Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
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Probiotic supplements were shown to improve cognitive function in Alzheimer's disease (AD) patients.
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70/100
The results showed that intestinal expression of GLP-1 1 could reduce the intestinal pathogenic genus such as Enterobacteriaceae and was obviously associated with a greater number of beneficial genera such as Lactobacillus and Akkermansia.
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Emerging evidence of brain injury on risk of neurodegenerative diseases such as Alzheimer's disease (AD) and chronic traumatic encephalopathy (CTE) have resulted in interest in therapeutic potential of omega-3 fatty acids (n-3FA).
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70/100
These data suggest that resveratrol decreases CSF MMP9, modulates neuro-inflammation, and induces adaptive immunity.
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The grey matter of the brain contains high levels of the essential nutrient DHA.
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We concluded that liraglutide improves cognitive decline in patients with type 2 diabetes mellitus.
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69/100
This population-based cohort study demonstrates significant association between IBD and subsequent development of dementia.
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Cognitive frailty, defined as the coexistence of mild cognitive impairment symptoms and physical frailty phenotype in older persons, is increasingly considered the main geriatric condition predisposing to dementia.
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Epidemiological evidence reveals that patients with type 2 diabetes mellitus (T2DM) have an increased risk of neurodegenerative diseases (NDs), including dementia and Parkinson's disease (PD).
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69/100
Serum IgG levels to common periodontal microbiota are associated with risk for developing incident AD.
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The prevalence of dementia worldwide is growing at an alarming rate.
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A nutritional approach could be a promising strategy to prevent or slow the progression of neurodegenerative diseases such as Parkinson's and Alzheimer's disease, since there is no effective therapy for these diseases so far.
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The positive finding of lower EV Aβ42 supports emerging evidence that plasma neuronal EVs provide an effective platform for demonstrating biomarker responses in clinical trials in AD.
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66/100
Emerging evidence suggests a potential role of gut dysbiosis in neurodegenerative disorders and, in particular, Alzheimer's disease (AD) pathology and cognitive decline.
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We analyzed 128 participants (women: 59%, mean age: 74 years).
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Liraglutide might slow down memory function decline in diabetic patients in early, and possibly preclinical stages of the disease.
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Recent literature shows that GLP-1 and its agonists, DPP-4 inhibitors and combined GLP-1/GIP molecules are effective in partially or fully reversing the effects of neurotoxic compounds, neurovascular complications of diabetes, neuropathological changes related with Alzheimer's disease, Parkinson's disease or vascular occlusion.
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Insulin resistance (IR) is a metabolic state preceding development of type 2 diabetes (DM2), cardiovascular disease, and neurodegenerative disorders, including Alzheimer's Disease (AD).
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RECENT FINDINGS: Based on available epidemiological studies, two meta-analyses published in 2013 have underlined a protective effect of a greater MeDi adherence on cognitive health, including a reduced risk of Alzheimer's disease and cognitive impairment.
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DeFronzo Metrics Cited ByDiscovery of α-Glucosidase Inhibitors from Marine Microorganisms: Optimization of Culture Conditions and Medium CompositionBurdock fructooligosaccharide as an α-glucosidase inhibitor and its antidiabetic effect on high-fat diet and streptozotocin-induced diabetic miceThe antioxidant and antidiabetic potentials of polyphenolic-rich extracts of Cyperus rotundus (Linn.)From Pharmacogenetics to Gene Expression: Implications for Precision Medicine in DiabetesA narrative review of current trends in liraglutide: insights into the unmet needs in management of type 2 diabetes and obesitySynthesis, antidiabetic, antioxidant and anti-inflammatory activities of novel hydroxytriazenes based on sulpha drugsRNA-Seq Analysis of the Liver Transcriptome Reveals the Networks Regulating Treatment of Sitagliptin Phosphate plus Fuzhujiangtang Granule in the Zucker Diabetic Fatty RatsEverestmab, a novel long-acting GLP-1/anti GLP-1R nanobody fusion protein, exerts potent anti-diabetic effectsSPION‐Decorated Exosome Delivered BAY55‐9837 Targeting the Pancreas through Magnetism to Improve the Blood GLC ResponseA novel self-sufficient biocatalyst based on transaminase and pyridoxal 5′-phosphate covalent co-immobilization and its application in continuous biosynthesis of sitagliptinShared Pathological Mechanisms Between Diabetes Mellitus and Neurodegenerative DiseasesEffects of Lifestyle Modification and Anti-diabetic Medicine on Prediabetes Progress: A Systematic Review and Meta-AnalysisGlibenclamide Reduces Primary Human Monocyte Functions Against Tuberculosis Infection by Enhancing M2 PolarizationNaringin enhances reverse cholesterol transport in high fat/low streptozocin induced diabetic ratsA novel strategy to prepare the precursor peptide of liraglutideImpact of metformin on patients with advanced head and neck cancer undergoing concurrent chemoradiotherapyEffects of Different Doses of Metformin on Serum Fatty Acid Composition in Type 2 Diabetic RatsInsulin resistance and cognitive performance in type 2 diabetes — The Maastricht studyDesign and synthesis of novel thiazolidine-2,4-diones as hypoglycemic agentsMetformin in Amnestic Mild Cognitive Impairment: Results of a Pilot Randomized Placebo Controlled Clinical TrialMetformin and lifestyle modification in polycystic ovary syndrome: systematic review and meta-analysisGlibenclamide reduces pro-inflammatory cytokine production by neutrophils of diabetes patients in response to bacterial infectionNa + /H
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Alzheimer's disease (AD) is a progressive, degenerative disorder of the central nervous system.
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The observed metabolic alterations were associated with core pathological processes of AD to investigate their relation with amyloid pathology and tau-related neurodegeneration.
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Coffee is the leading worldwide beverage after water and its trade exceeds US $10 billion worldwide.
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Previous studies have suggested an acutely improving effect of insulin on memory function.
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136 adults with T1D (n=90, age 52 years, 58% female, average HbA1c 7.7%) and without T1D (n=46, age 53 years, 57% female, average HbA1c 5.4%) were included.