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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 26,626–26,650 of 27,380 studies, newest first · page 1066 of 1096.

August 1994 8

  1. 1994-08-01

    Isolated Cerebral and Cerebellar Mitochondria Produce Free Radicals when Exposed to Elevated Ca2+ and Na+: Implications for Neurodegeneration

    ✓ Peer-reviewed Disease mechanisms Journal of Neurochemistry

    Key finding: Electron paramagnetic resonance studies reported here indicate that intact mitochondria isolated from adult rat cerebral cortex and cerebellum generate extremely reactive hydroxyl (.OH) radicals, plus ascorbyl and other carbon-centered radicals when exposed to 2.5 microM Ca2+, 14 mM Na+, plus elevated ADP under normoxic conditions, circumstances that prevail in the cytoplasm of neurons during excitotoxin-induced neurodegeneration. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 1994-08-01

    Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: identification of phosphorylation sites in tau protein

    ✓ Peer-reviewed Drug development The Biochemical journal

    Key finding: This result contrasts with previous studies of Ser-202 and Ser-396 which are partially phosphorylated in fetal tau, unphosphorylated in adult tau but almost fully phosphorylated in PHF tau.

    Full summary, score breakdown and related studies → Original source

  3. 1994-08-01

    Glycated tau protein in Alzheimer disease: a mechanism for induction of oxidant stress

    ✓ Peer-reviewed Disease mechanisms Proceedings of the National Academy of Sciences of the United States of America

    Key finding: The stability of proteins that constitute the neurofibrillary tangles and senile plaques of Alzheimer disease suggests that they would be ideal substrates for nonenzymatic glycation, a process that occurs over long times, even at normal levels of glucose, ultimately resulting in the formation of advanced glycation end products (AGEs).

    Full summary, score breakdown and related studies → Original source

  4. 1994-08-01

    Evaluation of estrogen treatment in female patients with dementia of the Alzheimer type

    ✓ Peer-reviewed Cognitive tests and assessment Endocrine journal

    Key finding: Fifteen DAT patients with a mean age of (mean +/- SE) 71.9 +/- 2.4 years were treated with 0.625 mg of conjugated equine estrogens orally twice a day for 6 weeks. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 1994-08-01

    Levels of normal and abnormally phosphorylated tau in different cellular and regional compartments of Alzheimer disease and control brains

    ✓ Peer-reviewed Tau biomarkers FEBS letters

    Key finding: In the present study we investigated (i) whether tau is axonal or both axonal and somatodendritic, (ii) whether tau is a marker of Alzheimer neurofibrillary pathology, and (iii) whether the levels of tau in the cytosol (100,000 x g supernate) from AD brain are altered. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 1994-08-01

    Relative abundance of Alzheimer A beta amyloid peptide variants in Alzheimer disease and normal aging

    ✓ Peer-reviewed Risk genes beyond APOE Proceedings of the National Academy of Sciences of the United States of America

    Key finding: We have determined the relative abundance of A beta structural variants present in amyloid from brains of 10 individuals with sporadic AD, 2 individuals with familial AD carrying specific mutations in the Alzheimer amyloid precursor protein gene, and 5 nondemented elderly controls. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 1994-08-01

    Neuropeptide Y immunoreactive neurons in murine trisomy 16 cortical cultures. Plasticity of expression and differentiation

    ✓ Peer-reviewed Down syndrome and Alzheimer's Molecular and chemical neuropathology

    Key finding: The results demonstrate a significant increase in the number of NPY neurons and a stunting in the dendritic arbor of these neurons in trisomic vs euploid cortex. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 1994-08-01

    Estrogen deficiency and risk of Alzheimer's disease in women

    ✓ Peer-reviewed How common it is American journal of epidemiology

    Key finding: The authors explored the possibility that estrogen loss associated with menopause may contribute to the development of Alzheimer's disease by using a case-control study nested within a prospective cohort study. +3 more findings

    Full summary, score breakdown and related studies → Original source

July 1994 9

  1. 1994-07-01

    MDS Cognitive Performance Scale

    ✓ Peer-reviewed How common it is Journal of gerontology

    Key finding: The new CPS provides a functional view of cognitive performance, using readily available MDS data.

    Full summary, score breakdown and related studies → Original source

  2. 1994-07-01

    Parkinson's disease and brain levels of organochlorine pesticides

    ✓ Peer-reviewed Risk factors Annals of neurology

    Key finding: A long-lasting residue of DDT (pp-DDE) was found in the majority of cases of PD and AD, as well as in all the control cases; pp-DDT was significantly more likely to be found in AD controls than the PD cases (Fisher's exact two-tailed, p = 0.04). +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 1994-07-01

    Evidence that production and release of amyloid beta-protein involves the endocytic pathway

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: In addition, deletion of the cytoplasmic domains of beta PP or depletion of potassium in medium, both of which resulted in reduced beta PP internalization, significantly diminished A beta release. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 1994-07-01

    GFAP and astrogliosis

    ✓ Peer-reviewed Biomarkers Brain pathology (Zurich, Switzerland)

    Key finding: The prominence of astroglial reactions in various diseases, the rapidity of the astroglial response and the evolutionary conservation of reactive astrogliosis indicate that reactive astrocytes fulfill important functions of the central nervous system (CNS).

    Full summary, score breakdown and related studies → Original source

  5. 1994-07-01

    Visualization of Aβ42(43) and Aβ40 in senile plaques with end-specific Aβ monoclonals: Evidence that an initially deposited species is Aβ42(43)

    ✓ Peer-reviewed Brain tissue and pathology Neuron

    Full summary, score breakdown and related studies → Original source

  6. 1994-07-01

    Age at onset of Alzheimer's disease: relation to pattern of cognitive dysfunction and rate of decline

    ✓ Peer-reviewed Brain tissue and pathology Neurology

    Key finding: At baseline, early-onset (before age 65) and late-onset groups were mildly and comparably impaired on the modified Mini-Mental State Examination (mMMS) and the Blessed Dementia Rating Scale-Part 1 (BDRS). +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 1994-07-01

    Extrapyramidal signs and psychiatric symptoms predict faster cognitive decline in Alzheimer's disease

    ✓ Peer-reviewed Cognitive tests and assessment Archives of neurology

    Key finding: A cohort of patients was followed up longitudinally and the likelihood of arriving at two cognitive end points was assessed using the Cox proportional hazards model and eight explanatory variables. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 1994-07-01

    Secreted beta-amyloid precursor protein stimulates mitogen-activated protein kinase and enhances tau phosphorylation

    ✓ Peer-reviewed Risk genes beyond APOE Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Little is known, however, about the intracellular cascades that mediate these effects. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 1994-07-01

    Frequency of the apolipoprotein E epsilon 2 allele is diminished in sporadic Alzheimer disease

    ✓ Peer-reviewed Genetics Neuroscience letters

    Key finding: Recent data have demonstrated genetic disequilibrium between inheritance of the apolipoprotein E (apoE) epsilon 4 allele and increased risk of Alzheimer disease. +1 more finding

    Full summary, score breakdown and related studies → Original source

June 1994 8

  1. 1994-06-01

    Electron transport chain defects in Alzheimer's disease brain

    ✓ Peer-reviewed Disease mechanisms Neurology

    Key finding: AD brain mitochondria demonstrated a generalized depression of activity of all electron transport chain complexes.

    Full summary, score breakdown and related studies → Original source

  2. 1994-06-01

    The Natural History of Alzheimer's Disease

    ✓ Peer-reviewed Risk factors Archives of Neurology

    Key finding: Of the 204 patients enrolled in the study, re-review after as many as 5 years of follow-up resulted in a final clinical classification of 188 with probable AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1994-06-01

    Causes of weight loss in a community nursing home

    ✓ Peer-reviewed Health systems and care delivery Journal of the American Geriatrics Society

    Key finding: A single cause of weight loss can be identified in most nursing home residents.

    Full summary, score breakdown and related studies → Original source

  4. 1994-06-01

    Hydrogen peroxide mediates amyloid beta protein toxicity

    ✓ Peer-reviewed Disease mechanisms Cell

    Key finding: Amyloid beta protein (A beta) is a 40-43 amino acid peptide that is associated with plaques in the brains of Alzheimer's patients and is cytotoxic to cultured neurons. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 1994-06-01

    Impact of special care unit for patients with advanced Alzheimer's disease on patients' discomfort and costs

    ✓ Peer-reviewed End-of-life care Journal of the American Geriatrics Society

    Key finding: These results suggest that management of patients with advanced DAT on a DSCU using a palliative care philosophy may result in less patient discomfort and lower costs than management on a TLTC. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 1994-06-01

    Neuropsychological deficits in schizophrenics. Relationship to age, chronicity, and dementia

    ✓ Peer-reviewed Brain tissue and pathology Archives of general psychiatry

    Key finding: We sought to determine whether neuropsychological impairment in schizophrenia is related to current age, age at onset, or duration of illness, and whether the pattern of such impairment can be distinguished from that caused by progressive dementias of Alzheimer's type. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 1994-06-01

    Cognitive correlates of ventricular enlargement and cerebral white matter lesions on magnetic resonance imaging. The Rotterdam Study

    ✓ Peer-reviewed Long-term cohort studies Stroke

    Key finding: Ventricular enlargement and white matter lesions are frequent findings on cerebral magnetic resonance imaging scans of elderly subjects. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 1994-06-01

    Cardiovascular disease and distribution of cognitive function in elderly people: the Rotterdam Study

    ✓ Peer-reviewed Long-term cohort studies BMJ (Clinical research ed.)

    Key finding: Single centre population based cross sectional door to door study. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →