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Associations Between Ultra-Processed Food Consumption and Adverse Brain Health Outcomes
Bhave VM, Oladele CR, Ament Z, Kijpaisalratana N, Jones AC, Couch CA, Patki A, Garcia Guarniz AL et al.. Neurology, 2024-05-22
Topic: Risk, prevention and care in population studies
Results The cognitive impairment cohort (n = 14,175) included participants without evidence of impairment at baseline who underwent follow-up testing. In multivariable Cox proportional hazards models, a 10% increase in relative intake of UPFs was associated with higher risk of cognitive impairment (hazard ratio [HR] = 1.16, 95% CI 1.09-1.24, p = 1.01 × 10 -5 ) and intake of unprocessed or minimally processed foods with lower risk of cognitive impairment (HR = 0.88, 95% CI 0.83-0.94, p = 1.83 × 10 -4 ). Greater intake of UPFs (HR = 1.08, 95% CI 1.02-1.14, p = 1.12 × 10 -2 ) and unprocessed or minimally processed foods (HR = 0.91, 95% CI 0.86-0.95, p = 2.13 × 10 -4 ) were also associated with risk of stroke in multivariable Cox models.
Key findings
- Results The cognitive impairment cohort (n = 14,175) included participants without evidence of impairment at baseline who underwent follow-up testing.
- In multivariable Cox proportional hazards models, a 10% increase in relative intake of UPFs was associated with higher risk of cognitive impairment (hazard ratio [HR] = 1.16, 95% CI 1.09-1.24, p = 1.01 × 10 -5 ) and intake of unprocessed or minimally processed foods with lower risk of cognitive impairment (HR = 0.88, 95% CI 0.83-0.94, p = 1.83 × 10 -4 ).
- Greater intake of UPFs (HR = 1.08, 95% CI 1.02-1.14, p = 1.12 × 10 -2 ) and unprocessed or minimally processed foods (HR = 0.91, 95% CI 0.86-0.95, p = 2.13 × 10 -4 ) were also associated with risk of stroke in multivariable Cox models.
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Study details
- Study designcohort study
- Participants14,175
- Effect sizeHR = 0.88; HR = 1.08; HR = 0.91
- Evidence strengthModerate
How this study scored 78/100
Published in a leading specialty journal, and it is a cohort study following people over time. Scored zero for randomised / blinded because the record does not state it. We have no data on journal's citation record, times cited, citations per year, impact for its field and year, cited by studies here, still being cited, senior author's track record, institution's track record and multi-centre collaboration, so those were left out: it earned 45 of the 58 points we could judge it on, which is 78 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 9 / 10 | Tier 2 — leading specialty journal (Neurology) |
| Journal's citation record | — / 4 | No journal record from OpenAlex — left out of this score |
| Study design | 7 / 12 | A cohort study following people over time |
| Strength of evidence | 3 / 5 | Rated “moderate” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2024 — within 3 year(s) of the newest study here |
| Sample size | 4 / 4 | 14,175 participants |
| Effect reported | 3 / 3 | Effect reported with a statistic (interval, p-value, ratio or similar) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | — / 7 | No citation count (not found in OpenAlex) — left out of this score |
| Citations per year | — / 5 | No citation count or no year — left out of this score |
| Impact for its field and year | — / 6 | No field-weighted citation impact (OpenAlex has none yet) — left out of this score |
| Cited by studies here | — / 6 | Not yet checked against this library's citation graph — left out of this score |
| Still being cited | — / 4 | No yearly citation counts — left out of this score |
| Senior author's track record | — / 4 | Senior author's record not available — left out of this score |
| Institution's track record | — / 3 | No institution listed in OpenAlex — left out of this score |
| Multi-centre collaboration | — / 3 | Institutions not listed — left out of this score |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 38776524) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Points | 45 / 58 | Scored on 11 of 20 parts. We have no data for the rest, so they are left out: 45 of the 58 points we could judge it on is 78 out of 100. |
| Total | 78 / 100 | — |
What each of these 20 components measures, and what this score is not →
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Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.
APA 7th
Bhave, V. M., Oladele, C. R., Ament, Z., Kijpaisalratana, N., Jones, A. C., Couch, C. A., et al. (2024). Associations Between Ultra-Processed Food Consumption and Adverse Brain Health Outcomes. Neurology. https://doi.org/10.1212/wnl.0000000000209432
Vancouver
Bhave VM, Oladele CR, Ament Z, Kijpaisalratana N, Jones AC, Couch CA, et al. Associations Between Ultra-Processed Food Consumption and Adverse Brain Health Outcomes. Neurology. 2024. doi:10.1212/wnl.0000000000209432. PMID: 38776524.
BibTeX
@article{bhave2024-38776524,
author = {Bhave, V. M. and Oladele, C. R. and Ament, Z. and Kijpaisalratana, N. and Jones, A. C. and Couch, C. A. and Patki, A. and Garcia Guarniz, A. L. and others},
title = {{Associations Between Ultra-Processed Food Consumption and Adverse Brain Health Outcomes}},
journal = {Neurology},
year = {2024},
doi = {10.1212/wnl.0000000000209432},
pmid = {38776524},
url = {https://doi.org/10.1212/wnl.0000000000209432}
}
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