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Pharmaceutical Treatment for Alzheimer's Disease and Related Dementias: Utilization and Disparities
Douglas Barthold, Geoffrey Joyce, Patricia Ferido, Emmanuel F Drabo, Zachary A Marcum, Shelly L Gray, Julie Zissimopoulos. Journal of Alzheimer's disease : JAD, 2020
Topic: Drug trials: efficacy and safety
Among persons diagnosed with ADRD or related symptoms, 33.3% used an approved drug over the study period. Odds of use was higher among Whites than non-Whites. Among ADRD drug users, 40% initiated use within 6 months of the initial ADRD or related symptoms diagnosis, and 16% initiated prior to a diagnosis. We observed disparities by race/ethnicity: 28% of Asians, 24% of Hispanics, 16% of Blacks, and 15% of Whites initiated prior to diagnosis. The use of antidementia drugs is relatively low and varies widely by race/ethnicity. Heterogeneity in timing of initiation and use may affect health and cost outcomes, but these effects merit further study.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Barthold, D., Joyce, G., Ferido, P., Drabo, E. F., Marcum, Z. A., Gray, S. L., et al. (2020). Pharmaceutical Treatment for Alzheimer's Disease and Related Dementias: Utilization and Disparities. Journal of Alzheimer's disease : JAD. https://doi.org/10.3233/jad-200133
Vancouver
Barthold D, Joyce G, Ferido P, Drabo EF, Marcum ZA, Gray SL, et al. Pharmaceutical Treatment for Alzheimer's Disease and Related Dementias: Utilization and Disparities. Journal of Alzheimer's disease : JAD. 2020. doi:10.3233/jad-200133. PMID: 32538845.
BibTeX
@article{barthold2020-32538845,
author = {Barthold, Douglas and Joyce, Geoffrey and Ferido, Patricia and Drabo, Emmanuel F and Marcum, Zachary A and Gray, Shelly L and Zissimopoulos, Julie},
title = {{Pharmaceutical Treatment for Alzheimer's Disease and Related Dementias: Utilization and Disparities}},
journal = {Journal of Alzheimer's disease : JAD},
year = {2020},
doi = {10.3233/jad-200133},
pmid = {32538845},
url = {https://doi.org/10.3233/jad-200133}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record names 7 authors; APA and Vancouver show the first six, BibTeX and the downloads carry all of them. Check the citation against the original before you use it.
Key findings
- Among persons diagnosed with ADRD or related symptoms, 33.3% used an approved drug over the study period.
- Odds of use was higher among Whites than non-Whites.
- Among ADRD drug users, 40% initiated use within 6 months of the initial ADRD or related symptoms diagnosis, and 16% initiated prior to a diagnosis.
- We observed disparities by race/ethnicity: 28% of Asians, 24% of Hispanics, 16% of Blacks, and 15% of Whites initiated prior to diagnosis.
- The use of antidementia drugs is relatively low and varies widely by race/ethnicity.
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Study details
- Effect size33.3%
- Evidence strengthLow
How this study scored 43/100
Published in a peer-reviewed journal. Scored zero for study design, sample size, studied in people and randomized / blinded because the record does not state it. We have no data on journal's citation record, times cited, citations per year, impact for its field and year, cited by studies here, still being cited, senior author's track record, institution's track record, multicenter collaboration and free to read, so those were left out: it earned 24 of the 56 points we could judge it on, which is 43 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Journal of Alzheimer's disease : JAD) |
| Journal's citation record | — / 4 | No journal record from OpenAlex — left out of this score |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 2 / 5 | 2020 — within 10 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 2 / 3 | Effect reported as a number, without an interval or test |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomized / blinded | 0 / 2 | No randomization or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | — / 7 | No citation count (not found in OpenAlex) — left out of this score |
| Citations per year | — / 5 | No citation count or no year — left out of this score |
| Impact for its field and year | — / 6 | No field-weighted citation impact (OpenAlex has none yet) — left out of this score |
| Cited by studies here | — / 6 | Not yet checked against this library's citation graph — left out of this score |
| Still being cited | — / 4 | No yearly citation counts — left out of this score |
| Senior author's track record | — / 4 | Senior author's record not available — left out of this score |
| Institution's track record | — / 3 | No institution listed in OpenAlex — left out of this score |
| Multicenter collaboration | — / 3 | Institutions not listed — left out of this score |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 32538845) |
| Free to read | — / 2 | Access not recorded — left out of this score |
| Points | 24 / 56 | Scored on 10 of 20 parts. We have no data for the rest, so they are left out: 24 of the 56 points we could judge it on is 43 out of 100. |
| Total | 43 / 100 | — |
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