Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
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Human immunodeficiency virus-type 1 (HIV-l) infection is the most common preventable and treatable cause of neurocognitive impairment in individuals under age 50 years.
Why it matters
This review describes cognitive impairment caused by HIV-1 infection, which is a different condition from Alzheimer's disease. It reports no treatment, cure, or prevention for Alzheimer's disease.
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As populations age, heart failure (HF) is becoming increasingly common, and in addition to a high burden of morbidity and mortality, HF has an enormous financial impact.
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In an inception cohort of 196 Olmsted County, Minnesota, residents with Parkinson's disease (PD) first recognized in 1976 to 1995, we tested whether the increased risk of bone fractures is associated with concomitant dementia.
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Different neuropsychological populations implicate diverse cortical regions in semantic memory: semantic dementia (SD) is characterized by atrophy of the anterior temporal lobes whilst poor comprehension in stroke aphasia is associated with prefrontal or temporal-parietal infarcts.
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Despite the use of highly active antiretroviral therapy (HAART), neuronal cell death remains a problem that is frequently found in the brains of HIV-1-infected patients.
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Measures to prevent the morbidity associated with falls and fractures in bradykinetic rigid syndromes may be best directed at patients with the risk factors identified in this study.
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From earliest times, psychiatrists have described biological rhythm disturbances as characteristic of mood disorders.
Why it matters
This review describes biological rhythm disturbances in mood disorders and notes that light therapy has promise for conditions including sleep-wake cycle disturbances in Alzheimer's dementia. It reports no evidence that light therapy treats, cures or prevents Alzheimer's disease itself.
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Brain areas implicated in the stress response include the amygdala, hippocampus, and prefrontal cortex.
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Patients with frontotemporal dementia (FTD) have sentence comprehension difficulty.
Why it matters
This study found that patients with frontotemporal dementia have sentence comprehension difficulty related to both grammatical and executive factors, in small subgroups of patients. It concerns understanding language problems in frontotemporal dementia, not treating, curing or preventing Alzheimer's disease.
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The present study explored several different procedures for determining the amount of change that occurred on the Mini-Mental State Exam [MMSE; Folstein, M. (1975).
Why it matters
This study looked at different ways to measure how much scores on the MMSE and 3MS change over short and long test-retest intervals. It is about interpreting these cognitive test scores over time, not about treating, curing or preventing Alzheimer's disease.
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To compare the diagnostic accuracies of the Revised Hasegawa Dementia Scale (HDS-R) and Mini-Mental Status Examination (MMSE) for Alzheimer's diseases (AD), we administered them simultaneously to 82 AD patients and 82 age- and sex-matched nondemented control subjects.
Why it matters
In 82 Alzheimer's disease patients and 82 matched controls, both the Revised Hasegawa Dementia Scale and the MMSE detected Alzheimer's disease well, but the Hasegawa scale was significantly more accurate. This concerns diagnosis only and does not address treating, curing or preventing the disease.
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These findings may facilitate the timely and efficient management of CDAD in nursing home patients.
Why it matters
This study identified risk factors for Clostridium difficile-associated disease in nursing home patients, including low albumin and proton pump inhibitor use. It does not address treating, curing or preventing Alzheimer's disease.
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Magnetic resonance imaging (MRI) has opened a new window to the brain.
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The advance of neuroimaging techniques has resulted in a burgeoning of studies reporting abnormalities in brain structure and function in a number of neuropsychiatric disorders.
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Essential components of the Mediterranean diet--MUFA, cereals and wine--seem to be protective against cognitive decline.
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We confirmed previous findings of smaller hippocampal volume in PTSD in a new population made up of police officers, excluding comorbidity as a confounder.
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A substantial proportion of stroke survivors have very poor HRQoL.
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Studies have found no evidence that feeding tubes in this population prevent aspiration, prolong life, improve overall function, or reduce pressure sores.
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Help-seeking was most often initiated by family members or formal care providers (ie, healthcare providers or social workers), usually in outpatient primary care settings but also elsewhere (eg, social service agencies, hospitals).
Why it matters
This qualitative interview study of 39 family dementia caregivers found four distinct pathways to diagnosis that varied across ethnic groups, along with cross-ethnic differences in adverse experiences. It describes help-seeking and diagnosis experiences and does not test a treatment, cure or prevention.
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Nine-hundred twenty-one community-dwelling patients 65 years of age or older, who sustained an operatively treated hip fracture from July 1, 1987 to June 30, 1998 were followed up for the development of postoperative delirium.
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40/100
Half of the patients with SSVD complained of varying severity of cognitive problems 3 months after stroke.
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Our findings provide new evidence of abnormalities in the hippocampus in early onset depression.
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40/100
Dementia with Lewy bodies (DLB) is the second commonest cause of neurodegenerative dementia in older people.
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Delirium in nondemented femoral neck fracture patients is associated with the development of dementia and a higher mortality rate.
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40/100
Measurement of local cerebral glucose metabolism (lCMRGlc) by positron emission tomography (PET) and 18F-2-fluoro-2-deoxy-D-glucose (FDG) has become a standard technique during the past 20 years and is now available at many university hospitals in all highly developed countries.
Why it matters
This report describes how PET scanning with FDG measures brain glucose metabolism and shows a pattern of regional impairment in Alzheimer's disease. It is a description of a diagnostic imaging technique, not a treatment, cure, or prevention study.
From across this topic
10 of the 7,967 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Associations of stressors and uplifts of caregiving with caregiver burden and depressive mood: a meta-analysis
- Long-term exposure to ambient air pollution and risk of dementia: Results of the prospective Three-City Study
- Medication Reconciliation and Education for Older Adults
- ACNP White Paper: update on use of antipsychotic drugs in elderly persons with dementia
- Cultural adaptation and psychometric validation of the Turkish MIND diet adherence scale for young adults
- Associations Between Ultra-Processed Food Consumption and Adverse Brain Health Outcomes
- Effect of Aspirin vs Placebo on the Prevention of Depression in Older People: A Randomized Clinical Trial
- Variation of the Risk Associated With Potentially Modifiable Risk Factors for Dementia Between Ethnic Groups Within One Country. A Retrospective Cohort Study Using Routinely Collected Health Data in Aotearoa New Zealand
- Caregiver Identity and Resilience Across and Beyond Dementia Care: A Qualitative Study
- Comprehensive Review of Lipid Management in Chronic Kidney Disease and Hemodialysis Patients: Conventional Approaches, and Challenges for Cardiovascular Risk Reduction