Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
-
Reactive oxygen species (ROS) are metabolic byproducts that are necessary for physiological function but can be toxic at high levels.
-
Luteolin is a flavonoid in a variety of fruits, vegetables, and herbs, which has shown anti-inflammatory, antioxidant, and anti-cancer neuroprotective activities.
-
An excess of saturated fatty acids and simple sugars in the diet is a known environmental risk factor of Alzheimer's disease (AD) but the holistic view of the interacting processes through which such diet may contribute to AD pathogenesis is missing.
-
40/100
Type 2 diabetes mellitus and the associated desensitisation of insulin signalling has been identified as a risk factor for progressive neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease and others.
-
The glucagon-like peptide-1 (GLP-1) was shown to have neuroprotective effects in Alzheimer's disease (AD).
-
There has been a steep increase in allergic and autoimmune diseases, reaching epidemic proportions and now affecting more than one billion people worldwide.
-
Alzheimer's disease (AD) is a progressive neurodegenerative disease, also regarded as "type 3 diabetes" for the last few years because of the brain insulin resistance (IR) and dysregulation of insulin signaling in the brain, which can further promote pathological progression of AD.
-
While the elderly segment of the population continues growing in importance, neurodegenerative diseases increase exponentially.
-
The enteric nervous system (ENS) is the largest division of the peripheral nervous system and closely resembles components and functions of the central nervous system.
-
40/100
Cholesterol is an indispensable component of the cell membrane and plays vital roles in critical physiological processes.
-
The gut microbiota is a complex ecosystem that comprises of more than 100 trillion symbiotic microbial cells.
-
40/100
Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of antidiabetic drugs that improve the glycaemia via several molecular pathways.
-
Hyperglycemia in diabetes mellitus (DM) patients is a causative factor for amyloidogenesis and induces neuropathological changes, such as impaired neuronal integrity, neurodegeneration, and cognitive impairment.
-
40/100
Black pepper is an autoicous and decorous vine cultivated and harvested in tropical regions of Sri Lanka and India.
-
Vildagliptin (Vilda), a dipeptidyl peptidase-4 (DPP-4) inhibitor, has been highlighted as a promising therapeutic agent for neurodegenerative diseases as Alzheimer's and Parkinson's diseases.
-
High fat diet-induced obesity is associated with insulin resistance (IR) and other chronic, diet related illnesses, including dementia.
-
The human microbiome consists of ~3.8 × 10 13 symbiotic microorganisms that form a highly complex and dynamic ecosystem: the gastrointestinal (GI) tract constitutes the largest repository of the human microbiome by far, and its impact on human neurological health and disease is becoming increasingly appreciated.
-
Age-related hearing loss (ARHL) -presbycusis - is the most prevalent neurodegenerative disease and number one communication disorder of our aged population; and affects hundreds of millions of people worldwide.
-
The present review is focused on juvenile neuronal ceroid lipofuscinosis (JNCL; Batten disease) due to a mutation in CLN3 .
-
Severe amyloidosis and plaque-localized neuro-inflammation are key pathological features of Alzheimer's disease (AD).
-
One of the major histopathological hallmarks of Alzheimer's disease (AD) is cerebral deposits of extracellular β-amyloid peptides.
-
Antioxidants are substances that may protect cells from the damage caused by unstable molecules such as free radicals.
-
Neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD) enforce an overwhelming social and economic burden on society.
-
Alzheimer's disease (AD) is the most common cause of disability in individuals aged >65 years worldwide.
-
Chronic brain ischemia is a prominent risk factor for neurological dysfunction and progression for dementias, including Alzheimer's disease (AD).
From across this topic
10 of the 1,048 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Role of Phenolic Compounds in Human Disease: Current Knowledge and Future Prospects
- Inflammation in obesity, diabetes, and related disorders
- Twenty years of research on cytokine-induced sickness behavior
- RETRACTED: Liraglutide Has Anti-Inflammatory and Anti-Amyloid Properties in Streptozotocin-Induced and 5xFAD Mouse Models of Alzheimer's Disease
- Protective Effects of Incretin Against Age-Related Diseases
- Systemic and central nervous system metabolic alterations in Alzheimer's disease
- Intranasal insulin improves memory in humans
- Gut-brain relationship in dementia and Alzheimer's disease: Impact on stress and immunity
- Microbiota-Gut-Brain Axis Dysregulation in Alzheimer's Disease: Multi-Pathway Effects and Therapeutic Potential
- Glutathione, oxidative stress and neurodegeneration