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Soluble Amyloid β Peptide Concentration as a Predictor of Synaptic Change in Alzheimer's Disease
Lih‐Fen Lue, Yu‐Min Kuo, Alex E. Roher, Libuse Brachova, Yong Shen, Lucia I. Sue, Thomas G. Beach, Janice H. Kurth, Russell E. Rydel, Joseph Rogers. American Journal Of Pathology, 1999-09-01
Topic: Amyloid, tau and blood-test diagnosis
We do not hold a plain-English summary of this study yet. Use the links to the original below for its abstract and findings.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Lue, L., Kuo, Y., Roher, A. E., Brachova, L., Shen, Y., Sue, L. I., et al. (1999). Soluble Amyloid β Peptide Concentration as a Predictor of Synaptic Change in Alzheimer's Disease. American Journal Of Pathology. https://doi.org/10.1016/s0002-9440(10)65184-x
Vancouver
Lue L, Kuo Y, Roher AE, Brachova L, Shen Y, Sue LI, et al. Soluble Amyloid β Peptide Concentration as a Predictor of Synaptic Change in Alzheimer's Disease. American Journal Of Pathology. 1999. doi:10.1016/s0002-9440(10)65184-x. PMID: 10487842.
BibTeX
@article{lue1999-10487842,
author = {Lue, Lih‐Fen and Kuo, Yu‐Min and Roher, Alex E. and Brachova, Libuse and Shen, Yong and Sue, Lucia I. and Beach, Thomas G. and Kurth, Janice H. and Rydel, Russell E. and Rogers, Joseph},
title = {{Soluble Amyloid β Peptide Concentration as a Predictor of Synaptic Change in Alzheimer's Disease}},
journal = {American Journal Of Pathology},
year = {1999},
doi = {10.1016/s0002-9440(10)65184-x},
pmid = {10487842},
url = {https://doi.org/10.1016/s0002-9440(10)65184-x}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record names 10 authors; APA and Vancouver show the first six, BibTeX and the downloads carry all of them. Check the citation against the original before you use it.
Why it matters
Examines soluble amyloid β peptide concentration as a predictor of synaptic change in Alzheimer's disease.
How this study scored 51/100
Published in a peer-reviewed journal. Scored zero for study design, sample size, effect reported, studied in people and randomised / blinded because the record does not state it. We have no data on strength of evidence, so that was left out: it earned 48 of the 95 points we could judge it on, which is 51 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (American Journal Of Pathology) |
| Journal's citation record | 3 / 4 | American Journal Of Pathology: journal h-index 328 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | — / 5 | No evidence rating recorded — left out of this score |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 1999 — older than 20 years, still counted |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 7 / 7 | Cited 1,533 times (OpenAlex, 2026-10-10) |
| Citations per year | 5 / 5 | 52.9 citations a year over 29 year(s) since 1999 |
| Impact for its field and year | 4 / 6 | Cited 17.4× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 3 / 4 | Cited 64 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 3 / 4 | Last-listed author Joseph Rogers: h-index 61 (OpenAlex, whole career) |
| Institution's track record | 0 / 3 | Banner Sun Health Research Institute: institution h-index 285 (OpenAlex) |
| Multi-centre collaboration | 1 / 3 | OpenAlex lists 2 institution(s) in 2 countries |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 10487842) |
| Free to read | 2 / 2 | Free to read |
| Points | 48 / 95 | Scored on 19 of 20 parts. We have no data for the rest, so they are left out: 48 of the 95 points we could judge it on is 51 out of 100. |
| Total | 51 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.1016/s0002-9440(10)65184-x
- PubMed: 10487842
- Original source →
- Free full text: American Journal Of Pathology →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
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