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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 27,101–27,125 of 27,380 studies, newest first · page 1085 of 1096.

April 1989 5

  1. 1989-04-01

    Relationship of hearing impairment to dementia and cognitive dysfunction in older adults

    ✓ Peer-reviewed Risk factors JAMA

    Key finding: The prevalence of a hearing loss of 30 dB or greater was significantly higher in cases than in controls (odds ratio, 2.0; 95% confidence interval, 1.2 to 3.4), even when adjusted for potentially confounding variables. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 1989-04-01

    Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein

    ✓ Peer-reviewed Tau biomarkers Cell

    Key finding: The precursors are tyrosine-sulfated, O- and N-glycosylated membrane proteins and have half-lives of 20-30 min in cells. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1989-04-01

    Falls and Parkinson's disease

    ✓ Peer-reviewed Clinical safety Clinical neuropharmacology

    Key finding: It is concluded that falling is a common problem in PD and may cause serious disability.

    Full summary, score breakdown and related studies → Original source

  4. 1989-04-01

    Development of dementing illnesses in an 80-year-old volunteer cohort

    ✓ Peer-reviewed Risk factors Annals of neurology

    Key finding: Risk factors for both dementia and AD were age (over 80) and gender (female); other reported risk factors such as family history, prior head injury, thyroid disease, maternal age, and smoking were not risk factors for AD in this elderly cohort. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 1989-04-01

    Altered expression of genes for amyloid and cytoskeletal proteins in Alzheimer cortex

    ✓ Peer-reviewed Biomarkers Annals of neurology

    Key finding: These findings leave open the possibility that elevated levels of messenger RNA (mRNA) for this protein may contribute to the pathogenesis of AD.

    Full summary, score breakdown and related studies → Original source

March 1989 6

  1. 1989-03-01

    Survival experience of aged hip fracture patients

    ✓ Peer-reviewed Clinical safety American journal of public health

    Key finding: The authors suggest that medical factors that may contribute to patient disorientation be investigated and treated, when possible, in an effort to improve the survival status of hip fracture patients.

    Full summary, score breakdown and related studies → Original source

  2. 1989-03-01

    Synaptic loss in Alzheimer's disease and other dementias

    ✓ Peer-reviewed Disease mechanisms Neurology

    Key finding: All AD patients showed a striking decrease in synaptic staining in the outer half of the molecular layer of the dentate gyrus compared with control brains, where the density of synaptic terminals was uniform throughout.

    Full summary, score breakdown and related studies → Original source

  3. 1989-03-01

    Alzheimer-type neuropathology and clinical symptoms of dementia in mentally retarded people without Down syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's American journal of mental retardation : AJMR

    Key finding: Postmortem morphometric analyses of Bielschowsky stained sections from brains of 70 mentally retarded people without Down syndrome, age 65 and over when they died, indicated Alzheimer-type neuropathology in 22 cases (31%) and a majority with at least presence of some Alzheimer-type lesions. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 1989-03-01

    Divided attention, as measured by dichotic speech performance, in dementia of the Alzheimer type

    ✓ Peer-reviewed Digital health tools Archives of neurology

    Key finding: Although the patients were impaired on both dichotic and monotic tests, significantly greater impairment was seen on the dichotic test. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 1989-03-01

    Linkage of a prion protein missense variant to Gerstmann-Sträussler syndrome

    ✓ Peer-reviewed How common it is Nature

    Key finding: Current diagnostic criteria for Gerstmann-Sträussler syndrome incorporate clinical and neuropathological features, as animal transmission studies can be unreliable. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 1989-03-01

    The immunohistochemical demonstration of subsequences of the precursor of the amyloid A4 protein in senile plaques in Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Neuropathology and applied neurobiology

    Key finding: These findings indicate that the amyloid protein in senile plaques actually contains a larger polypeptide than the A4 protein, and suggest that the intracellular C-terminal part of the precursor may exist in the degenerated neurites seen in senile plaques.

    Full summary, score breakdown and related studies → Original source

February 1989 3

  1. 1989-02-01

    A controlled study of respite service for caregivers of Alzheimer's patients

    ✓ Peer-reviewed Caregiving The Gerontologist

    Key finding: Over 12 months, families with respite care maintained their impaired relative significantly longer in the community (22 days).

    Full summary, score breakdown and related studies → Original source

  2. 1989-02-01

    The pattern of acquisition of plaques and tangles in the brains of patients under 50 years of age with Down's syndrome

    ✓ Peer-reviewed Treatments Journal of the neurological sciences

    Key finding: The form and distribution of senile plaques (SP) and neurofibrillary tangles (NFT) has been examined in the brains of 13 patients with Down's syndrome (DS), aged less than or equal to 50 years, using immunocytochemical and silver staining procedures. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1989-02-01

    Hippocampal specialization of food-storing birds

    ✓ Peer-reviewed Hippocampus size on brain scans Proceedings of the National Academy of Sciences of the United States of America

    Key finding: In a study of 52 individuals belonging to 35 species or subspecies of passerine birds it was shown that the volume of the hippocampal complex relative to brain and body size is significantly larger in species that store food than in species that do not. +1 more finding

    Full summary, score breakdown and related studies → Original source

January 1989 11

  1. 1989-01-01

    Superoxide dismutase activity in Alzheimer's disease: possible mechanism for paired helical filament formation

    ✓ Peer-reviewed Down syndrome and Alzheimer's Brain research

    Key finding: In the present study, SOD-1 activity was significantly elevated by 30% in Alzheimer's cell lines when compared to normal euploid cell lines. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 1989-01-01

    Tau, paired helical filaments and amyloid in the neocortex: a morphometric study of 15 cases with graded intellectual status in aging and senile dementia of Alzheimer type

    ✓ Peer-reviewed Drug development Acta neuropathologica

    Key finding: Tau immunoreactivity was studied in temporal neocortex, area 22, in 15 cases with graded intellectual status and compared with the immunoreactivity observed with an antiserum against paired helical filaments (PHF) and with the density of amyloid revealed by thioflavin S. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1989-01-01

    Patterns of gliosis in Alzheimer's disease and aging cerebrum

    ✓ Peer-reviewed Biomarkers Glia

    Key finding: In conclusion, both AD and aging cerebri show extensive gliosis: AD cortical gliosis has a specific laminar pattern, but there does not appear to be an AD-specific pattern of subcortical gliosis.

    Full summary, score breakdown and related studies → Original source

  4. 1989-01-01

    Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease

    ✓ Peer-reviewed Brain tissue and pathology Brain research

    Key finding: At certain predilection sites, a small number of similar lesions are also present in the brains of the majority of aged non-demented individuals. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 1989-01-01

    Instruments for screening for depression and dementia in a long-term care facility

    ✓ Peer-reviewed Cognitive tests and assessment Journal of the American Geriatrics Society

    Key finding: The diagnostic accuracy of the Mini-Mental State Examination (MMSE) and the Geriatric Depression Scale (GDS) was evaluated against a standardized psychiatric interview. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 1989-01-01

    Beta-amyloid protein probe hybridized to chromosome 9 in 3 Alzheimer disease individuals

    ✓ Peer-reviewed Down syndrome and Alzheimer's Progress in clinical and biological research

    Key finding: We have now obtained additional data which shows significant hybridization to chromosomes 9,20 and 21 for two normal control individuals, a Down syndrome (DS) individual and three AD individuals. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 1989-01-01

    Cerebral extracellular preamyloid deposits in Alzheimer's disease, Down syndrome and nondemented elderly individuals

    ✓ Peer-reviewed Down syndrome and Alzheimer's Progress in clinical and biological research

    Key finding: Using anti-SP28 (a polyclonal antibody to a 28 residue synthetic peptide homologous to the NH2-terminal region of Alzheimer amyloid beta-protein) to investigate the cerebral cortex of 8 Alzheimer and 6 Down patients and 13 nondemented individuals, we found that, besides senile plaques and congophilic vessels, extracellular deposits unrelated to degenerating neurites, tangle-bearing neurons or congophilic vessels were labelled.

    Full summary, score breakdown and related studies → Original source

  8. 1989-01-01

    Molecular genetics of Alzheimer's disease and the amyloid beta peptide precursor gene

    ✓ Peer-reviewed Down syndrome and Alzheimer's Annals of medicine

    Key finding: Employing direct genetic linkage analysis, we have shown that the amyloid gene and the familial Alzheimer's disease gene represent two separate and distinct genetic loci.

    Full summary, score breakdown and related studies → Original source

  9. 1989-01-01

    Elevated levels of an exocrine pancreatic secretory protein in Alzheimer disease brain

    ✓ Peer-reviewed Down syndrome and Alzheimer's Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Quantitative measurements of PTP immunoreactivity in various regions of several AD brains revealed levels varying from 12 to 295 ng/g of tissue (mean, 116 ng/g) compared with 1-11 ng/g of tissue (mean, 5 ng/g) found in comparable areas of control brains. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 1989-01-01

    Dendrites, dementia and the Down syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's Brain & development

    Key finding: The dendritic atrophy seen in childhood continued into adulthood, with a marked decrease in dendritic branching, dendritic length, and spine frequency in elderly adults with the Down syndrome.

    Full summary, score breakdown and related studies → Original source

  11. 1989-01-01

    The pathophysiology of urinary incontinence among institutionalized elderly persons

    ✓ Peer-reviewed Disparities The New England journal of medicine

    Key finding: Detailed urodynamic studies in 94 of the 245 incontinent patients (77 women and 17 men; 38 percent) showed that detrusor overactivity was the predominant cause in 61 percent, with concomitant impaired detrusor contractility present in half these patients. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →