Research answers, by question

These pages describe what published research says. They are not medical advice. Counts are as of 2026-11-08.

• MCI to dementia conversion rate 1,393 matching studies

  How often mild cognitive impairment (MCI) progresses to dementia is one of the most-asked questions in Alzheimer's research. This page shows what the library holds on it.

• Lecanemab (Leqembi) 286 matching studies

  Lecanemab, sold as Leqembi, is an anti-amyloid antibody approved for early Alzheimer's disease. This page shows what the library holds on it.

• Donanemab (Kisunla) 166 matching studies

  Donanemab, sold as Kisunla, is an anti-amyloid antibody approved for early Alzheimer's disease. This page shows what the library holds on it.

• Aducanumab (Aduhelm) 211 matching studies

  Aducanumab, sold as Aduhelm, was the first anti-amyloid antibody approved in the United States and was later withdrawn from the market. This page shows what the library holds on it.

• APOE4 and Alzheimer's risk 1,711 matching studies

  APOE ε4 is the most common genetic risk factor for late-onset Alzheimer's disease. This page shows what the library holds on carrying one or two copies.

• Amyloid PET scan results 1,354 matching studies

  An amyloid PET scan shows whether amyloid plaques have built up in the brain. This page shows what the library holds on reading one.

• Blood tests for Alzheimer's 2,002 matching studies

  Blood tests that measure Alzheimer's proteins in plasma are moving from research into clinics. This page shows what the library holds on how well they work.

• p-tau217 565 matching studies

  p-tau217 is the blood marker most of the newest Alzheimer's diagnostic papers focus on. This page shows what the library holds on it.

• Caregiver support 1,644 matching studies

  Most people with dementia are cared for by family. This page shows what the library holds on support for the people doing that work.

• Alzheimer's clinical trials 3,061 matching studies

  Clinical trials are how a treatment is tested in people. This page explains the phases, counts what the library holds, and points to the registry where trials are listed.

• ARIA: brain swelling and bleeds 351 matching studies

  ARIA is the main side effect of the anti-amyloid antibodies. This page shows what the library holds on how often it happens and to whom.

• Donepezil and memantine 647 matching studies

  Donepezil, rivastigmine, galantamine and memantine treat the symptoms of Alzheimer's rather than its cause. This page shows what the library holds on them.

• Semaglutide and GLP-1 drugs 342 matching studies

  GLP-1 receptor agonists, the diabetes and weight-loss drugs, are being tested for Alzheimer's. This page shows what the library holds.

• Hearing loss and dementia 293 matching studies

  Hearing loss in mid and later life is counted among the modifiable risk factors for dementia. This page shows what the library holds on the link and on hearing aids.

• Sleep and Alzheimer's 967 matching studies

  Sleep is tied to Alzheimer's in both directions: poor sleep may raise risk, and the disease disrupts sleep. This page shows what the library holds.

• Exercise and dementia 1,075 matching studies

  Physical activity is one of the most-studied ways to lower dementia risk. This page shows what the library holds on it, trials and cohort studies alike.

• Diet and Alzheimer's 1,803 matching studies

  Diet is studied both as a risk factor for dementia and as an intervention. This page shows what the library holds on eating patterns, nutrients and supplements.

• Is Alzheimer's hereditary? 2,309 matching studies

  Alzheimer's runs in families in two very different ways: a rare inherited form that starts early, and a common form where genes raise risk without deciding it. This page shows what the library holds.

• Down syndrome and Alzheimer's 826 matching studies

  People with Down syndrome carry an extra copy of the gene that makes amyloid, and almost all develop Alzheimer's pathology by middle age. This page shows what the library holds.

• Lewy body dementia vs Alzheimer's 1,318 matching studies

  Dementia with Lewy bodies is the second most common degenerative dementia after Alzheimer's and is often mistaken for it. This page shows what the library holds on telling them apart.

• Frontotemporal dementia 1,636 matching studies

  Frontotemporal dementia usually starts earlier than Alzheimer's and changes behaviour or language before memory. This page shows what the library holds on it.

• Tau PET scans 591 matching studies

  Tau PET shows where tangles of tau protein have spread in the brain, which tracks symptoms more closely than amyloid. This page shows what the library holds.

• Life expectancy after diagnosis 1,699 matching studies

  How long people live after a diagnosis of Alzheimer's varies widely. This page shows what the library holds on survival and what shapes it.

• Agitation in dementia 798 matching studies

  Agitation is among the hardest parts of dementia for families. This page shows what the library holds on how often it occurs and what has been tested against it.

• Diabetes and Alzheimer's 1,762 matching studies

  Type 2 diabetes raises the risk of dementia, and the brain's own handling of insulin is disturbed in Alzheimer's. This page shows what the library holds on the link.