Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.

Highest usefulness score first. Studies without a score come last.

  1. Adiposity impacts cognitive function in Asian populations: an epidemiological and Mendelian Randomization study

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. The Lancet regional health. Western Pacific 2023-02-14 Cognitive tests and assessment

    In univariate analysis, all 29 adiposity and metabolic measures assessed were associated with ' g ' at P < 0.05.

  2. Artificial Intelligence in Health Care: Bibliometric Analysis

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Journal of medical Internet research 2020-07-29 Digital health tools

    This analysis provides a comprehensive overview of the AI-related research conducted in the field of health care, which helps researchers, policy makers, and practitioners better understand the development of health care-related AI research and possible practice implications.

  3. Longitudinal ComBat: A method for harmonizing longitudinal multi-scanner imaging data

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. NeuroImage 2020-07-05 Brain scans and imaging

    While aggregation of neuroimaging datasets from multiple sites and scanners can yield increased statistical power, it also presents challenges due to systematic scanner effects.

  4. Associations between cerebrovascular risk factors and parkinson disease

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Annals of neurology 2019-08-29 Digital health tools

    Cerebrovascular risk factors are associated with Parkinson disease, an effect comparable to their association with Alzheimer disease.

  5. Association Between Sensory Impairment and Dementia in Older Adults: Evidence from China

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Journal of the American Geriatrics Society 2018-01-10 Risk factors

    Sensory impairments are associated with greater risk of dementia in Chinese older adults.

  6. Association Between Oral Health and Cognitive Status: A Systematic Review

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Journal of the American Geriatrics Society 2016-04-01 Digital health tools

    It is unclear how or whether oral health and cognitive status are related.

  7. Baseline neuropsychiatric symptoms and the risk of incident mild cognitive impairment: a population-based study

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. The American journal of psychiatry 2014-05-01 Clinical safety

    An increased incidence of mild cognitive impairment was observed in community-dwelling elderly adults who had nonpsychotic psychiatric symptoms at baseline.

  8. Recommendations for optimal ICD codes to study neurologic conditions: a systematic review

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Neurology 2012-08-22 Digital health tools

    Thirty full-text articles met the eligibility criteria.

  9. Red blood cell ω-3 fatty acid levels and markers of accelerated brain aging

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Neurology 2012-02-01 Prevention trials

    Lower RBC DHA levels are associated with smaller brain volumes and a "vascular" pattern of cognitive impairment even in persons free of clinical dementia.

  10. Neuropathological correlates of dementia in over-80-year-old brain donors from the population-based Cambridge city over-75s cohort (CC75C) study

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Journal of Alzheimer's disease : JAD 2009-01-01 End-of-life care

    Key neuropathological changes associated with late-onset dementia are not fully understood.

  11. Neuropsychiatric manifestations in mild cognitive impairment: a systematic review of the literature

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Dementia and geriatric cognitive disorders 2007-12-14 Clinical safety

    Neuropsychiatric symptoms are common features of MCI.

  12. Frailty is associated with incident Alzheimer's disease and cognitive decline in the elderly

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Psychosomatic medicine 2007-06-07 Long-term cohort studies

    Increasing frailty is associated with incident AD and the rate of cognitive decline in older persons.

  13. How common are the "common" neurologic disorders?

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Neurology 2007-01-01 How common it is

    Using the best available data, our survey of a limited number of disorders shows that the burden of neurologic illness affects many millions of people in the United States.

  14. Depression as a risk factor for Alzheimer disease: the MIRAGE Study

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Archives of neurology 2003-05-01 Risk factors

    Depression symptoms before the onset of AD are associated with the development of AD, even in families where first depression symptoms occurred more than 25 years before the onset of AD.

  15. Midlife sleep characteristics and Alzheimer's disease biomarkers 20 years later

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2026-04 Biomarkers

    After multivariable adjustment, longer sleep duration was associated with lower Aβ42/40, poor sleep quality with higher NfL, daytime sleepiness with both lower Aβ42/40 and higher NfL, and insomnia symptoms with higher SPARE-AD.

  16. Unveiling 30 years of research on speech biomarker of dementia using text mining

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Digital health 2025-07-29 Cognitive tests and assessment

    Our analysis yielded three major a marked acceleration in research activity since 2020, a convergence of clinical needs with technological advancements, and the inherently interdisciplinary nature of this field.

  17. Early detection of dementia through retinal imaging and trustworthy AI

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. NPJ digital medicine 2024-10-20 Brain scans and imaging

    Alzheimer's disease (AD) is a global healthcare challenge lacking a simple and affordable detection method.

  18. Deep learning-based amyloid PET harmonization to predict cognitive decline in non-demented elderly

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Radiology advances 2024-08-06 Brain scans and imaging

    DL-ADprob was independently prognostic in both ADNI-MCI (P < .001) and HABS-CU (P = .048) sets.

  19. Sleep disturbances, cognitive decline, and AD biomarkers alterations in early Parkinson's disease

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Annals of clinical and translational neurology 2024-05-19 Risk factors

    Baseline pRBD was associated with faster decline in global cognition and all cognitive domains, including verbal episodic memory, visuospatial ability, executive function, language, and processing speed.

  20. Atrial Fibrillation and Dementia: Pathophysiological Mechanisms and Clinical Implications

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Biomolecules 2024-04-08 Risk factors

    Numerous longitudinal studies suggest a strong association between cardiovascular risk factors and cognitive impairment.

  21. Postural Control Characteristics in Alzheimer's Disease, Dementia With Lewy Bodies, and Vascular Dementia

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. The journals of gerontology. Series A, Biological sciences and medical sciences 2024-04-01 Cognitive tests and assessment

    The study included 1 789 participants (1 206 with AD, 111 with DLB, 49 with VaD, and 423 with NC).

  22. Safety, tolerability, and efficacy estimate of evoked gamma oscillation in mild to moderate Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Frontiers in neurology 2024-03-06 Treatments

    Our results demonstrate that 1-h daily treatment with Cognito's Evoked Gamma Therapy System (CogTx-001) was safe and well-tolerated and demonstrated potential clinical benefits in mild to moderate AD.

  23. Assessment of Mild Cognitive Impairment Using CogEvo: A Computerized Cognitive Function Assessment Tool

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Journal of primary care & community health 2024 Cognitive tests and assessment

    Both total CogEvo and MMSE scores significantly decreased with age.

  24. Longitudinal trajectories of cognitive reserve in hypometabolic subtypes of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Neurobiology of aging 2023-12-19 Risk factors

    Previous studies have demonstrated resilience to AD-related neuropathology in a form of cognitive reserve (CR).

  25. Physical activity, biomarkers of brain pathologies and dementia risk: Results from the Memento clinical cohort

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2023-07-08 Biomarkers

    Physical activity moderated the association between MTA and plasma Aβ42/40 level and increased dementia risk.

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