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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 24,301–24,325 of 27,380 studies, newest first · page 973 of 1096.

December 2003 15

  1. 2003-12-01

    Use of Restraints on Dementia Patients

    ✓ Peer-reviewed Health systems and care delivery JONA s Healthcare Law Ethics and Regulation

    Key finding: The project exposes a discrepancy between the manner in which the nursing staff perceive use of restraints in an idealistic situation and in a realistic situation and the greater tendency to use restraints in the realistic situation than in the idealistic situation. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2003-12-01

    Use of restraints on dementia patients: an ethical dilemma of a nursing staff in Israel

    ✓ Peer-reviewed Health systems and care delivery JONA'S healthcare law, ethics and regulation

    Key finding: The project exposes a discrepancy between the manner in which the nursing staff perceive use of restraints in an idealistic situation and in a realistic situation and the greater tendency to use restraints in the realistic situation than in the idealistic situation. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2003-12-01

    Vascular pathology in Alzheimer disease: correlation of cerebral amyloid angiopathy and arteriosclerosis/lipohyalinosis with cognitive decline

    ✓ Peer-reviewed Brain tissue and pathology Journal of neuropathology and experimental neurology

    Key finding: AD-related pathology is often accompanied by vascular changes. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2003-12-01

    Comparison of the short test of mental status and the mini-mental state examination in mild cognitive impairment

    ✓ Peer-reviewed Cognitive tests and assessment Archives of neurology

    Key finding: The Mini-Mental State Examination (MMSE) is the most widely used brief screening measure of cognition, but it is not sensitive in detecting mild memory or other cognitive impairments. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2003-12-01

    Environmental enrichment exacerbates amyloid plaque formation in a transgenic mouse model of Alzheimer disease

    ✓ Peer-reviewed Risk genes beyond APOE Journal of neuropathology and experimental neurology

    Key finding: A model of environmental manipulation in rodents uses enriched housing to provide cognitive and social stimulation. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2003-12-01

    Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses

    ✓ Peer-reviewed Risk genes beyond APOE Neurobiology of aging

    Key finding: This is accompanied by an aberrant behavior of the microtubule-associated protein tau (hyperphosphorylation, aggregation). +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2003-12-01

    Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death

    ✓ Peer-reviewed Risk genes beyond APOE Neuron

    Key finding: Upregulation of proteases that degrade Abeta thus represents a novel therapeutic approach to lowering steady-state Abeta levels, but the consequences of sustained upregulation in vivo have not been studied. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2003-12-01

    Distinctive neuropsychological patterns in frontotemporal dementia, semantic dementia, and Alzheimer disease

    ✓ Peer-reviewed Lewy body dementia Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology

    Key finding: Frontotemporal dementia, semantic dementia, and Alzheimer disease are associated with distinct neuropsychological profiles that classify these dementia syndromes with considerable success. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2003-12-01

    Stroke and the risk of Alzheimer disease

    ✓ Peer-reviewed Risk factors Archives of neurology

    Key finding: Stroke is associated with AD among elderly individuals. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2003-12-01

    Barriers to limiting the practice of feeding tube placement in advanced dementia

    ✓ Peer-reviewed Digital health tools Journal of palliative medicine

    Key finding: We find a notable discord between physician opinion, reported practice, and the literature regarding PEG tubes in advanced dementia that reveals some of the barriers to decreasing the referral of these patients for PEG. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2003-12-01

    The savvy caregiver program: developing and testing a transportable dementia family caregiver training program

    ✓ Peer-reviewed Disparities The Gerontologist

    Key finding: Virtually all respondents reported increased skill, knowledge, and confidence, and all would recommend the program to others. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2003-12-01

    Nursing home staff attitudes towards residents with dementia: strain and satisfaction with work

    ✓ Peer-reviewed Caregiving Journal of advanced nursing

    Key finding: Nursing home staff tended to perceive residents in more negative than positive ways. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2003-12-01

    Patient and caregiver characteristics associated with depression in caregivers of patients with dementia

    ✓ Peer-reviewed Caregiving Journal of general internal medicine

    Key finding: The goal of this study was to determine the patient and caregiver characteristics associated with depression among caregivers of patients with dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2003-12-01

    Cerebrospinal fluid tau and beta-amyloid: how well do these biomarkers reflect autopsy-confirmed dementia diagnoses?

    ✓ Peer-reviewed Getting a diagnosis Archives of neurology

    Key finding: Elevated CSF tau levels are associated with AD pathology and can help discriminate AD from other dementing disorders. +2 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2003-12-01

    Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial

    ✓ Peer-reviewed Treatments Archives of neurology

    Key finding: Subject to the usual caveats inherent in studies with small sample size, this pilot phase 2 study supports further investigation of this novel treatment strategy using a metal-protein-attenuating compound. +1 more finding

    Full summary, score breakdown and related studies → Original source

November 2003 10

  1. 2003-11-25

    Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase

    ✓ Peer-reviewed Biomarkers Human molecular genetics

    Key finding: Missense mutations in PS1 (and PS2) occur in patients with early-onset familial AD (FAD), and previous studies in transgenic mice and cultured cell models demonstrated that FAD-PS1 variants shift the ratio of Abeta40 : 42 to favor Abeta42. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2003-11-19

    Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotective

    ✓ Peer-reviewed How common it is The Journal of biological chemistry

    Key finding: Although the caspase inhibitor z-VAD-fmk significantly reduced the number of apoptotic cells, it had no impact on the percentage of aggresome-positive cells. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2003-11-07

    Deaths: leading causes for 2001

    ✓ Peer-reviewed Disparities PubMed

    Key finding: In 2001, the 10 leading causes of death were (in rank order) Diseases of heart; Malignant neoplasms; Cerebrovascular diseases; Chronic lower respiratory diseases; Accidents (unintentional injuries); Diabetes mellitus; Influenza and pneumonia; Alzheimer's disease; Nephritis, nephrotic syndrome and nephrosis; and Septicemia and accounted for nearly 80 percent of all deaths occurring in the United States. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2003-11-07

    Functional deactivations: change with age and dementia of the Alzheimer type

    ✓ Peer-reviewed Brain scans and imaging Proceedings of the National Academy of Sciences of the United States of America

    Key finding: The temporal profile of the medial parietal/posterior cingulate response suggested that it was initially activated by all three groups, but the response in young adults quickly reversed sign, whereas DAT individuals maintained activation throughout the task block. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2003-11-02

    Validity of a novel computerized cognitive battery for mild cognitive impairment

    ✓ Peer-reviewed Cognitive tests and assessment BMC geriatrics

    Key finding: Mindstreams tests are effective in detecting MCI, providing a comprehensive profile of cognitive function.

    Full summary, score breakdown and related studies → Original source

  6. 2003-11-01

    Structural Insights and Biological Effects of Glycogen Synthase Kinase 3-specific Inhibitor AR-A014418

    ✓ Peer-reviewed Risk factors Journal of Biological Chemistry

    Key finding: AR-A014418 does not significantly inhibit cdk2 or cdk5 (IC50 > 100 microM) or 26 other kinases demonstrating high specificity for GSK3. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2003-11-01

    Plasma antioxidants are similarly depleted in mild cognitive impairment and in Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment Neurobiology of aging

    Key finding: Peripheral levels and activities of antioxidants were similarly lower in MCI and AD patients as compared to controls.

    Full summary, score breakdown and related studies → Original source

  8. 2003-11-01

    Influence of executive function on locomotor function: divided attention increases gait variability in Alzheimer's disease

    ✓ Peer-reviewed Digital health tools Journal of the American Geriatrics Society

    Key finding: Divided attention markedly impairs the ability of patients with AD to regulate the stride-to-stride variations in gait timing. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2003-11-01

    A multicenter, placebo-controlled trial of melatonin for sleep disturbance in Alzheimer's disease

    ✓ Peer-reviewed Risk factors Sleep

    Key finding: Based on actigraphy as an objective measure of sleep time, melatonin is not an effective soporific agent in people with Alzheimer's disease. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2003-11-01

    Randomized, placebo-controlled trial of the effects of donepezil on neuronal markers and hippocampal volumes in Alzheimer's disease

    ✓ Peer-reviewed Hippocampus size on brain scans The American journal of psychiatry

    Key finding: These preliminary results suggest that donepezil may have a potentially protective effect in Alzheimer's disease. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →