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Selectively Disrupted Functional Connectivity Networks in Type 2 Diabetes Mellitus
Yaojing Chen, Zhen Liu, Junying Zhang, Guihua Tian, Linzi Li, Sisi Zhang, Xin Li, Kewei Chen et al.. Frontiers in aging neuroscience, 2015-12-11
Topic: Brain imaging, connectivity and assessment
We found that patients with T2DM exhibited cognitive function declines and functional connectivity disruptions within the default mode network, left frontal parietal network, and sensorimotor network. More importantly, the fasting glucose level was correlated with abnormal functional connectivity. These findings could help to understand the neural mechanisms of cognitive impairments in T2DM and provide potential neuroimaging biomarkers that may be used for early diagnosis and intervention in cognitive decline.
Key findings
- We found that patients with T2DM exhibited cognitive function declines and functional connectivity disruptions within the default mode network, left frontal parietal network, and sensorimotor network.
- More importantly, the fasting glucose level was correlated with abnormal functional connectivity.
- These findings could help to understand the neural mechanisms of cognitive impairments in T2DM and provide potential neuroimaging biomarkers that may be used for early diagnosis and intervention in cognitive decline.
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Study details
- Participants37
- Evidence strengthLow
How this study scored 45/100
Published in a peer-reviewed journal. Scored zero for study design, effect reported and randomised / blinded because the record does not state it. We have no data on journal's citation record, times cited, citations per year, impact for its field and year, cited by studies here, still being cited, senior author's track record, institution's track record, multi-centre collaboration and free to read, so those were left out: it earned 25 of the 56 points we could judge it on, which is 45 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Frontiers in aging neuroscience) |
| Journal's citation record | — / 4 | No journal record from OpenAlex — left out of this score |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 2015 — within 20 year(s) of the newest study here |
| Sample size | 1 / 4 | 37 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | — / 7 | No citation count (not found in OpenAlex) — left out of this score |
| Citations per year | — / 5 | No citation count or no year — left out of this score |
| Impact for its field and year | — / 6 | No field-weighted citation impact (OpenAlex has none yet) — left out of this score |
| Cited by studies here | — / 6 | Not yet checked against this library's citation graph — left out of this score |
| Still being cited | — / 4 | No yearly citation counts — left out of this score |
| Senior author's track record | — / 4 | Senior author's record not available — left out of this score |
| Institution's track record | — / 3 | No institution listed in OpenAlex — left out of this score |
| Multi-centre collaboration | — / 3 | Institutions not listed — left out of this score |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 26696885) |
| Free to read | — / 2 | Access not recorded — left out of this score |
| Points | 25 / 56 | Scored on 10 of 20 parts. We have no data for the rest, so they are left out: 25 of the 56 points we could judge it on is 45 out of 100. |
| Total | 45 / 100 | — |
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Read the original
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Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.
APA 7th
Chen, Y., Liu, Z., Zhang, J., Tian, G., Li, L., Zhang, S., et al. (2015). Selectively Disrupted Functional Connectivity Networks in Type 2 Diabetes Mellitus. Frontiers in aging neuroscience. https://doi.org/10.3389/fnagi.2015.00233
Vancouver
Chen Y, Liu Z, Zhang J, Tian G, Li L, Zhang S, et al. Selectively Disrupted Functional Connectivity Networks in Type 2 Diabetes Mellitus. Frontiers in aging neuroscience. 2015. doi:10.3389/fnagi.2015.00233. PMID: 26696885.
BibTeX
@article{chen2015-26696885,
author = {Chen, Yaojing and Liu, Zhen and Zhang, Junying and Tian, Guihua and Li, Linzi and Zhang, Sisi and Li, Xin and Chen, Kewei and others},
title = {{Selectively Disrupted Functional Connectivity Networks in Type 2 Diabetes Mellitus}},
journal = {Frontiers in aging neuroscience},
year = {2015},
doi = {10.3389/fnagi.2015.00233},
pmid = {26696885},
url = {https://doi.org/10.3389/fnagi.2015.00233}
}
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