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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 25,376–25,400 of 27,380 studies, newest first · page 1016 of 1096.

September 2000 15

  1. 2000-09-01

    Prospective and retrospective memory in normal ageing and dementia: a questionnaire study

    ✓ Peer-reviewed Caregiving Memory (Hove, England)

    Key finding: Data from the couples indicated that there were no biases resulting from rating on behalf of someone else. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2000-09-01

    Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity

    ✓ Peer-reviewed Disease mechanisms The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: We now report that homocysteine induces apoptosis in rat hippocampal neurons. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2000-09-01

    Folic acid: nutritional biochemistry, molecular biology, and role in disease processes

    ✓ Peer-reviewed Prevention and risk Molecular genetics and metabolism

    Key finding: Folic acid prevents neural tube defects like spina bifida, while its ability to lower homocysteine suggests it might have a positive influence on cardiovascular disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2000-09-01

    Oxidative stress and apoptosis

    ✓ Peer-reviewed Risk factors Pathophysiology : the official journal of the International Society for Pathophysiology

    Key finding: Recent studies have demonstrated that reactive oxygen species (ROS) and the resulting oxidative stress play a pivotal role in apoptosis. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2000-09-01

    Neuron-specific phosphorylation of Alzheimer's beta-amyloid precursor protein by cyclin-dependent kinase 5

    ✓ Peer-reviewed Drug development Journal of neurochemistry

    Key finding: Treatment of mature neurons with an antisense oligonucleotide to Cdk5 suppressed Cdk5 expression and significantly diminished the level of phosphorylated APP. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2000-09-01

    X-34, a fluorescent derivative of Congo red: a novel histochemical stain for Alzheimer's disease pathology

    ✓ Peer-reviewed Drug development The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society

    Key finding: Comparison to standard methods of demonstrating AD pathology showed that X-34 correlated well with Bielschowsky and thioflavin-S staining. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2000-09-01

    Three-dimensional mapping of cortical thickness using Laplace's equation

    ✓ Peer-reviewed Brain scans and imaging Human brain mapping

    Key finding: We present graphical results that map cortical thickness everywhere in a normal brain. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2000-09-01

    Palliative care consultations: how do they impact the care of hospitalized patients?

    ✓ Peer-reviewed End-of-life care Journal of pain and symptom management

    Key finding: PCS consultations result in multiple recommendations with a very high implementation rate.

    Full summary, score breakdown and related studies → Original source

  9. 2000-09-01

    The application of the principles of geriatrics to the management of the older person with cancer

    ✓ Peer-reviewed Clinical safety Critical reviews in oncology/hematology

    Key finding: The risk of comorbid conditions increases with age and may result in underdiagnosis: in older patients, new symptoms may not be clearly recognized by the patient and may be dismissed by practitioners as manifestations of preexisting conditions. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2000-09-01

    Repetitive speech phenomena in Parkinson's disease

    ✓ Peer-reviewed Digital health tools Journal of neurology, neurosurgery, and psychiatry

    Key finding: Patients with advanced Parkinson's disease had a significantly higher disease impairment, longer disease duration, and an unstable motor response to levodopa with frequent on-off fluctuations. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2000-09-01

    Epidemiology of dementia in Nigeria: results from the Indianapolis-Ibadan study

    ✓ Peer-reviewed Disparities European journal of neurology

    Key finding: The findings were compared with those of 2212 African Americans living in Indianapolis, studied simultaneously using similar methodology. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2000-09-01

    The Clinician Assessment of Fluctuation and the One Day Fluctuation Assessment Scale. Two methods to assess fluctuating confusion in dementia

    ✓ Peer-reviewed Getting a diagnosis The British journal of psychiatry : the journal of mental science

    Key finding: Both scales are useful instruments for the clinical assessment of fluctuation in dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2000-09-01

    Double-blind, randomized, placebo-controlled pilot study with anapsos in senile dementia: effects on cognition, brain bioelectrical activity and cerebral hemodynamics

    ✓ Peer-reviewed Treatments Methods and findings in experimental and clinical pharmacology

    Key finding: Patients receiving 360 mg/day of anapsos showed a significant improvement in cognitive performance after treatment (ADAScog scores: p < 0.05) that was not observed in patients treated with placebo or 720 mg/day of anapsos. +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2000-09-01

    Apolipoprotein E and Alzheimer disease: an update on genetic and functional analyses

    ✓ Peer-reviewed Genetics Journal of neuropathology and experimental neurology

    Key finding: In vitro and animal model studies strongly suggest that brain apolipoprotein E is a multifunctional molecule, with potential roles in amyloid deposition and clearance, microtubule stability, intracellular signaling, immune modulation, glucose metabolism, oxidative stress, and other cellular processes.

    Full summary, score breakdown and related studies → Original source

  15. 2000-09-01

    Effects of age on gene expression during estrogen-induced synaptic sprouting in the female rat

    ✓ Peer-reviewed Biomarkers Experimental neurology

    Key finding: The data suggest that the estrogen-induced decrease of GFAP in response to lesions does not persist at 7 days post-ECL during sprouting. +1 more finding

    Full summary, score breakdown and related studies → Original source

August 2000 10

  1. 2000-08-22

    Rates of hippocampal atrophy correlate with change in clinical status in aging and AD

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Rates of hippocampal atrophy match both baseline cognitive status and the change in cognitive status over time in elderly persons who lie along the cognitive continuum from normal to MCI to AD.

    Full summary, score breakdown and related studies → Original source

  2. 2000-08-15

    Apolipoprotein E isoforms in Alzheimer's disease pathology and etiology

    ✓ Peer-reviewed Genetics Microscopy research and technique

    Key finding: AD patients with epsilon4 show more neuritic deficits than epsilon3 carriers. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2000-08-01

    alpha-synuclein promotes mitochondrial deficit and oxidative stress

    ✓ Peer-reviewed Disease mechanisms The American journal of pathology

    Key finding: Because neurodegeneration in these conditions might be associated with mitochondrial dysfunction and oxidative stress, the effects of alpha-synuclein were investigated in a hypothalamic neuronal cell line (GT1-7). alpha-Synuclein overexpression in these cells resulted in formation of alpha-synuclein-immunopositive inclusion-like structures and mitochondrial alterations accompanied by increased levels of free radicals and decreased secretion of gonadotropin-releasing hormone. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2000-08-01

    Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention

    ✓ Peer-reviewed Disease mechanisms Toxicology

    Key finding: A large number of synthetic and natural antioxidants have been demonstrated to induce beneficial effects on human health and disease prevention. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2000-08-01

    Glutathione, oxidative stress and neurodegeneration

    ✓ Peer-reviewed Vascular contributions European journal of biochemistry

    Key finding: There is significant evidence that the pathogenesis of several neurodegenerative diseases, including Parkinson's disease, Alzheimer's disease, Friedreich's ataxia and amyotrophic lateral sclerosis, may involve the generation of reactive oxygen species and mitochondrial dysfunction. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2000-08-01

    Predictors of nursing home placement in Parkinson's disease: a population-based, prospective study

    ✓ Peer-reviewed Risk factors Journal of the American Geriatrics Society

    Key finding: Both motor and neuropsychiatric symptoms contributed to institutionalization, but the presence of hallucinations was the strongest predictor. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2000-08-01

    Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model

    ✓ Peer-reviewed Risk genes beyond APOE Neurobiology of disease

    Key finding: Recent data suggest that cholesterol metabolism is linked to susceptibility to Alzheimer's disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2000-08-01

    Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease

    ✓ Peer-reviewed Biomarkers The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Several epidemiological studies have demonstrated a reduced risk for AD in patients using nonsteroidal anti-inflammatory drugs (NSAIDs), prompting further inquiries about how NSAIDs might influence the development of AD pathology and inflammation in the CNS. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2000-08-01

    Relation between age-related decline in intelligence and cerebral white-matter hyperintensities in healthy octogenarians: a longitudinal study

    ✓ Peer-reviewed Vascular contributions Lancet (London, England)

    Key finding: Scores for periventricular hyperintensities in this sample included all possible degrees of severity, but no participant scored more than 75% of maximum for deep white-matter hyperintensities. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2000-08-01

    Melatonin for treatment of sundowning in elderly persons with dementia - a preliminary study

    ✓ Peer-reviewed Clinical safety Archives of gerontology and geriatrics

    Key finding: Age-related sleep disorders are frequently associated with disruption of circadian cycle rhythms, and sometimes with 'sundowning'. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →