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Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.

Highest usefulness score first. Studies without a score come last.

  1. One-year brain atrophy evident in healthy aging

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. The Journal of neuroscience : the official journal of the Society for Neuroscience 2009-12-01 Brain scans and imaging

    An accurate description of changes in the brain in healthy aging is needed to understand the basis of age-related changes in cognitive function.

  2. A longitudinal study of the effects of lithium treatment on prefrontal and subgenual prefrontal gray matter volume in treatment-responsive bipolar disorder patients

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. The Journal of clinical psychiatry 2009-04-21 Drug development

    The increase in gray matter volume in these areas, which various neuroimaging and postmortem neuropathology studies have implicated in the neuropathophysiology of bipolar disorder, suggests that the observed effects may be linked to clinical response.

  3. Utility of different MR modalities in mild cognitive impairment and its use as a predictor of conversion to probable dementia

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Academic radiology 2008-09-01 Biomarkers

    Rationale and objectives Mild cognitive impairment has been regarded as a pre-Alzheimer condition, but some patients do not develop dementia.

  4. Cognitive executive function in Down's syndrome

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. The British journal of clinical psychology 2006-03-01 Down syndrome and Alzheimer's

    It is suggested that impaired executive function in Down's syndrome is due to abnormal development of the prefrontal cortex in Down's syndrome.

  5. Free testosterone and risk for Alzheimer disease in older men

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Neurology 2004-01-27 Prevention and risk

    Diagnosis of AD was associated inversely with FTI by itself and after adjustments for age, education, smoking status, body mass index, diabetes, any cancer diagnoses, and hormone supplements.

  6. Prediction of cognitive decline in normal elderly subjects with 2-[(18)F]fluoro-2-deoxy-D-glucose/poitron-emission tomography (FDG/PET)

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2001-08-28 Genetics

    Neuropathology studies show that patients with mild cognitive impairment (MCI) and Alzheimer's disease typically have lesions of the entorhinal cortex (EC), hippocampus (Hip), and temporal neocortex.

  7. Hearing impairment and cognitive decline in senile dementia of the Alzheimer's type

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Journal of the American Geriatrics Society 1986-03-01 Risk factors

    Hearing impairment has been hypothesized as contributing to symptoms of dementia.

  8. Disease specific and nonspecific metabolic brain networks in behavioral variant of frontotemporal dementia

    ✓ Peer-reviewed alzhub usefulness score 58 out of 100. Human brain mapping 2022-11-05 Brain scans and imaging

    Behavioral variant of frontotemporal dementia (bvFTD) is common among young-onset dementia patients.

  9. [Cognitive impairment in patients with cardiovascular risk: DECOG study]

    ✓ Peer-reviewed alzhub usefulness score 58 out of 100. Semergen 2021-04-15 Risk factors

    Data from a total of 458 patients were collected.

  10. Diffusion MRI of Gray Matter Microstructural Profiles in Healthy Aging

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Neuroscience and biobehavioral reviews 2026-08-06 Prevention trials

    Diffusion-weighted imaging (DWI) is a non-invasive magnetic resonance imaging (MRI) acquisition technique that can provide detailed information about brain microstructure.

  11. Clinical validity of IntelliSpace Cognition digital assessment platform in mild cognitive impairment

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Frontiers in psychology 2024-12-30 Cognitive tests and assessment

    We evaluated a digital cognitive assessment platform, Philips IntelliSpace Cognition, in a case-control study of patients diagnosed with mild cognitive impairment (MCI) and cognitively normal (CN) older adults.

  12. Factors associated with cognitive reserve according to education level

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2024-09-10 Risk factors

    In the low-education group, low literacy, long sleep duration(>8 h/day), and diabetes were negatively associated with CR, whereas cognitive and physical activity were positively associated with CR.

  13. Cognitive modeling of the Mnemonic Similarity Task as a digital biomarker for Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2024-09-06 Cognitive tests and assessment

    A MPT model of the MST can detect individuals with AD prior to cognitive decline, making it a potentially useful tool for screening and monitoring older adults during the asymptomatic phase of AD.

  14. Cognitive reserve, cortisol, and Alzheimer's disease biomarkers: A memory clinic study

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2024-06-04 Risk factors

    Higher CRI scores were associated with better cognition.

  15. A remote digital memory composite to detect cognitive impairment in memory clinic samples in unsupervised settings using mobile devices

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. NPJ digital medicine 2024-03-26 Cognitive tests and assessment

    Remote monitoring of cognition holds the promise to facilitate case-finding in clinical care and the individual detection of cognitive impairment in clinical and research settings.

  16. Safety and efficacy of acupuncture for mild cognitive impairment: a study protocol for clinical study

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Frontiers in neurology 2024-03-15 Cognitive tests and assessment

    The findings of this protocol will provide information regarding the effects of acupuncture on MCI.

  17. Associations between sleep-behavioral traits and healthspan: A one-sample Mendelian randomization study based on 388,909 participants of the UK-Biobank

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Journal of affective disorders 2024-01-21 Risk factors

    In IPTW, we observed a decreased risk of terminated healthspan for healthy sleep behaviors such as 'sleep duration 7-8h/d' (Hazard ratio, HR = 0.93; 95 % confidence interval, CI: 0.92-0.96; P < 0.001); 'morningness' (HR = 0.95; 95%CI: 0.93-0.98; P < 0.01); 'napping' (HR = 0.93; 95%CI: 0.91-0.94; P < 0.001); 'easy getting up from bed' (HR = 0.91; 95%CI: 0.88-0.93; P < 0.001); and, 'never/rarely experience sleeplessness/insomnia' (HR = 0.94; 95%CI: 0.92-0.96; P < 0.001).

  18. Cognitive change in prevalent and incident hearing loss: The Maastricht Aging Study

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2024-01-18 Risk factors

    Participants with prevalent and incident HL showed a faster decline in verbal memory, information processing speed, and executive function than participants without HL.

  19. Sleep duration and brain MRI measures: Results from the SOL-INCA MRI study

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2023-09-29 Risk factors

    The final analytic sample included n = 2334 participants.

  20. Altered within- and between-network functional connectivity in atypical Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Brain communications 2023-06-14 Brain scans and imaging

    Reduced within-network connectivity was observed in the language network in both phenotypes, with stronger evidence of reductions in logopenic progressive aphasia compared to controls.

  21. Brain reserve contributes to distinguishing preclinical Alzheimer's stages 1 and 2

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Alzheimer's research & therapy 2023-02-28 Risk factors

    In asymptomatic individuals, brain volumes of hippocampal subfields and of the parahippocampal cortex were numerically larger in stage 1 compared to HCs, whereas the opposite was the case in individuals with SCD.

  22. Association Between Sensory Impairment and Dementia: The Roles of Social Network and Leisure Activity

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Journal of Alzheimer's disease : JAD 2023 Risk factors

    Dual impairment, but not single impairment in hearing and vision was associated with a higher risk of dementia (HR: 1.62, 95% CI: 1.16 to 2.27).

  23. Longitudinal associations between sleep duration and cognitive impairment in Chinese elderly

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Frontiers in aging neuroscience 2022-11-17 Risk factors

    The empirical study showed a U-shaped relationship between sleep duration and increased risk of cognitive impairment.

  24. The Laterality of Early Age-Related Hearing Loss and Brain β-Amyloid

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 2022-03-01 Risk factors

    Mean age ± standard deviation was 64.3 ± 3.5 years.

  25. Effects of Cognitive Reserve in Alzheimer's Disease and Cognitively Unimpaired Individuals

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Frontiers in aging neuroscience 2022-02-07 Risk factors

    The concept of cognitive reserve (CR) has been proposed as a protective factor that modifies the effect of brain pathology on cognitive performance.

From across this topic

10 of the 1,533 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

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