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Down syndrome: progress in research
Roizen NJ.. Mental retardation and developmental disabilities research reviews, 2001-01-01
Topic: Risk, prevention and care in population studies
This review discusses the research published in the last five years on the behavioral, genetic, medical, and neuroscience aspects of Down syndrome. The subject areas that have experienced the most active research include Alzheimer disease, language development, leukemia, and pregnancy screening and diagnosis. These and other areas are reviewed.
Key findings
- This review discusses the research published in the last five years on the behavioral, genetic, medical, and neuroscience aspects of Down syndrome.
- The subject areas that have experienced the most active research include Alzheimer disease, language development, leukemia, and pregnancy screening and diagnosis.
Why it matters
This is a review of research published over five years on the behavioral, genetic, medical, and neuroscience aspects of Down syndrome, with Alzheimer disease among the most active areas. It reports on existing research and does not present a new treatment, cure, or prevention.
Study details
- Evidence strengthLow
How this study scored 32/100
Published in a peer-reviewed journal. Scored zero for study design, sample size, effect reported, studied in people and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Mental retardation and developmental disabilities research reviews) |
| Journal's citation record | 1 / 4 | Mental Retardation and Developmental Disabilities Research Reviews: journal h-index 120 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 2001 — older than 20 years, still counted |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 3 / 7 | Cited 26 times (OpenAlex, 2026-10-10) |
| Citations per year | 0 / 5 | 1.0 citations a year over 27 year(s) since 2001 |
| Impact for its field and year | 2 / 6 | Cited 2.2× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 0 / 4 | Cited 1 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 2 / 4 | Last-listed author Nancy Roizen: h-index 45 (OpenAlex, whole career) |
| Institution's track record | 2 / 3 | University of Chicago: institution h-index 1,769 (OpenAlex) |
| Multi-centre collaboration | 1 / 3 | OpenAlex lists 3 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 11241881) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 32 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
May need a subscription OpenAlex found no free copy of the full text (checked 6 Feb 1020), so the publisher may charge for it. The PubMed abstract is free.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. Check the citation against the original before you use it.
APA 7th
Roizen, N. J. (2001). Down syndrome: progress in research. Mental retardation and developmental disabilities research reviews. https://doi.org/10.1002/1098-2779(200102)7:1<38::aid-mrdd1006>3.0.co;2-c
Vancouver
Roizen NJ. Down syndrome: progress in research. Mental retardation and developmental disabilities research reviews. 2001. doi:10.1002/1098-2779(200102)7:1<38::aid-mrdd1006>3.0.co;2-c. PMID: 11241881.
BibTeX
@article{roizen2001-11241881,
author = {Roizen, N. J.},
title = {{Down syndrome: progress in research}},
journal = {Mental retardation and developmental disabilities research reviews},
year = {2001},
doi = {10.1002/1098-2779(200102)7:1<38::aid-mrdd1006>3.0.co;2-c},
pmid = {11241881},
url = {https://doi.org/10.1002/1098-2779(200102)7:1<38::aid-mrdd1006>3.0.co;2-c}
}
Studies this one cites
Referenced by this study and also in the alzhub library, so you can read them here.