Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
-
36/100
Disaster risk reduction efforts in the education sector not only create a safer environment but also encourage sustainable development.
Why it matters
This review is about disaster risk reduction education and contains no information on Alzheimer's disease treatment, cure, or prevention.
-
Data from both pilot studies are reported including item analysis and quantitative and qualitative results.
Why it matters
This article reports on the development and pilot testing of two new measures of positive psychosocial outcomes for people living with dementia. The measures are still developing and warrant further testing, and the study does not evaluate any treatment, cure, or prevention.
-
The study found significant correlations between caregiver competence, QoL, and burden/stress with the QoL of individuals with dementia.
Why it matters
This cross-sectional study found that caregiver competence, quality of life, burden, and executive function were significantly associated with the quality of life of people with mild and moderate dementia. It concerns caregiver factors and disease management, not treating, curing, or preventing Alzheimer's disease.
-
36/100
Dementia cases are projected to triple globally by 2050, largely driven by an aging population.
Why it matters
This ecological study found a positive association between total meat supply and dementia incidence across 204 countries, with a stronger effect in low- and middle-income countries. It identifies meat supply as a possible modifiable dietary factor, but the design cannot establish cause and effect.
-
An integrated TCD-NIRS protocol was feasible in these patient groups to measure NVC, but less-so in delirium.
Why it matters
This small feasibility study used ultrasound and near-infrared spectroscopy to measure brain blood flow responses in people with dementia, delirium, depression and healthy controls. It tested whether the method works, not whether it treats or prevents Alzheimer's disease.
-
A longstanding body of public enquiries and research identifies people living with dementia experience systemic inequalities within hospital settings, concluding a focus on improving care cultures is required.
Why it matters
This hospital ethnography examined how ethnicity, gender and social class affect the everyday care of people with dementia on NHS acute wards. It found that these intersecting factors influenced who was allowed to walk freely and who faced tighter ward rules, with institutional racism and attitudes to ageing shaping routine care.
-
Cerebral small vessel disease (CSVD) is a common disease in older people, characterized by damage to intracranial microvessels, leading to cognitive decline, increased risk of stroke, and dementia.
Why it matters
This review covers current and emerging therapeutic strategies for cerebral small vessel disease, including pharmacological, immune-related, and genetic approaches, along with lifestyle modifications. It emphasizes that more clinical trials are needed to validate these treatments, so no therapy is established for treating, curing, or preventing Alzheimer's disease.
-
In adjusted analyses, low vs. high livability was associated with higher dementia prevalence (B=0.38; p-value=0.31).
Why it matters
This exploratory county-level study found that lower community livability was linked to higher dementia prevalence, but the result was not statistically significant. It is an early, exploratory analysis and does not test any treatment, cure or prevention.
-
These preliminary findings reveal white matter alterations associated with consensus MCI diagnosis and to socioeconomic differences in a clinical cohort of rural‐dwelling older adults.
Why it matters
In a rural aging cohort, both a diagnosis of mild cognitive impairment and greater neighborhood disadvantage predicted differences in white matter microstructure on brain scans. The authors describe these as preliminary findings, and the study does not test any treatment or prevention.
-
Our findings suggest differences in local cortical organization by neighborhood disadvantage, which also mediated the relationship between ADI and cognitive performance, providing a possible network‐based mechanism, explaining risk for cognitive decline and dementia associated with disadvantaged neighborhoods.
Why it matters
This study found that people in more disadvantaged neighborhoods had worse cognitive test scores, and suggested differences in brain organization may explain the link. It does not test any treatment, cure, or prevention.
-
Our findings suggest differences in local cortical organization by neighborhood disadvantage, which also mediated the relationship between ADI and cognitive performance, providing a possible network‐based mechanism, explaining risk for cognitive decline and dementia associated with disadvantaged neighborhoods.
Why it matters
This study found that people in more disadvantaged neighborhoods had worse cognitive test scores, and suggested differences in brain organization may explain the link. It does not test any treatment, cure, or prevention.
-
Accessibility to food stores offering nutritious and affordable options is critical to ensure urban residents lead healthy lives.
Why it matters
This study measured food access equity by factoring grocery store pricing into spatial accessibility measures and found walking to be more inequitable than driving. It has no relevance to treating, curing, or preventing Alzheimer's disease.
-
Enrollment in Medicare Advantage (MA) has been rapidly growing.
Why it matters
This study found that Medicare Advantage enrollment was not associated with days spent at home, nursing home days, likelihood of becoming a long-stay resident, hospital days, hospital readmission, or 1-year mortality. There was a modest increase in successful discharge to the community associated with a 10-percentage-point increase in Medicare Advantage enrollment.
-
This study aimed to evaluate the impact of the policy to reduce the reimbursement fee for percutaneous endoscopic gastrostomy (PEG) on the number of PEG procedures performed among older adults with dementia.
Why it matters
This study found that a Japanese policy reducing reimbursement for gastrostomy feeding tubes had remarkably minimal impact on how often the procedure was performed in older adults with dementia. It is about healthcare payment policy and feeding tube use, not about treating, curing, or preventing Alzheimer's disease itself.
-
Lower diagnosed dementia rates in MA compared to TM may exacerbate racial/ethnic disparities in diagnosed dementia.
Why it matters
This study estimated that diagnosed dementia prevalence and incidence were lower in Medicare Advantage than in traditional Medicare. It does not test any treatment, cure, or prevention, and it suggests these lower rates may exacerbate racial and ethnic disparities in diagnosed dementia.
-
Medicaid-funded long-term services and supports (LTSS) are foundational in helping older dual-enrollees with disabilities remain in the community.
Why it matters
This study describes characteristics of older adults with disabilities or probable dementia who are enrolled in both Medicare and Medicaid, and where they live. It does not test any treatment, cure, or prevention for Alzheimer's disease.
-
This cross-sectional study examines the characteristics of prior authorization policies for new drugs in Medicare Part D to understand whether they are consistent with US Food and Drug Administration indications.
Why it matters
This cross-sectional study examines the characteristics of prior authorization policies for new drugs in Medicare Part D and whether they are consistent with FDA indications. It contains no research findings on treating, curing, or preventing Alzheimer's disease.
-
Marginal utility of financial resources when needing long-term care, and the related incentives for precautionary savings and insurance, may vary significantly by whether one receives care at home or in a nursing home.
Why it matters
This economic analysis found that the marginal utility of financial resources is significantly higher when care is received at home rather than in a nursing home. This implies stronger incentives to save for those expecting home care and a higher value for additional home care subsidies than for nursing home subsidies.
-
Dispositional inward anger expression may increase susceptibility to the detrimental impacts of neighborhood disadvantage on cognitive health.
Why it matters
In 1,314 African Americans, greater neighborhood disadvantage and racial residential segregation were associated with faster rates of 10-year cognitive decline. Among those with high inward anger expression, decline was 33% and 35% faster for neighborhood disadvantage and segregation, respectively.
-
Studies in the neurotypical population have demonstrated that personal social networks can mitigate cognitive decline and the development of Alzheimer disease.
Why it matters
This proof-of-principle study showed that the personal social networks of people with Down syndrome can be measured reliably, with self-reports matching caregiver reports. Because social networks have been linked to less cognitive decline in the neurotypical population, the authors say future work can now test interventions to enhance these networks for preventing Alzheimer's disease.
-
From 2013 to 2019, Medicare Part D beneficiaries 65 years or older received 47.7 million 30-day fills for the treatment of OAB.
Why it matters
This study describes prescribing patterns for overactive bladder in Medicare beneficiaries and found that anticholinergics made up most prescriptions in 2019, with geographic variation. It does not test any treatment, cure or prevention for Alzheimer's disease, though anticholinergic medicines are sometimes discussed in relation to cognition.
-
The three modifications had comparable performance when the number of deaths was large relative to the denominator and the age distribution was as in the standard population.
Why it matters
This study compared statistical methods for calculating confidence intervals for age-adjusted death rates when data are sparse. It is a methods paper and does not address treating, curing, or preventing Alzheimer's disease.
-
Overall, 39 participants participated across the 6 stakeholder focus groups.
Why it matters
This focus group study gathered feedback from 39 stakeholders to help develop a digital platform for dementia home care. It reports no treatment or prevention results, only plans for further development of the platform.
-
Closing the gap substantially reduced individuals' out-of-pocket spending, and the reduction was larger for those with more severe mental disorders.
Why it matters
This study found that closing the Medicare Part D coverage gap increased branded drug use across groups, but the effect was substantially smaller for beneficiaries with Alzheimer's disease and dementia. It suggests that lowering medication costs alone may not be enough to improve adherence for all conditions, including Alzheimer's disease.
-
We found the common trends of increasing spatial patterning of housing prices and all-cause mortality.
Why it matters
This study found that higher neighborhood housing prices were associated with lower all-cause mortality in Seoul, Korea. It provides no information on treating, curing or preventing Alzheimer's disease.
From across this topic
10 of the 7,967 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Abrupt discontinuation and tapering of antipsychotics in older adults with dementia: a target trial emulation study
- Incidence of Alzheimer’s disease (AD) dementia and mild cognitive impairment (MCI) in the United States Medicare population
- Depression and risk of cognitive decline and dementia: Implications and strategies for prevention
- Postmenopausal hormone replacement therapy: scientific review
- Blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive impairment and dementia
- Cholinesterase inhibitor and N-methyl-D-aspartic acid receptor antagonist use in older adults with end-stage dementia: a survey of hospice medical directors
- Accuracy of a panel of 5 cerebrospinal fluid biomarkers in the differential diagnosis of patients with dementia and/or parkinsonian disorders
- Dementia in western Europe: epidemiological evidence and implications for policy making
- Association of Metformin use with risk of dementia in patients with type 2 diabetes: A systematic review and meta-analysis
- Association of a MIND Diet with Brain Structure and Dementia in a French Population