Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 27,226–27,250 of 27,380 studies, newest first · page 1090 of 1096.
November 1986 5
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1986-11-18
9/Geriatric Depression Scale (GDS)
48/100 ✓ Peer-reviewed Cognitive tests and assessment Clinical Gerontologist
Full summary, score breakdown and related studies → Original source
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1986-11-01
Prevalence of mental illness in a community nursing home
36/100 ✓ Peer-reviewed Health systems and care delivery The American journal of psychiatry
Key finding: In addition, the majority of demented patients also had noncognitive symptoms such as delusions and hallucinations, and these residents were significantly more likely to have an associated behavioral disorder than were residents without delusions or hallucinations. +1 more finding
Full summary, score breakdown and related studies → Original source
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1986-11-01
Oral tetrahydroaminoacridine in long-term treatment of senile dementia, Alzheimer type
71/100 ✓ Peer-reviewed Clinical trials The New England journal of medicine
Key finding: In the nonblinded first phase of the study, significant improvement occurred in subjects who received the drug, as compared with their pretreatment status, on the global assessment (P = 0.001), the Orientation Test (P = 0.001), and the more sophisticated Names Learning Test (P = 0.001). +2 more findings
Full summary, score breakdown and related studies → Original source
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1986-11-01
The mortality of adults with Down syndrome as a function of age
27/100 ✓ Peer-reviewed Down syndrome and Alzheimer's Mechanisms of ageing and development
Key finding: The differences were not statistically significant.
Full summary, score breakdown and related studies → Original source
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1986-11-01
Incidental subcortical lesions identified on magnetic resonance imaging in the elderly. I. Correlation with age and cerebrovascular risk factors
45/100 ✓ Peer-reviewed Getting a diagnosis Stroke
Key finding: Diabetes, coronary artery diseases, and sex did not play a significant role. +1 more finding
Full summary, score breakdown and related studies → Original source
October 1986 1
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1986-10-01
Hospice approach to the treatment of patients with advanced dementia of the Alzheimer type
48/100 ✓ Peer-reviewed End-of-life care JAMA
Key finding: Preliminary results indicate that the mortality did not increase significantly during the first year of this program, although the extent of medical care was limited in all patients, and 62% were not treated with antibiotics if they developed symptoms of pneumonia or urinary tract infection.
Full summary, score breakdown and related studies → Original source
September 1986 3
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1986-09-01
Training the elderly on the ability factors of spatial orientation and inductive reasoning
66/100 ✓ Peer-reviewed Prevention trials Psychology and aging
Key finding: Significant training effects, at the level of the latent ability constructs, occurred for both spatial orientation and inductive reasoning. +1 more finding
Full summary, score breakdown and related studies → Original source
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1986-09-01
Meta-analysis in clinical trials
52/100 ✓ Peer-reviewed How common it is Controlled Clinical Trials
Key finding: Eight published reviews each reporting results from several related trials lack consistent assessment of homogeneity of treatment effect before pooling. +3 more findings
Full summary, score breakdown and related studies → Original source
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1986-09-01
Seizures and myoclonus in patients with Alzheimer's disease
53/100 ✓ Peer-reviewed Brain tissue and pathology Neurology
Key finding: Eight (10%) had seizures, and eight others (10%) had myoclonus. +3 more findings
Full summary, score breakdown and related studies → Original source
August 1986 1
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1986-08-01
Optic-nerve degeneration in Alzheimer's disease
41/100 ✓ Peer-reviewed Brain scans and imaging The New England journal of medicine
Key finding: In postmortem studies, we found widespread axonal degeneration in the optic nerves of 8 of 10 patients with Alzheimer's disease. +1 more finding
Full summary, score breakdown and related studies → Original source
July 1986 4
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1986-07-01
Predictors of institutionalization among caregivers of patients with Alzheimer's disease
36/100 ✓ Peer-reviewed Caregiving Journal of the American Geriatrics Society
Key finding: The treatment aim of medical care for home-based patients with Alzheimer's disease is to maximize the functioning level of the patient without jeopardizing quality of life for the caregiver.
Full summary, score breakdown and related studies → Original source
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1986-07-01
Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology.
55/100 ✓ Peer-reviewed Disease mechanisms Proceedings of the National Academy of Sciences
A monoclonal antibody to the microtubule-associated protein tau (tau) labeled some neurofibrillary tangles and plaque neurites, the two major locations of paired-helical filaments (PHF), in Alzheimer disease brain.
Full summary, score breakdown and related studies → Original source
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1986-07-01
Leukoencephalopathy in normal and pathologic aging: 2. MRI of brain lucencies
33/100 ✓ Peer-reviewed Brain scans and imaging AJNR. American journal of neuroradiology
Key finding: A pilot study was performed to test the ability of MR to evaluate the brain lucencies shown by CT in Alzheimer disease patients and in normal control subjects. +1 more finding
Full summary, score breakdown and related studies → Original source
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1986-07-01
Positron emission tomography in Alzheimer's disease
53/100 ✓ Peer-reviewed Getting a diagnosis Neurology
Key finding: A significant increase in right/left metabolic asymmetry, particularly in parietal regions, also was seen in mild and moderate groups. +2 more findings
Full summary, score breakdown and related studies → Original source
June 1986 4
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1986-06-01
The neurobiologic consequences of Down syndrome
36/100 ✓ Peer-reviewed Down syndrome and Alzheimer's Brain research bulletin
Key finding: Trisomy of the whole or distal part of human chromosome 21 (HSA 21) (Ts21) results in Down Syndrome (DS), which is characterized in part by mental retardation and associated neurological abnormalities.
Full summary, score breakdown and related studies → Original source
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1986-06-01
The AIDS dementia complex: II. Neuropathology
47/100 ✓ Peer-reviewed Inflammation and the immune system Annals of neurology
Key finding: Most commonly noted was diffuse pallor in the white matter, which in the pathologically milder cases was accompanied by scanty perivascular infiltrates of lymphocytes and brown-pigmented macrophages, and in the most advanced cases by clusters of foamy macrophages and multinucleated cells associated with multifocal rarefaction of the white matter. +2 more findings
Full summary, score breakdown and related studies → Original source
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1986-06-01
Chronic behavioral disorders of human REM sleep: a new category of parasomnia
52/100 ✓ Peer-reviewed Risk factors Sleep
Key finding: There was no associated psychiatric disorder, whereas serious neurologic disorder was closely associated in four cases: olivo-ponto-cerebellar degeneration, Guillain-Barré syndrome, subarachnoid hemorrhage, and an atypical dementia. +4 more findings
Full summary, score breakdown and related studies → Original source
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1986-06-01
The AIDS dementia complex: I. Clinical features
53/100 ✓ Peer-reviewed How common it is Annals of neurology
Key finding: Early motor deficits commonly included ataxia, leg weakness, tremor, and loss of fine-motor coordination, while behavioral disturbances were manifested most commonly as apathy or withdrawal, but occasionally as a frank organic psychosis. +4 more findings
Full summary, score breakdown and related studies → Original source
May 1986 3
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1986-05-01
Immunoregulatory molecules and IL 2 receptors identified in multiple sclerosis brain
36/100 ✓ Peer-reviewed Biomarkers Journal of immunology (Baltimore, Md. : 1950)
Key finding: The results presented here demonstrated that in the MS lesion, there was a marked accumulation of HLA-Dr-positive (Ia-positive) cells. +1 more finding
Full summary, score breakdown and related studies → Original source
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1986-05-01
Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.
51/100 ✓ Peer-reviewed Disease mechanisms Journal of Biological Chemistry
Microtubule-associated protein tau was purified from bovine brain microtubules by either (1) phosphocellulose chromatography, (2) heat treatment at pH 6.4, (3) heat treatment at pH 2.7, (4) heat treatment at pH 2.7 followed by extraction with perchloric acid and precipitation with glycerol, or (5) by precipitation with ammonium sulfate followed by extraction with perchloric acid.
Full summary, score breakdown and related studies → Original source
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1986-05-01
Pharmacologic treatment of agitation associated with dementia
41/100 ✓ Peer-reviewed Disparities Journal of the American Geriatrics Society
Key finding: However, studies done to date indicate that these drugs are effective only for a minority of patients and that side effects frequently make patients worse. +1 more finding
Full summary, score breakdown and related studies → Original source
April 1986 2
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1986-04-01
Dementia: a systematic approach to identifying reversible causes
41/100 ✓ Peer-reviewed Digital health tools Geriatrics
Key finding: The development of FAST is of great importance to clinicians in identifying possibly remediable complications of Alzheimer's disease and distinguishing them from the characteristic progression of the illness. +1 more finding
Full summary, score breakdown and related studies → Original source
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1986-04-01
Hypoxic-ischemic brain lesions found in asphyxiating neonates
27/100 ✓ Peer-reviewed Biomarkers Acta pathologica japonica
Key finding: Neocortical and deep gray matter revealed pyknotic and karyorrhectic neuronal changes; however, in group A, these changes tended to be obscure.
Full summary, score breakdown and related studies → Original source
March 1986 2
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1986-03-01
Why do frontal lobe symptoms predominate in vascular dementia with lacunes?
47/100 ✓ Peer-reviewed Digital health tools Neurology
Key finding: We studied 30 necropsy cases of vascular dementia with a lacunar state. +4 more findings
Full summary, score breakdown and related studies → Original source
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1986-03-01
A white matter disorder in dementia of the Alzheimer type: a pathoanatomical study
40/100 ✓ Peer-reviewed Vascular contributions Annals of neurology
Key finding: Its occurrence is thus neither regularly related to the severity nor to the regional appearance and accentuation of the cortical Alzheimer process and is thus not likely to be just the result of a wallerian degeneration.
Full summary, score breakdown and related studies → Original source
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