Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
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Families' reports of unpleasant experiences with end-of-life care may inform practice to improve perceived quality of dying of their loved ones.
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Study results highlight a critical need for better prognostic counseling and education for persons and families living with DLB.
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The spectrum of cognitive decline in the elderly ranges from what can be classified as normal cognitive decline with aging to subjective cognitive impairment to mild cognitive impairment (MCI) to dementia.
Why it matters
This review covers the diagnostic criteria, management, and prevention of mild cognitive impairment from various causes. It states that lifestyle changes such as aerobic exercise are an approved way to preserve cognitive ability and slow progression to dementia, but it does not report a cure for Alzheimer's disease.
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The number of people diagnosed with dementia is expected to rise in the coming years.
Why it matters
Using in-home sensors and machine learning, this system recognized agitation and unusual activity patterns in people with dementia with accuracy up to 80%. This is monitoring technology and does not treat, cure or prevent Alzheimer's disease.
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Many older elective orthopedic surgical patients have probable cognitive impairment preoperatively.
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Keeping these concentrations below the tolerance values prevents the development of manifest and subclinical signs of aluminum toxicity.
Why it matters
This review discusses documented harmful effects of aluminum on health and the threshold values associated with them. It does not establish that aluminum causes Alzheimer's disease, and it calls for large-scale studies on aluminum-containing antiperspirants and breast cancer risk.
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Our multidimensional intervention in long-term care facilities for patients with terminal dementia resulted in improved quality of care and quality of dying when compared to usual care.
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Cerebrovascular and cardiovascular diseases cause vascular brain injury that can lead to vascular cognitive impairment (VCI).
Why it matters
This review describes vascular cognitive impairment as the second most common neuropathology of dementia and mild cognitive impairment, often occurring alongside Alzheimer's disease. It notes that secondary prevention of further vascular brain injury may improve outcomes, but it does not show a cure or proven prevention for Alzheimer's disease.
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47/100
The method presented in this paper can be used to separate stable MCI patients from those who are at early stages of AD dementia with high accuracy.
Why it matters
This study used hippocampal volumetric integrity and a Random Forest classifier to distinguish progressive from stable mild cognitive impairment with 82.3% accuracy, higher in women. It is a prediction method and does not report any treatment, cure, or prevention for Alzheimer's disease.
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Research indicates that stress is linked to cognitive dysfunction.
Why it matters
In this group of older African Americans without dementia, higher perceived stress at the start was linked to faster decline in global cognition, episodic memory and visuospatial ability over up to 9 years. This identifies stress as a possible factor in cognitive decline but does not test any treatment or prevention.
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47/100
It has been proved that the proposed system is suitable to support clinicians to reliably drive and evaluate clinical interventions toward quality of life improvement of people with cognitive impairment.
Why it matters
In four homes of people with cognitive impairment, a smart home monitoring system with tailored interventions was associated with improvement in neuropsychological assessment for all participants. This is a very small study of monitoring and support, not a treatment, cure or prevention of Alzheimer's disease.
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In interviews PWD were able to indicate their treatment preferences across all three scenarios.
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Data synthesis Eszopiclone, zolpidem, and suvorexant improved short-term global and sleep outcomes compared with placebo, although absolute effect sizes were small (low- to moderate-strength evidence).
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There is considerable ambiguity about initiating ACP in dementia at diagnosis among physicians practicing in two different European health care systems and caring for different patient populations.
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It has been suggested that there are several societal and cultural demands on women to adopt the role of a family-caregiver.
Why it matters
This review of family caregivers of people with mental illnesses found that women tend to spend more time providing care and do more personal-care tasks than men. It concerns caregiving roles, not the treatment, cure or prevention of Alzheimer's disease.
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Contextual factors regarding the care home environment may be obdurate and tend to negatively impact on the quality of end of life dementia care.
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Pre-placement surveys identified good dementia knowledge, but poor attitudes towards aged care and older adults.
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Alterations in learning processes and the neural circuitry that supports fear conditioning and extinction represent mechanisms through which trauma exposure might influence risk for psychopathology.
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Alzheimer's disease (AD) is a progressive neurodegenerative disease marked by deficits in episodic memory, working memory (WM), and executive function.
Why it matters
This review tracks decline in working memory and executive function across normal aging, mild cognitive impairment and Alzheimer's disease and suggests cognitive therapies during mild cognitive impairment could reduce the likelihood of progression. It reports no tested treatment, cure or prevention.
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47/100
We quantitated risk of progression to dementia in elderly persons without dementia from 2 population-based studies, the Framingham Heart Study (FHS) and Mayo Clinic Study of Aging (MCSA), aged 70 to 89 years at enrollment.
Why it matters
This study quantified the risk of progressing to dementia among elderly people without dementia based on cognitive test performance. It is about risk prediction and does not report a treatment, cure, or prevention for Alzheimer's disease.
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This benefit is being offered at no cost to eligible Medicare recipients; however, recent reports suggest that few persons are taking advantage of it (1–3) and who is using it is unclear.
Why it matters
This study examined who uses Medicare's Annual Wellness Visit. It provides no information about treating, curing, or preventing Alzheimer's disease.
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Previous studies have indicated a prevalence of dementia in older admissions of ∼42% in a single London teaching hospital, and 21% in four Queensland hospitals.
Why it matters
Among 598 patients aged 70 or over admitted to six hospitals in Cork, Ireland, 25% had dementia (29% in public hospitals), and the authors report that most of it had not been diagnosed before. Dementia was more common in acute medical admissions and rural hospitals, which led the authors to call for cognitive assessment of older people when they arrive at hospital. This is a one-region prevalence snapshot: it does not test screening or any treatment.
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47/100
Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that is increasingly used in research and clinical settings to enhance the effects of cognitive training.
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Use of in-depth data, consensus methods and theoretical understanding of the intervention components produced an evidence-based intervention for further testing in end-of-life care in advanced dementia.
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This review is one of the first to provide an overview of the available literature in relation to strategies used to improve the organisation of palliative care.
From across this topic
10 of the 7,967 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Neurodegeneration across stages of cognitive decline in Parkinson disease
- How effective is cognitive training as a preventive intervention for cognitive decline in individuals at risk of Alzheimer's disease?
- Midlife vascular risk factor exposure accelerates structural brain aging and cognitive decline
- Dysphagia, dystussia, and aspiration pneumonia in elderly people
- The Montreal cognitive assessment (MoCA) 8.1 version, including the memory index score (MoCA-MIS): Italian norms
- Dementia with Lewy bodies
- Does Medicaid Hcbs Generosity Influence Nursing Home Placement for Dually Eligible Adrd Patients?
- Hypnotics should not be considered for the initial treatment of chronic insomnia. Con
- Effects of Exercise and Intensive Vascular Risk Reduction on Cognitive Function in Older Adults: A Randomized Clinical Trial
- Galantamine treatment of vascular dementia: a randomized trial