Home › Research › Prevention trials
Development and feasibility of a theory-driven multidomain intervention for community-dwelling older adults with mild cognitive impairment: a quasi-experimental pilot study based on the Multi-Theory Model
Ren R, Wei X, Han Y, Wang Q, Sheng S, Liu K, Wei L, Sha L et al.. Research Square, 2026-09-10
Topic: Health services, long-term care and technology
Results Forty participants completed the study (intervention, n = 21; control, n = 19). Recruitment was significantly higher in the intervention group than in the control group (73.3% vs. 40.0%, P = 0.024), and overall adherence was also significantly better (P = 0.007). Compared with the control group, participants receiving the MTM-guided intervention demonstrated significantly greater improvements in global cognitive function, physical performance, instrumental activities of daily living, and social participation (all P < 0.05), together with greater reductions in frailty and depressive symptoms (both P < 0.001). These findings suggest that integrating behaviour change strategies that explicitly target behaviour initiation and maintenance may facilitate the implementation of multidomain interventions in community settings.
Key findings
- Results Forty participants completed the study (intervention, n = 21; control, n = 19).
- Recruitment was significantly higher in the intervention group than in the control group (73.3% vs. 40.0%, P = 0.024), and overall adherence was also significantly better (P = 0.007).
- Compared with the control group, participants receiving the MTM-guided intervention demonstrated significantly greater improvements in global cognitive function, physical performance, instrumental activities of daily living, and social participation (all P < 0.05), together with greater reductions in frailty and depressive symptoms (both P < 0.001).
- These findings suggest that integrating behaviour change strategies that explicitly target behaviour initiation and maintenance may facilitate the implementation of multidomain interventions in community settings.
New to this subject? Start with our plain-English guide: Prevention →
Study details
- Participants20
- Effect size73.3%; 40.0%
- Evidence strengthHigh
How this study scored 16/100
Preprint — not yet peer-reviewed. It scored 37 on the same rubric, but non-peer-reviewed sources are capped at 16, so it shows as 16. Scored zero for study design and randomised / blinded because the record does not state it. We have no data on times cited, citations per year, impact for its field and year, cited by studies here, still being cited, senior author's track record, institution's track record and multi-centre collaboration, so those were left out: it earned 23 of the 62 points we could judge it on, which is 37 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 2 / 10 | Tier 4 — not a peer-reviewed journal (Research Square) |
| Journal's citation record | 0 / 4 | Not a journal article, so the journal's record does not count |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 5 / 5 | Rated “high” in our summary |
| Peer-review validation | 4 / 10 | Preprint — not yet peer-reviewed. Hosted on a preprint server. |
| How recent | 5 / 5 | 2026 — within 1 year(s) of the newest study here |
| Sample size | 1 / 4 | 20 participants |
| Effect reported | 2 / 3 | Effect reported as a number, without an interval or test |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | — / 7 | No citation count (not found in OpenAlex) — left out of this score |
| Citations per year | — / 5 | No citation count or no year — left out of this score |
| Impact for its field and year | — / 6 | No field-weighted citation impact (OpenAlex has none yet) — left out of this score |
| Cited by studies here | — / 6 | Not yet checked against this library's citation graph — left out of this score |
| Still being cited | — / 4 | No yearly citation counts — left out of this score |
| Senior author's track record | — / 4 | Senior author's record not available — left out of this score |
| Institution's track record | — / 3 | No institution listed in OpenAlex — left out of this score |
| Multi-centre collaboration | — / 3 | Institutions not listed — left out of this score |
| Indexed in PubMed | 1 / 2 | Not in PubMed, but has a DOI |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Points | 23 / 62 | Scored on 12 of 20 parts. We have no data for the rest, so they are left out: 23 of the 62 points we could judge it on is 37 out of 100. |
| Total | 37 / 100 | Capped to 16 because this is not a peer-reviewed article. |
What each of these 20 components measures, and what this score is not →
Read the original
Free copy unknown: no free-copy check has an answer for this record yet. That does not mean it is paywalled.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.
APA 7th
Ren, R., Wei, X., Han, Y., Wang, Q., Sheng, S., Liu, K., et al. (2026). Development and feasibility of a theory-driven multidomain intervention for community-dwelling older adults with mild cognitive impairment: a quasi-experimental pilot study based on the Multi-Theory Model. Research Square. https://doi.org/10.21203/rs.3.rs-10443778/v1
Vancouver
Ren R, Wei X, Han Y, Wang Q, Sheng S, Liu K, et al. Development and feasibility of a theory-driven multidomain intervention for community-dwelling older adults with mild cognitive impairment: a quasi-experimental pilot study based on the Multi-Theory Model. Research Square. 2026. doi:10.21203/rs.3.rs-10443778/v1.
BibTeX
@article{ren2026-c2135294,
author = {Ren, R. and Wei, X. and Han, Y. and Wang, Q. and Sheng, S. and Liu, K. and Wei, L. and Sha, L. and others},
title = {{Development and feasibility of a theory-driven multidomain intervention for community-dwelling older adults with mild cognitive impairment: a quasi-experimental pilot study based on the Multi-Theory Model}},
journal = {Research Square},
year = {2026},
doi = {10.21203/rs.3.rs-10443778/v1},
url = {https://doi.org/10.21203/rs.3.rs-10443778/v1}
}
Related studies in Prevention trials
Also tagged “exercise-training”
125 studies in the library carry the topic tag “exercise-training”; these are this study's neighbours in a fixed, alphabetical-by-hash tour of them, not the closest in content. All 125 tagged studies.