Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
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A study to estimate the prevalence of dementia in a rural population was conducted in a community located on the outskirts of Madras city in South India.
Why it matters
This study estimated the prevalence of dementia in a rural population in South India, finding 3.5% among people aged 60 and older. It is a description of how common dementia is in one setting, not a treatment, cure or prevention.
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Atrial fibrillation is common in patients residing in long-term care facilities, but its management with warfarin is highly variable.
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41/100
Degeneration of frontal and temporal lobes predisposes to antisocial behaviour.
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This study has shown that physical restraints are used frequently in geriatric care in Sweden and that cognitive and physical impairments relate very closely to the use of physical restraints.
Why it matters
This Swedish study found that 24% of geriatric care patients were physically restrained, and that cognitive and physical impairments related closely to restraint use. It is about care practices, not about treating, curing or preventing Alzheimer's disease.
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Interpretation of cognitive test performance among individuals from a given population requires an understanding of cognitive norms in that population.
Why it matters
This study reports cognitive test norms for nondemented elderly people in rural India who were largely illiterate. It does not test any treatment, cure, or prevention for Alzheimer's disease.
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Cerebral atrophy (CA) in stroke patients is associated with poststroke dementia and may reflect underlying neurodegenerative pathology.
Why it matters
This study tested a qualitative rating scale for cerebral atrophy on MRI in stroke patients, finding moderate to substantial interobserver agreement and good intraobserver agreement. It concludes that assessment of cerebral atrophy using this rating scale is possible in stroke patients, though the sample had a low prevalence of cerebral atrophy.
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Among the elderly, the prevalence of Alzheimer's disease and multi-infarct dementia, as opposed to depression, increases steeply with age.
Why it matters
This community study in Zaragoza, Spain, estimated the prevalence of dementia and depression in the elderly and found that case levels of depression were documented in about a quarter of dementia cases. It describes how these conditions occur together but does not test any treatment, cure, or prevention.
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Based on this study, type and degree of cognitive impairment are better predictors of driving skills than age or medical diagnosis per se.
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41/100
Evidence that dying occurs as a natural, final event in the wholeness of human life is culturally, artistically, and scientifically persuasive.
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The author reviewed the epidemiology and comorbidity of anxiety disorders in the elderly.
Why it matters
This review of community surveys found that anxiety disorders are generally less common in the elderly, and it examined how late-life anxiety relates to depression, dementia, alcoholism and medical illness. It concerns anxiety epidemiology and does not address treating, curing or preventing Alzheimer's disease.
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Nine Consortium to Establish a Registry for Alzheimer's Disease (CERAD) sites were surveyed to identify barriers to recruiting black subjects.
Why it matters
This survey of CERAD sites identified barriers to recruiting Black elderly people into dementia research, including expenses, transportation difficulties, and lack of rapport with clinic staff. It addresses recruitment only and does not test any treatment, cure, or prevention.
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The profile of aphasia suggests that primary progressive aphasia tends to affect anterior parts of the language-dominant cortex first.
Why it matters
In 10 patients with primary progressive aphasia, early stages typically showed reduced speech fluency and word-finding difficulty with preserved comprehension and nonverbal cognition, unlike patients with Alzheimer's disease or stroke-caused aphasia. This describes language profiles and does not treat, cure or prevent Alzheimer's disease.
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Hypertension-caused arteriosclerotic changes of the long penetrating medullary arteries may cause misery perfusion and later ischemic damage in the periventricular white matter.
Why it matters
This small study of eight hypertensive patients with leukoaraiosis found that those with dementia had markedly reduced white matter blood flow and oxygen metabolism, while those without dementia had less reduction and near-normal oxygen metabolism. It is a small clinical and imaging study and does not test any treatment, cure or prevention.
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We compared black (n = 33) and white (n = 119) caregivers of dementia patients on indices of adaptation, adjustment, and utilization of supportive services.
Why it matters
Black caregivers of dementia patients showed less burden and less desire to institutionalize their relatives than white caregivers and were more likely to report unmet service needs. This is about caregiver adaptation and service use, not about treating, curing, or preventing Alzheimer's disease.
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Dementing diseases cause a deterioration in the capacity for independent living skills (ILS).
Why it matters
This study found that Alzheimer's patients had significantly greater loss of insight into their independent living skill impairments compared to controls and multi-infarct dementia patients. It suggests that intervention strategies should consider the patient's level of insight and the caregiver's perception of the patient's capabilities.
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Probands (n = 3607) living in long-term care institutions in the county of Västerbotten were assessed to estimate whether the prevalence of dementia in different types of institutions had changed since a similar survey was made 7 years before.
Why it matters
This descriptive study of 3600 institutionalized patients in Sweden found about 40% were demented and that this proportion had increased since 1975. It describes patient characteristics and care burden, not treatment, cure or prevention of Alzheimer's disease.
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41/100
Five patients had progressive dementia heralded by disorders of higher visual function.
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Pharmacotherapy of aggressive or agitated behaviors in the dementia patient has not been studied extensively, despite the prevalence of this problem.
Why it matters
This review of pharmacologic treatment for agitation in dementia found that neuroleptics have the most support but are effective only for a minority of patients, and that side effects frequently make patients worse. It concerns managing agitation symptoms, not treating, curing, or preventing Alzheimer's disease itself.
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The development of FAST is of great importance to clinicians in identifying possibly remediable complications of Alzheimer's disease and distinguishing them from the characteristic progression of the illness.
Why it matters
This article discusses using a clinical approach to identify possibly reversible complications of Alzheimer's disease and to suspect focal cerebral pathology when speech is lost prematurely. It addresses clinical identification of reversible causes, not curing or preventing Alzheimer's disease itself.
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Artificial intelligence (AI) has stimulated extensive research in clinical neurology, but relatively few AI systems have meaningfully changed bedside decision-making.
Why it matters
This review proposes the NEURAL framework for artificial intelligence in neurology and notes that most clinically advanced AI examples come from acute stroke, while many high-performing dementia models have not been tested prospectively in real-world workflows. It concerns translating algorithms into practice and does not report any treatment, cure or prevention of Alzheimer's disease.
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The resulting framework is organized around 3 themes-vision, process, and impact-each containing guiding questions that encourage dialogical reflection and decision-making.
Why it matters
This tutorial presents an ethical framework organized around vision, process and impact to guide the development and use of locator devices in dementia care. It addresses ethical decision-making about technology and does not test any treatment, cure or prevention for Alzheimer's disease.
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Delirium is a common health problem with serious and long-lasting health consequences that disproportionately affects vulnerable population groups (especially older people with dementia or frailty).
Why it matters
This perspective argues that delirium is a common health problem with serious consequences that disproportionately affects vulnerable groups such as older people with dementia or frailty. It notes that multicomponent non-pharmacological interventions can prevent up to half of hospital-acquired delirium cases but are poorly prioritised, and calls for urgent policy reform in Australia.
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Both CDT formats showed clinically useful psychometric properties and similar pragmatic cut‐offs in older psychiatric outpatients.
Why it matters
In this study of 447 older psychiatric outpatients, two Clock Drawing Test formats correlated with MMSE and HDS-R totals and both identified the same screening cut-off. Education, functional disability, and both test formats predicted MMSE total.
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Of 4288 consultations with patients ≥65 years in the study periods, 402 (9.4%) involved possible or probable delirium.
Why it matters
This study found that about 10% of out-of-hours primary care consultations with patients aged 65 and over involved possible or probable delirium, and these patients were more often admitted to hospital. It describes how delirium presents in urgent care and does not test any treatment, cure or prevention for Alzheimer's disease.
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Understanding regional and racial variation in the risk of hospitalization with Alzheimer's disease and related dementias (ADRD)-and how it differs from other conditions-is required to inform effective practice and policy.
Why it matters
Among Black and White Medicare beneficiaries, hospitalization risk with Alzheimer's disease and related dementias varied by region and race. Black relative risk was significantly higher than White relative risk in 90.2% of counties for hospitalization with dementia.
From across this topic
10 of the 7,967 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Frail patients are at increased risk for mortality and prolonged institutional care after cardiac surgery
- Stroke, disability, and dementia: results of a population survey
- Prevalence of neuropsychiatric symptoms in mild cognitive impairment and normal cognitive aging: population-based study
- Homocysteine and cognitive decline in healthy elderly
- Updating the Evidence for Physical Activity: Summative Reviews of the Epidemiological Evidence, Prevalence, and Interventions to Promote "Active Aging"
- Hearing loss and cognition: the role of hearing AIDS, social isolation and depression
- Spatial Reorganization and Governance Synergy: Innovative Practices for Strengthening County-Level Wealth-Creating Industries—A Case Study of the Huameidani Area
- Incidence of dementia after ischemic stroke: results of a longitudinal study
- Companion robots for older people: importance of user-centred design demonstrated through observations and focus groups comparing preferences of older people and roboticists in South West England
- Sex differences in the association between AD biomarkers and cognitive decline