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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 25,801–25,825 of 27,380 studies, newest first · page 1033 of 1096.

March 1999 5

  1. 1999-03-01

    Translation of the alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5'-untranslated region sequences

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: Inflammation is also associated with AD as exemplified by increased expression of interleukin-1 (IL-1) in microglia in affected areas of the AD brain. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 1999-03-01

    Structural maturation of neural pathways in children and adolescents: in vivo study

    ✓ Peer-reviewed Lewy body dementia Science (New York, N.Y.)

    Key finding: A computational analysis of structural magnetic resonance images obtained in 111 children and adolescents revealed age-related increases in white matter density in fiber tracts constituting putative corticospinal and frontotemporal pathways. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 1999-03-01

    Mild cognitive impairment: clinical characterization and outcome

    ✓ Peer-reviewed How common it is Archives of neurology

    Key finding: Patients who meet the criteria for MCI can be differentiated from healthy control subjects and those with very mild AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 1999-03-01

    Development of an activities of daily living scale to screen for dementia in an illiterate rural older population in India

    ✓ Peer-reviewed Disparities Age and ageing

    Key finding: Design identification of relevant items, pre-testing of items and refinement of administrative procedures and scoring in four successive groups of 30 subjects each, pilot testing in a group of 100 subjects comparable to those for whom the measure is intended, administration to a representative sample of 387 people aged 55 and older, and assessment of the reliability of the final measure. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 1999-03-01

    The temporal relationship between depressive symptoms and dementia: a community-based prospective study

    ✓ Peer-reviewed Disparities Archives of general psychiatry

    Key finding: Depressive symptoms appeared to be early manifestations, rather than predictors, of Alzheimer disease in this community sample. +2 more findings

    Full summary, score breakdown and related studies → Original source

February 1999 15

  1. 1999-02-01

    Evaluation of the NINCDS-ADRDA criteria in the differentiation of Alzheimer's disease and frontotemporal dementia

    ✓ Peer-reviewed Lewy body dementia Journal of Neurology Neurosurgery & Psychiatry

    Key finding: (1) The overall sensitivity of the NINCDS-ADRDA criteria in diagnosing "probable" AD from 56 patients with cortical dementia (AD and FTD) was 0.93. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 1999-02-01

    Misclassification and selection bias when identifying Alzheimer's disease solely from Medicare claims records

    ✓ Peer-reviewed Digital health tools Journal of the American Geriatrics Society

    Key finding: Underclassification of dementia from claims records can be partially remedied by increasing the period during which claims are compiled, but additional diagnostic sources will likely be needed to increase prevalence counts closer to 100% of true cases. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 1999-02-01

    Chronic stress in elderly carers of dementia patients and antibody response to influenza vaccination

    ✓ Peer-reviewed Caregiving Lancet (London, England)

    Key finding: Mean scores of emotional distress were significantly higher in carers at each time point than in controls (all p<0.0003). +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 1999-02-01

    Memantine in severe dementia: results of the 9M-Best Study (Benefit and efficacy in severely demented patients during treatment with memantine)

    ✓ Peer-reviewed Treatments International journal of geriatric psychiatry

    Key finding: The results of this trial support the hypothesis that memantine treatment leads to functional improvement and reduces care dependence in severely demented patients. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 1999-02-01

    The cholinergic hypothesis of Alzheimer's disease: a review of progress

    ✓ Peer-reviewed Treatments Journal of neurology, neurosurgery, and psychiatry

    Key finding: Alzheimer's disease is one of the most common causes of mental deterioration in elderly people, accounting for around 50%-60% of the overall cases of dementia among persons over 65 years of age.

    Full summary, score breakdown and related studies → Original source

  6. 1999-02-01

    Increased poly(ADP-ribosyl)ation of nuclear proteins in Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Brain : a journal of neurology

    Key finding: Experimental studies indicate that overactivation of the DNA repair protein poly(ADP-ribose) polymerase (PARP) in response to oxidative damage to DNA can cause cell death due to depletion of NAD+. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 1999-02-01

    Hippocampal volume in first-episode psychoses and chronic schizophrenia: a high-resolution magnetic resonance imaging study

    ✓ Peer-reviewed Hippocampus size on brain scans Archives of general psychiatry

    Key finding: These data show that smaller hippocampal volumes are present from the onset of illness. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 1999-02-01

    A distinct familial presenile dementia with a novel missense mutation in the tau gene

    ✓ Peer-reviewed Disease mechanisms Neuroreport

    Key finding: Imaging studies showed fronto-temporal atrophy with ventricular dilatation more on the left, and postmortem examination of the brain revealed numerous neurofibrillary tangles (NFTs) with an unusual morphology and distribution.

    Full summary, score breakdown and related studies → Original source

  9. 1999-02-01

    Cortical surface-based analysis. I. Segmentation and surface reconstruction

    ✓ Peer-reviewed Brain scans and imaging NeuroImage

    Key finding: Here we describe a set of automated procedures for obtaining accurate reconstructions of the cortical surface, which have been applied to data from more than 100 subjects, requiring little or no manual intervention. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 1999-02-01

    Chemokines/chemokine receptors in the central nervous system and Alzheimer's disease

    ✓ Peer-reviewed Inflammation and the immune system Journal of neurovirology

    Key finding: Its pathological changes include amyloid beta deposits, neurofibrillary tangles and a variety of 'inflammatory' phenomenon such as activation of microglia and astrocytes. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 1999-02-01

    Education and the incidence of dementia in a large population-based study: the Rotterdam Study

    ✓ Peer-reviewed Long-term cohort studies Neurology

    Key finding: In the Rotterdam Study, 6,827 nondemented participants with known education level were followed for an average of 2.1 years. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 1999-02-01

    Comparison of risperidone and placebo for psychosis and behavioral disturbances associated with dementia: a randomized, double-blind trial. Risperidone Study Group

    ✓ Peer-reviewed Lewy body dementia The Journal of clinical psychiatry

    Key finding: The study was completed by 70% of the patients. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 1999-02-01

    Type 2 diabetes mellitus, cognitive impairment and dementia

    ✓ Peer-reviewed Risk factors Diabetic medicine : a journal of the British Diabetic Association

    Key finding: Current classification structures for dementia may not be adequate in diabetes, where mixed pathogenesis is likely.

    Full summary, score breakdown and related studies → Original source

  14. 1999-02-01

    Contrasting results between caregiver's report and direct assessment of activities of daily living in patients affected by mild and very mild dementia: the contribution of the caregiver's personal characteristics

    ✓ Peer-reviewed Caregiving Journal of the American Geriatrics Society

    Key finding: With the exception of motor performance (walking), the caregiver's report and the performance-based assessment of functional status measure different aspects of a patient's functional status.

    Full summary, score breakdown and related studies → Original source

  15. 1999-02-01

    Age of onset in Huntington disease: sex specific influence of apolipoprotein E genotype and normal CAG repeat length

    ✓ Peer-reviewed Genetics Journal of medical genetics

    Key finding: In addition to highlighting the effect of the normal repeat length upon AO in maternally inherited HD and in male patients, we show that the APOE epsilon2epsilon3 genotype is associated with significantly earlier AO in males than in females. +1 more finding

    Full summary, score breakdown and related studies → Original source

January 1999 5

  1. 1999-01-01

    Decreased Melatonin Levels in Postmortem Cerebrospinal Fluid in Relation to Aging, Alzheimer’s Disease, and Apolipoprotein E-ε4/4 Genotype1

    ✓ Peer-reviewed Risk factors The Journal of Clinical Endocrinology & Metabolism

    Key finding: The melatonin level in AD patients expressing apolipoprotein E-epsilon3/4 (71 +/- 11 pg/mL) was significantly higher than that in patients expressing apolipoprotein E-epsilon4/4 (32 +/- 8 pg/ml; P = 0.02). +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 1999-01-01

    Microglia as mediators of inflammatory and degenerative diseases

    ✓ Peer-reviewed Inflammation and the immune system Annual review of neuroscience

    Key finding: Microglia are the principal immune cells in the central nervous system (CNS) and have a critical role in host defense against invading microorganisms and neoplastic cells. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1999-01-01

    Cyclooxygenase-2: molecular biology, pharmacology, and neurobiology

    ✓ Peer-reviewed Risk factors Critical reviews in neurobiology

    Key finding: New molecular and pharmacologic tools have provided a better understanding of the roles of COX-generated prostanoids in the nervous system. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 1999-01-01

    Alpha-1 noradrenergic receptor stimulation impairs prefrontal cortical cognitive function

    ✓ Peer-reviewed Drug development Biological psychiatry

    Key finding: These findings demonstrate that alpha-1 adrenoceptor stimulation in the PFC impairs cognitive function. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 1999-01-01

    Clinical correlates of vascular parkinsonism

    ✓ Peer-reviewed Vascular contributions Archives of neurology

    Key finding: These differences in clinical features suggest a different pathogenesis of parkinsonism in these 2 patient groups. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →