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Cardiovascular disease and distribution of cognitive function in elderly people: the Rotterdam Study
Breteler MM, Claus JJ, Grobbee DE, Hofman A.. BMJ (Clinical research ed.), 1994-06-01
Topic: Risk, prevention and care in population studies
Objective To investigate the distribution of cognitive function in elderly people and to assess the impact of clinical manifestations of atherosclerotic disease on this distribution. Design Single centre population based cross sectional door to door study. Setting Ommoord, a suburb of Rotterdam, the Netherlands.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Breteler, M. M., Claus, J. J., Grobbee, D. E., & Hofman, A. (1994). Cardiovascular disease and distribution of cognitive function in elderly people: the Rotterdam Study. BMJ (Clinical research ed.). https://doi.org/10.1136/bmj.308.6944.1604
Vancouver
Breteler MM, Claus JJ, Grobbee DE, Hofman A. Cardiovascular disease and distribution of cognitive function in elderly people: the Rotterdam Study. BMJ (Clinical research ed.). 1994. doi:10.1136/bmj.308.6944.1604. PMID: 8025427.
BibTeX
@article{breteler1994-8025427,
author = {Breteler, M. M. and Claus, J. J. and Grobbee, D. E. and Hofman, A.},
title = {{Cardiovascular disease and distribution of cognitive function in elderly people: the Rotterdam Study}},
journal = {BMJ (Clinical research ed.)},
year = {1994},
doi = {10.1136/bmj.308.6944.1604},
pmid = {8025427},
url = {https://doi.org/10.1136/bmj.308.6944.1604}
}
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Key findings
- Design Single centre population based cross sectional door to door study.
- Setting Ommoord, a suburb of Rotterdam, the Netherlands.
- Subjects 4971 subjects aged 55 to 94 years.
- Main outcome measure Cognitive function as measured by the mini mental state examination.
Why it matters
This study examined the distribution of cognitive function in 4,971 older people and whether signs of atherosclerotic disease affect it. It looked at links between cardiovascular disease and thinking ability, which may inform understanding of risk factors but does not test any treatment.
Study details
- Participants4,971
- Evidence strengthLow
How this study scored 57/100
Published in a leading specialty journal. Scored zero for study design, effect reported and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 9 / 10 | Tier 2 — leading specialty journal (BMJ (Clinical research ed.)) |
| Journal's citation record | 4 / 4 | BMJ: journal h-index 608 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 1994 — older than 20 years, still counted |
| Sample size | 3 / 4 | 4,971 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 6 / 7 | Cited 544 times (OpenAlex, 2026-10-10) |
| Citations per year | 3 / 5 | 16.0 citations a year over 34 year(s) since 1994 |
| Impact for its field and year | 4 / 6 | Cited 9.1× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 3 / 6 | Cited by 25 other studies in this library |
| Still being cited | 2 / 4 | Cited 23 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 4 / 4 | Last-listed author Albert Hofman: h-index 207 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | Erasmus MC: institution h-index 1,321 (OpenAlex) |
| Multi-centre collaboration | 1 / 3 | OpenAlex lists 2 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 8025427) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 57 / 100 | — |
What each of these 20 components measures, and what this score is not →
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