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60/100

✓ Peer-reviewed alzhub usefulness score 60 out of 100. Getting a diagnosis

Topic: Risk, prevention and care in population studies

Objectives To compare the trajectory of motor decline, as measured by gait speed and finger-tapping speed, between elderly people who developed mild cognitive impairment (MCI) and those who remained cognitively intact. We also sought to determine the approximate time at which the decline in motor function accelerated in persons who developed MCI. Design Longitudinal cohort study. Participants Participants were 204 healthy seniors (57.8% women) from the Oregon Brain Aging Study evaluated for up to 20 years using annual neurologic, neuropsychological, and motor examinations. Main outcome measures The pattern of motor decline with aging was compared using a mixed-effects model with an interaction term for age and a clinical diagnosis of MCI. The time before diagnosis of MCI, when the change in gait or finger-tapping speed accelerates, was assessed using a mixed-effects model with a change point for men and women, separately and combined, who developed MCI. Results The rates of change, with aging, in gait speed (P Conclusions Motor decline as indexed by gait speed accelerates up to 12 years before MCI. Longitudinal changes in motor function may be useful in the early detection of dementia during preclinical stages, when the utility of disease-modifying therapies would be greatest.

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APA 7th

Buracchio, T., Dodge, H. H., Howieson, D., Wasserman, D., & Kaye, J. (2010). The trajectory of gait speed preceding mild cognitive impairment. Archives of neurology. https://doi.org/10.1001/archneurol.2010.159

Vancouver

Buracchio T, Dodge HH, Howieson D, Wasserman D, Kaye J. The trajectory of gait speed preceding mild cognitive impairment. Archives of neurology. 2010. doi:10.1001/archneurol.2010.159. PMID: 20697049.

BibTeX

@article{buracchio2010-20697049,
  author  = {Buracchio, T. and Dodge, H. H. and Howieson, D. and Wasserman, D. and Kaye, J.},
  title   = {{The trajectory of gait speed preceding mild cognitive impairment}},
  journal = {Archives of neurology},
  year    = {2010},
  doi     = {10.1001/archneurol.2010.159},
  pmid    = {20697049},
  url     = {https://doi.org/10.1001/archneurol.2010.159}
}

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Key findings

Results The rates of change, with aging, in gait speed (P Conclusions Motor decline as indexed by gait speed accelerates up to 12 years before MCI.

Why it matters

In this cohort, motor decline as indexed by gait speed accelerated up to 12 years before mild cognitive impairment. Longitudinal changes in motor function may be useful in the early detection of dementia during preclinical stages, when the utility of disease-modifying therapies would be greatest.

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Study details

Study designcohort study
Effect size57.8%
Evidence strengthModerate

How this study scored 60/100

Published in a peer-reviewed journal, and it is a cohort study following people over time. Scored zero for sample size, studied in people and randomized / blinded because the record does not state it.

Component	Points	Why
Journal tier	7 / 10	Tier 3 — peer-reviewed journal (Archives of neurology)
Journal's citation record	3 / 4	Archives of Neurology: journal h-index 353 (OpenAlex, 2026-10-29)
Study design	7 / 12	A cohort study following people over time
Strength of evidence	3 / 5	Rated “moderate” in our summary
Peer-review validation	10 / 10	Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent	1 / 5	2010 — within 20 year(s) of the newest study here
Sample size	0 / 4	Participant count not stated — scores zero (not stated in the record — scored 0)
Effect reported	2 / 3	Effect reported as a number, without an interval or test
Studied in people	0 / 3	Not stated whether this was studied in people — scores zero (not stated in the record — scored 0)
Randomized / blinded	0 / 2	No randomization or blinding stated — scores zero (not stated in the record — scored 0)
Times cited	6 / 7	Cited 565 times (OpenAlex, 2026-10-10)
Citations per year	4 / 5	31.4 citations a year over 18 year(s) since 2010
Impact for its field and year	4 / 6	Cited 8.2× the average for papers of its field and year (OpenAlex FWCI)
Cited by studies here	3 / 6	Cited by 20 other studies in this library
Still being cited	3 / 4	Cited 116 times in 2024–2026 (2026 still in progress; OpenAlex)
Senior author's track record	4 / 4	Last-listed author Jeffrey Alan Kaye: h-index 122 (OpenAlex, whole career)
Institution's track record	1 / 3	Oregon Health & Science University: institution h-index 1,025 (OpenAlex)
Multicenter collaboration	0 / 3	OpenAlex lists 1 institution(s) in 1 country — scores zero (affiliation lists can be incomplete)
Indexed in PubMed	2 / 2	Indexed in PubMed (PMID 20697049)
Free to read	0 / 2	Behind a paywall — scores zero
Total	60 / 100	—

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