Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
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Clinicians are encouraged to consider patients' gut health when evaluating and treating psychiatric conditions, such as anxiety and depression.
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41/100
Insulin deficiency or resistance can promote dementia and hallmarks of Alzheimer's disease (AD).
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Alzheimer's disease (AD) is the most common form of dementia and the fifth leading cause of death among the elderly.
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Obesity is a global health problem with a broad set of comorbidities, such as malnutrition, metabolic syndrome, diabetes, systemic hypertension, heart failure, and kidney failure.
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Many recent studies have shown that the gut microbiome plays important roles in human physiology and pathology.
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Metabolic syndrome (MS) is a set of cardio-metabolic risk factors that includes central obesity, hyperglycemia, hypertension, and dyslipidemias.
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The average life expectancy of the world population has increased remarkably in the past 150 years and it is still increasing.
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Alzheimer's disease (AD) is one of the most frequently diagnosed neurodegenerative disorders worldwide and poses a major challenge for both affected individuals and their caregivers.
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41/100
Alzheimer's disease (AD), a progressive neurodegenerative disorder characterized by memory loss and cognitive decline, is a major cause of death and disability among the older population.
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No significant cytotoxicity was observed at ART concentrations up to 40 μM. ART could significantly increase the viability of SH-SY5Y cells treated with MPP+ and reduce oxidative stress damage and apoptosis.
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41/100
Alterations in brain cholesterol homeostasis in midlife are correlated with a higher risk of developing Alzheimer's disease (AD).
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41/100
Increasing evidence suggests that gut dysbiosis plays vital roles in a variety of gut-brain disorders, such as Alzheimer's disease (AD).
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Chronic cerebral hypoperfusion (CCH) may lead to the cognitive dysfunction, but the underlying mechanisms are unclear.
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Recent investigations have increased the interest on the connection between the microorganisms inhabiting the gut (gut microbiota) and human health.
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The Mediterranean diet (MD) is becoming a milestone for the prevention of chronic diseases, such as cardiovascular diseases (CVDs), Alzheimer's and Parkinson's disease.
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The microbiota-gut-brain axis is a bidirectional signaling mechanism between the gastrointestinal tract and the central nervous system.
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The human digestive system is embedded with trillions of microbes of various species and genera.
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This cycle is challenging to study, as its bidirectional nature renders cause difficult to disentangle from effect.
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Mitochondrial unfolded protein response (UPRmt) is a mitochondria stress response, which the transcriptional activation programs of mitochondrial chaperone proteins and proteases are initiated to maintain proteostasis in mitochondria.
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41/100
The human microbiota has a fundamental role in host physiology and pathology.
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41/100
Gut microbiota represents a complex physiological ecosystem that influences the host health.
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The glymphatic system is a "pseudo-lymphatic" perivascular network distributed throughout the brain, responsible for replenishing as well as cleansing the brain.
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Brain-derived neurotrophic factor (BDNF) is one of the most distributed and extensively studied neurotrophins in the mammalian brain.
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These data for the first time provide evidence of potential causal links between gut microbiome and AD, MDD, and SCZ.
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41/100
Understanding how gut flora influences gut-brain communications has been the subject of significant research over the past decade.
From across this topic
9 of the 1,048 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 9. The same 9 appear here every time.
- Therapeutic potential of the original incretin hormone glucose-dependent insulinotropic polypeptide: diabetes, obesity, osteoporosis and Alzheimer's disease?
- Serum IgG antibody levels to periodontal microbiota are associated with incident Alzheimer disease
- Omega-3 fatty acids, pro-inflammatory signaling and neuroprotection
- Protein carbonylation in human diseases
- The 25-Year Evolution of Lithium as a Disease-Modifying Agent in Dementia: A Narrative Review
- Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing
- Cyclooxygenases 1 and 2
- Metabolic, inflammatory, and microvascular determinants of white matter disease and cognitive decline
- Elevated circulating amyloid concentrations in obesity and diabetes promote vascular dysfunction