032 studies, highest score first: BibTeX (.bib) · RIS (.ris)
Highest usefulness score first. Studies without a score come last.
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In medical school, students learn to view the world through a biomedical lens.
Why it matters
This personal essay describes how the standard mental status exam can miss a person's individuality, illustrated through the author's grandmother who has Alzheimer's disease. It is a reflection on clinical practice and does not test any treatment, cure, or prevention.
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Dementias are expensive diseases: the net annual cost in European healthcare is about € 28.000 per case with a strong stage dependency, of which medical care accounts for about 19%.
Why it matters
This survey of German memory clinics calculated the personnel and procedure costs of diagnosing dementia, including biomarker tests, and found these costs are not fully reimbursed. It is about diagnostic costs, not about treating, curing, or preventing Alzheimer's disease.
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Many National Forest Inventory (NFI) stakeholders would benefit from accurate estimates at finer geographic scales than most currently implemented in operational estimates using NFI sample data.
Why it matters
This study used small area estimation to improve the precision of county-level forest volume estimates in three U.S. states. It provides no information on treating, curing or preventing Alzheimer's disease.
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Predictors of an AD dementia diagnosis included age (odds ratio [OR], 1.71) and use of antipsychotics (OR, 2.50) and hypertension medication (OR, 1.25).
Why it matters
This study found that older age, use of antipsychotics, and use of hypertension medication predicted an Alzheimer's disease dementia diagnosis, while use of anxiolytics, inpatient status at diagnosis, and a history of stroke were possible protective factors. None of these factors differentiated Alzheimer's disease dementia from all-cause dementia.
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32/100
She presented compelling data that showed the vastly improved ease of use and overall satisfaction of nasal glucagon vs its injectable counterpart.
Why it matters
This news piece reports on nasal versus injectable glucagon for severe low blood sugar and on associations between severe hypoglycemia and heart conditions. It contains no information on treating, curing, or preventing Alzheimer's disease.
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OpenStreetMap provides a valuable crowd-sourced database of raw geospatial data for constructing models of urban street networks for scientific analysis.
Why it matters
This project built and shared street network models and measures for locations across the United States. It provides no information on treating, curing or preventing Alzheimer's disease.
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120 patients were included in the audit with a confirmed stroke on CTB/MRI.
Why it matters
In this audit of 120 stroke patients, early cognitive screening helped predict discharge destination and length of stay, with more severe cognitive impairment linked to longer stays and lower likelihood of going home. The findings support using early cognitive screening to plan care after stroke.
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32/100
Care assistants have a unique insight into the lives of service users and those factors which may impede or enhance the delivery of high quality dementia oriented care.
Why it matters
This interview study examines care assistants' experiences of dementia care in British long-term care environments. It offers no information on treating, curing or preventing Alzheimer's disease.
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It is a well established fact that Down Syndrome (DS) individuals have a tendency to develop Alzheimer's disease (AD) (Lott, I.T., Head, E., 2005.
Why it matters
Young people with Down syndrome but without significant Alzheimer's clinical symptoms showed reduced sensitivity to optic flow motion compared with mental age-matched controls, and visual evoked potentials showed no response to optic flow. This is a study of visual motion perception in young adults with Down syndrome, not a test of any treatment, cure, or prevention of Alzheimer's disease.
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fifty-five geriatricians responded. Ninety-one per cent were consultant physicians, and 71% were not involved in outpatient diagnostic services.
Why it matters
In this survey of 55 consultant geriatricians in the UK, most felt that current dementia training was inadequate and wanted more structure, more time on attachments, less geographical variation, and better collaboration with psychiatry. This is about doctor training and confidence in dementia care, not about treating, curing, or preventing the disease.
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In the history of psychiatry, the words mad and psychosis have often been used interchangeably, negatively contributing to the stigma associated with the term and the illness itself.
Why it matters
This paper reviews psychosis in children and youth with a focus on early-onset schizophrenia, noting that very early onset schizophrenia is associated with greater familial vulnerability and a worse prognosis. It also notes that many of these children are mistakenly identified as having a pervasive developmental disorder because of similarities in presentation.
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From 1999 to 2004, the U.S. age-adjusted annual death rate per 100,000 for dementia was 628 in blacks and 647 in whites.
Why it matters
From 1999 to 2004, overall dementia death rates were similar in US Blacks and Whites, but the racial difference varied by region. Blacks were relatively more likely to receive a diagnosis of unspecified dementia or senility than Alzheimer's disease.
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The object of this study was to investigate the attitudes of physicians, nurses and the general public to physician-assisted suicide (PAS), active voluntary euthanasia (AVE) and passive euthanasia (PE) in Finland.
Why it matters
In Finland, passive euthanasia was most often considered acceptable in a scenario of severe dementia, by 88% of physicians, 79% of nurses, and 64% of the general public. This concerns end-of-life attitudes, not the treatment, cure, or prevention of Alzheimer's disease.
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This review discusses the research published in the last five years on the behavioral, genetic, medical, and neuroscience aspects of Down syndrome.
Why it matters
This is a review of research published over five years on the behavioral, genetic, medical, and neuroscience aspects of Down syndrome, with Alzheimer disease among the most active areas. It reports on existing research and does not present a new treatment, cure, or prevention.
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Cognitive processes and their decline with aging were studied in individuals with Down Syndrome (DS) and individuals of comparable mental handicap without Down Syndrome (NonDS).
Why it matters
Some cognitive tests showed poorer performance in people with Down syndrome at and above 40 years, and the authors say these tests hold promise for diagnosing early signs of Alzheimer-type dementia. This is about assessment and diagnosis, not about treating, curing, or preventing the disease.
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31/100
Understanding dementia beliefs among Vietnamese people is crucial for the development of evidence-based interventions to promote positive help-seeking behaviors when facing the risk of dementia for themselves and their relatives.
Why it matters
In this survey of 300 adults in Central Vietnam, perceived dementia threat to oneself was linked to employment status, anxiety about aging, knowing someone with dementia, and dementia knowledge. The perceived importance of advance care planning for dementia was predicted by age, religiosity, dementia knowledge, and perceived threat of dementia to oneself.
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Obstructive sleep apnea (OSA), a prevalent sleep-disordered breathing condition, is increasingly recognized as a modifiable risk factor for cognitive decline and dementia, including Alzheimer’s disease and vascular dementia.
Why it matters
This review describes obstructive sleep apnea as a modifiable risk factor for cognitive decline and dementia and calls for proactive screening and management. It summarizes existing evidence and does not report new trial results showing that treating sleep apnea prevents dementia.
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BackgroundAlzheimer's disease and related dementia (ADRD) affect nearly half of assisted living (AL) residents, the majority of whom have palliative care (PC) needs at the end of life (EOL).
Why it matters
This qualitative study analyzed homework assignments from 17 assisted living staff across six communities in southwest Florida who took part in a palliative care education program. Care planning coordination with family emerged as an overarching theme, with family involvement described across physical, social, emotional, and spiritual care domains.
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Neighborhood disadvantage is a risk factor for dementia, but the mechanisms involved are not well understood.
Why it matters
In 132 older adults without stroke or dementia, greater neighborhood deprivation was linked to lower whole-brain cerebrovascular reactivity, even after adjusting for vascular risk factors and an Alzheimer's blood marker. The authors note that more diverse samples and a life-course approach are needed, and the study does not test any treatment.
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31/100
The model achieved and AUC of 0.72 [0.64, 0.81].
Why it matters
This study used a machine learning model to predict low cognitive ability before symptoms from social factors like worry, neighborhood deprivation, income, and support. It is about predicting risk, not about treating, curing, or preventing Alzheimer's disease.
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31/100
The Mediterranean diet (MedDiet) is among the most extensively studied dietary patterns and has been consistently associated with reduced risk of all-cause mortality, cardiovascular disease, metabolic disorders, cognitive decline and several types of cancers.
Why it matters
This review reports that the Mediterranean diet has been consistently linked to reduced risk of cognitive decline and describes possible mechanisms for its effects. As a review of existing evidence, it does not prove that the diet prevents or treats Alzheimer's disease.
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This Journal is not only a new publication but also the culmination of a shared vision and a timely response to one of the most significant demographic shifts in human history: the rapid aging of the South Asian population.
Why it matters
This editorial introduces a new journal focused on geriatric medicine, surgery, palliative care, and hospice in South Asia, noting that less than 1% of the population receives specialized geriatric care. It is a journal launch announcement and reports no research on treating, curing, or preventing Alzheimer's disease.
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31/100
Caregivers considered telemedicine useful, accessible, and safe, facilitating the continuity of care and strengthening the caregiver–professional relationship.
Why it matters
Caregivers in this study found telemedicine useful, accessible, and safe for dementia care, though they noted the lack of physical examination and occasional technical problems, and most preferred a mix of remote and in-person visits. It addresses care delivery and support, not treating, curing, or preventing the disease.
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Dementia is a progressive neurodegenerative disorder that represents a growing challenge to global health, especially in aging populations.
Why it matters
This review describes how nutritional insufficiency in rural populations may contribute to dementia through gut-brain axis dysfunction, including reduced microbial diversity and increased inflammation. It evaluates nutraceuticals and dietary interventions, but the evidence discussed is preclinical and clinical, not a proven treatment.
From across this topic
10 of the 7,981 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Meta-Analysis of the Effects of Computerized Cognitive Training on Executive Functions: a Cross-Disciplinary Taxonomy for Classifying Outcome Cognitive Factors
- Trajectories of Depressive Symptoms Before Diagnosis of Dementia: A 28-Year Follow-up Study
- Promotors and barriers to the implementation and adoption of assistive technology and telecare for people with dementia and their caregivers: a systematic review of the literature
- Intervention for the Management of Neuropsychiatric Symptoms to Reduce Caregiver Stress: Protocol for the Mindful and Self-Compassion Care Intervention for Caregivers of Persons Living With Dementia
- Automatic dementia screening and scoring by applying deep learning on clock-drawing tests
- Activating Developmental Reserve Capacity Via Cognitive Training or Non-invasive Brain Stimulation: Potentials for Promoting Fronto-Parietal and Hippocampal-Striatal Network Functions in Old Age
- Implementation of Telemedicine for Patients With Dementia and Their Caregivers: Scoping Review
- Safety, Efficacy, and Feasibility of Intranasal Insulin for the Treatment of Mild Cognitive Impairment and Alzheimer Disease Dementia: A Randomized Clinical Trial
- Frontotemporal dementia. How to deal with its diagnostic complexity?
- Impact of home healthcare reform on place of death for people with dementia: A nationwide cohort study accounting for cultural factors of impending death discharge