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75/100

✓ Peer-reviewed alzhub usefulness score 75 out of 100. Getting a diagnosis

Topic: Risk, prevention and care in population studies

The Mini-Mental State Examination (MMSE) is the best-known and the most often used short screening tool for providing an overall measure of cognitive impairment in clinical, research and community settings. No language or date restrictions were applied to the electronic searches and methodological filters were not used as a method to restrict the search overall so as to maximize sensitivity. Selection criteria We considered longitudinal studies in which results of the MMSE administered to MCI participants at baseline were obtained and the reference standard was obtained by follow-up over time. Main results In this review, we included 11 heterogeneous studies with a total number of 1569 MCI patients followed for conversion to dementia.

Key findings

The Mini-Mental State Examination (MMSE) is the best-known and the most often used short screening tool for providing an overall measure of cognitive impairment in clinical, research and community settings.
No language or date restrictions were applied to the electronic searches and methodological filters were not used as a method to restrict the search overall so as to maximize sensitivity.
Selection criteria We considered longitudinal studies in which results of the MMSE administered to MCI participants at baseline were obtained and the reference standard was obtained by follow-up over time.
Main results In this review, we included 11 heterogeneous studies with a total number of 1569 MCI patients followed for conversion to dementia.

Why it matters

This review included 11 studies of 1569 people with mild cognitive impairment to see whether the Mini-Mental State Examination can detect who later develops dementia. It is a review of a screening tool for early detection, not a treatment, cure, or prevention study.

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Study details

Study designlongitudinal study
Effect size6.2%
Evidence strengthModerate

How this study scored 75/100

Published in a leading specialty journal, and it is a meta-analysis pooling many studies. Scored zero for sample size and studied in people because the record does not state it.

Component	Points	Why
Journal tier	9 / 10	Tier 2 — leading specialty journal (The Cochrane database of systematic reviews)
Journal's citation record	3 / 4	Cochrane Database of Systematic Reviews: journal h-index 468 (OpenAlex, 2026-10-29)
Study design	12 / 12	A meta-analysis pooling many studies (from PubMed type “Meta-Analysis”)
Strength of evidence	3 / 5	Rated “moderate” in our summary
Peer-review validation	10 / 10	Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent	3 / 5	2021 — within 6 year(s) of the newest study here
Sample size	0 / 4	Participant count not stated — scores zero (not stated in the record — scored 0)
Effect reported	2 / 3	Effect reported as a number, without an interval or test
Studied in people	0 / 3	Not stated whether this was studied in people — scores zero (not stated in the record — scored 0)
Randomised / blinded	0 / 2	A review of other studies — randomisation is not credited here
Times cited	6 / 7	Cited 462 times (OpenAlex, 2026-10-10)
Citations per year	5 / 5	66.0 citations a year over 7 year(s) since 2021
Impact for its field and year	6 / 6	Cited 41.6× the average for papers of its field and year (OpenAlex FWCI)
Cited by studies here	3 / 6	Cited by 10 other studies in this library
Still being cited	4 / 4	Cited 337 times in 2024–2026 (2026 still in progress; OpenAlex)
Senior author's track record	2 / 4	Last-listed author Sarah J. Cullum: h-index 25 (OpenAlex, whole career)
Institution's track record	2 / 3	University of Cambridge: institution h-index 1,973 (OpenAlex)
Multi-centre collaboration	3 / 3	OpenAlex lists 14 institution(s) in 5 countries
Indexed in PubMed	2 / 2	Indexed in PubMed (PMID 34313331)
Free to read	0 / 2	Behind a paywall — scores zero
Total	75 / 100	—

What each of these 20 components measures, and what this score is not →

Read the original

Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).

Cite this study APA, Vancouver, BibTeX · download .bib or .ris

Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.

APA 7th

Arevalo-Rodriguez, I., Smailagic, N., Roqué-Figuls, M., Ciapponi, A., Sanchez-Perez, E., Giannakou, A., et al. (2021). Mini-Mental State Examination (MMSE) for the early detection of dementia in people with mild cognitive impairment (MCI). The Cochrane database of systematic reviews. https://doi.org/10.1002/14651858.cd010783.pub3

Vancouver

Arevalo-Rodriguez I, Smailagic N, Roqué-Figuls M, Ciapponi A, Sanchez-Perez E, Giannakou A, et al. Mini-Mental State Examination (MMSE) for the early detection of dementia in people with mild cognitive impairment (MCI). The Cochrane database of systematic reviews. 2021. doi:10.1002/14651858.cd010783.pub3. PMID: 34313331.

BibTeX

@article{arevalorodriguez2021-34313331,
  author  = {Arevalo-Rodriguez, I. and Smailagic, N. and Roqué-Figuls, M. and Ciapponi, A. and Sanchez-Perez, E. and Giannakou, A. and Pedraza, O. L. and Bonfill Cosp, X. and others},
  title   = {{Mini-Mental State Examination (MMSE) for the early detection of dementia in people with mild cognitive impairment (MCI)}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2021},
  doi     = {10.1002/14651858.cd010783.pub3},
  pmid    = {34313331},
  url     = {https://doi.org/10.1002/14651858.cd010783.pub3}
}

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