Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
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Older people reaching end-of-life status are particularly at risk of adverse effects of drug therapy.
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Obstructive sleep apnea syndrome (OSAS) is a common disorder with far-reaching health implications.
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Several areas of end-of-life care provision could be improved.
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Recent epidemiological and experimental studies suggest a link between cognitive decline in late adulthood and sports concussions sustained in early adulthood.
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36/100
The elderly are the most rapidly growing population group in the world.
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Today, tens of millions of elderly individuals worldwide suffer from dementia.
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A growing number of structural neuroimaging studies have reported significant changes in gray matter density or volume and white matter microstructure in the adult human brain following training.
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Sleep disturbances are prevalent in patients with Alzheimer' disease (AD), being one of the most troubling symptoms during the progression of disease.
Why it matters
In this small sleep study, people with mild cognitive impairment had shorter REM sleep and more fragmented slow-wave sleep than healthy elders, and the REM reduction was more noticeable in APOE epsilon4 carriers. The findings suggest sleep changes can appear before Alzheimer diagnosis but do not show that treating sleep problems prevents dementia.
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Because previous research favored care in the Netherlands to that in the United States, findings suggest improvement in end-of-life care and outcomes in the United States and stability in the Netherlands.
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We analyze the relationship between age of survival, morbidity, and disability among centenarians (age 100-104 years), semisupercentenarians (age 105-109 years), and supercentenarians (age 110-119 years).
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The caregiving stressor is associated with considerable psychological vulnerability, sleep disorders, and risk of alterations in the cardiovascular system, which seem to be modulated by caregiving characteristics.
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Interest in dementia has increased over the past few decades.
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The hippocampus is known to support recollection memory, but the relation between its structure and recollection in healthy adults has not been established.
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Hippocampal atrophy is a biomarker of initial cognitive decline in PD, including impaired memory encoding and storage, suggesting heterogeneity in the neural substrate of memory impairment.
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One in three adults over the age of 60 years will die with dementia.
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These preliminary study results show an association between human brain activity of microglia, astrocytes, and IL-6 and delirium in elderly patients and add to the accumulating evidence that inflammatory mechanisms are involved in delirium.
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Until relatively recently, most psychologists have had limited professional involvement with older adults.
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The quality of end-of-life care exists on a continuum across care settings.
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A stressful event increases the risk of developing depression later in life, but the possible predisposing factors remain unknown.
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The current evidence base for ACP in dementia is limited.
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The staff require education and support about discussing and implementing plans around care at the end of life in dementia and about cultural issues around death to improve practice.
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There is a critical need to potentially individualize new strategies able to prevent and to slow down the progression of predementia and dementia syndromes.
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It is widely accepted that inflammation plays some role in the progression of chronic neurodegenerative diseases such as AD (Alzheimer's disease), but its precise role remains elusive.
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Advance directives for euthanasia are never adhered to in the Netherlands in the case of people with advanced dementia, and their role in advance care planning and end-of-life care of people with advanced dementia is limited.
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The contribution of specific psychotropic drugs to fall risk in patients with dementia has not been quantified precisely until now.
From across this topic
10 of the 7,967 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Emergency Departments Leading the Transformation of Alzheimer's and Dementia Care
- Identifying the elderly at risk for malnutrition. The Mini Nutritional Assessment
- Mortality after the hospitalization of a spouse
- Collective physician perspectives on non-oral medication approaches for the management of clinically relevant unresolved issues in Parkinson's disease: Consensus from an international survey and discussion program
- MRI and CSF biomarkers in normal, MCI, and AD subjects: diagnostic discrimination and cognitive correlations
- Interplay of genetic predisposition, plasma metabolome and Mediterranean diet in dementia risk and cognitive function
- Care home leadership: action is needed
- Dementia praecox redux: a systematic review of the nicotinic receptor as a target for cognitive symptoms of schizophrenia
- Endogenous estradiol and risk of dementia in women and men: the Rotterdam Study
- Exploring the effect of multi-modal intervention against cognitive decline on atrophy and small vessel disease imaging markers in the AgeWell.de imaging study