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You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.

Highest usefulness score first. Studies without a score come last.

  1. White matter changes in mild cognitive impairment and AD: A diffusion tensor imaging study

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Neurobiology of aging 2005-07-07 Brain scans and imaging

    Diffusion tensor imaging (DTI) can detect, in vivo, the directionality of molecular diffusion and estimate the microstructural integrity of white matter (WM) tracts.

  2. Focal decline of cortical thickness in Alzheimer's disease identified by computational neuroanatomy

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Cerebral cortex (New York, N.Y. : 1991) 2004-11-10 Brain scans and imaging

    Alzheimer's disease (AD) is characterized by a heterogeneous distribution of pathological changes throughout the brain.

  3. Motor cortex hyperexcitability to transcranial magnetic stimulation in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Journal of neurology, neurosurgery, and psychiatry 2004-04-01 Treatments

    The change in threshold did not seem to correlate with dysfunction of inhibitory intracortical cholinergic and GABAergic circuits, nor with the central cholinergic activity.

  4. Influence of executive function on locomotor function: divided attention increases gait variability in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Journal of the American Geriatrics Society 2003-11-01 Digital health tools

    Divided attention markedly impairs the ability of patients with AD to regulate the stride-to-stride variations in gait timing.

  5. Synucleinopathy pathology and REM sleep behavior disorder plus dementia or parkinsonism

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Neurology 2003-07-08 Risk factors

    Fifteen cases were identified (14 men). All had clear histories of dream enactment behavior, and 10 had RBD confirmed by polysomnography.

  6. White matter damage in Alzheimer's disease assessed in vivo using diffusion tensor magnetic resonance imaging

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Journal of neurology, neurosurgery, and psychiatry 2002-06-01 Brain scans and imaging

    White matter changes in patients with Alzheimer's disease are likely to be secondary to wallerian degeneration of fibre tracts due to neuronal loss in cortical associative areas.

  7. Serum lipoprotein levels, statin use, and cognitive function in older women

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Archives of neurology 2002-03-01 Drug development

    High LDL and total cholesterol levels are associated with cognitive impairment, and lowering these lipoprotein levels may be a strategy for preventing impairment.

  8. Sundowning and circadian rhythms in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. The American journal of psychiatry 2001-05-01 Risk factors

    These data indicate that Alzheimer's disease causes disturbances of circadian rhythms and that sundowning is related to a phase delay of body temperature caused by Alzheimer's disease.

  9. Neurologists' use of ICD-9CM codes for dementia

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Neurology 2001-05-01 Digital health tools

    Neurologists' use of ICD-9CM codes in a sample of 181 consecutive, new patients evaluated for dementia by 48 of all 49 neurologists from the Rochester, NY, area over a 1-year period was examined.

  10. Effects of individualized versus classical "relaxation" music on the frequency of agitation in elderly persons with Alzheimer's disease and related disorders

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. International psychogeriatrics 2000-03-01 Health systems and care delivery

    Confusion and agitation in elderly patients are crucial problems.

  11. Indirect bright light improves circadian rest-activity rhythm disturbances in demented patients

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Biological psychiatry 1997-05-01 Risk factors

    Light is known to be an important modulator of circadian rhythms.

  12. Frontal behavioral inventory: diagnostic criteria for frontal lobe dementia

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 1997-02-01 Getting a diagnosis

    The FBI appears to be a useful diagnostic instrument and a method to operate the behavioral criteria of FLD.

  13. Association of premorbid intellectual function with cerebral metabolism in Alzheimer's disease: implications for the cognitive reserve hypothesis

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. American Journal of Psychiatry 1997-02-01 Brain scans and imaging

    After the authors controlled for demographic characteristics and dementia severity, both estimates of premorbid intellectual ability were inversely correlated with cerebral metabolism in the prefrontal, pre-motor, and left superior parietal association regions.

  14. An Inventory to Assess Activities of Daily Living for Clinical Trials in Alzheimerʼs Disease

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Alzheimer Disease & Associated Disorders 1997-01-01 Cognitive tests and assessment

    We developed a set of informant-based items describing performance of activities of daily living (ADL) by patients with Alzheimer's disease (AD) to identify which ADL are useful for assessment of patients in clinical trials.

  15. Circadian rest-activity rhythm disturbances in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Biological psychiatry 1996-08-01 Risk factors

    Previous studies showed circadian rhythm disturbances in patients with Alzheimer's disease.

  16. The Predictive Value of Cerebrospinal Fluid Dynamic Tests in Patients With the Idiopathic Adult Hydrocephalus Syndrome

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Archives of Neurology 1995-08-01 Digital health tools

    Gait was improved in 25 (72%) of the 35 patients, whereas the Bartel index remained unchanged.

  17. Clinical and neuropathological correlates of depression in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Psychological medicine 1992-11-01 Risk factors

    Depressive symptoms have been reported in patients with mild to moderate Alzheimer's disease (AD).

  18. Detection and Staging of Dementia in Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Archives of Neurology 1992-05-01 Risk factors

    Our earlier studies using the Consortium to Establish a Registry of Alzheimer's Disease neuropsychological battery showed that delayed recall was a highly sensitive indicator of early Alzheimer's disease.

  19. The Neuropathologic Basis of Different Clinical Subgroups of Parkinson's Disease

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Journal of Neuropathology & Experimental Neurology 1991-11-01 Risk factors

    Clinical and neuropathologic data in 45 patients with Parkinson's disease (PD) were compared.

  20. Marked cerebrospinal fluid void: indicator of successful shunt in patients with suspected normal-pressure hydrocephalus

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Radiology 1991-02-01 Digital health tools

    The authors blindly reviewed the charts of 20 patients with normal-pressure hydrocephalus (a disease of unknown cause characterized radiologically as chronic communicating hydrocephalus and clinically by gait apraxia, dementia, and incontinence) who had undergone creation of a ventriculoperitoneal shunt.

  21. Subcortical Arteriosclerotic Encephalopathy (Binswanger's Disease)

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Archives of Neurology 1985-10-01 Digital health tools

    Twenty-three elderly patients were found to have a consistent pattern of leukoencephalopathy by computed tomography and nuclear magnetic resonance imaging.

  22. The Galveston Orientation and Amnesia Test. A practical scale to assess cognition after head injury

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. The Journal of nervous and mental disease 1979-11-01 Brain scans and imaging

    The Galveston Orientation and Amnesia Test (GOAT) was developed to evaluate cognition serially during the subacute stage of recovery from closed head injury.

  23. Relationships Among Hearing, Auditory Processing, and Cognition: A Study of Older Adults

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Audiology research 2026-08-07 Risk factors

    DSI emerged as a significant predictor across both MoCA and CBB, surpassing the predictive power of both types of PTAs.

  24. Naturalistic assessment of reaction time variability in older adults at risk for Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Journal of the International Neuropsychological Society : JINS 2024-01-29 Cognitive tests and assessment

    Attentional fluctuations over 20-40 seconds assessed in daily life, are sensitive to clinical status and genetic risk for AD.

  25. Validation, Deployment, and Real-World Implementation of a Modular Toolbox for Alzheimer's Disease Detection and Dementia Risk Reduction: The AD-RIDDLE Project

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. The journal of prevention of Alzheimer's disease 2024-01-01 Cognitive tests and assessment

    The Real-World Implementation, Deployment, and Validation of Early Detection Tools and Lifestyle Enhancement (AD-RIDDLE) project, recently launched with the support of the EU Innovative Health Initiative (IHI) public-private partnership and UK Research and Innovation (UKRI), aims to develop, test, and deploy a modular toolbox platform that can reduce existing barriers to the timely detection, and therapeutic approaches in Alzheimer's disease (AD), thus accelerating AD innovation.

From across this topic

10 of the 1,533 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

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