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controlled
1,138 studies tagged controlled, dated 1986-09-01 to 2026-09-23. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Alcohol use disorder accelerates age-related cognitive decline 2026-09-23
- A longitudinal study of age-related traits and cognitive function: The Collaborative Amish Aging and Memory Project (CAAMP) 2026-09-20
- Associations of menopause hormone therapy with late-life cognition and brain health vary by formulation and APOEε4 presence 2026-09-20
Studies
1,138 studies carry this tag.
Date range
1986 to 2026
Top journals
- Alzheimer s & Dementia 42
- Neurology 41
- Journal of the American Geriatrics Society 36
- Journal of Alzheimer's disease : JAD 33
- Nutrients 23
437 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Through systematic instruction and retraining visual and sustained attention, the patient was able to engage meaningfully with a high-tech device to increase functional personal choice when supported by a partner.
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Cognition-oriented treatments (COTs) are a group of non-pharmacological treatments aimed at maintaining or improving cognitive functioning.
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ADI was positively associated with blood pressure and cardiometabolic index (CMI), and negatively associated with global and Preclinical Alzheimer's Cognitive Composite (PACC5) scores, in cognitively unimpaired (CU) individuals.
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Postoperative cognitive dysfunction (POCD) is a common and serious postoperative complication in elderly patients, affecting cognitive function and quality of life.
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Greater MIND diet adherence was associated with decreased risk of cognitive impairment in female participants but not male participants, with no difference between Black participants and White participants.
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The effects were not statistically significant on other outcomes.
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Extensive evidence shows the beneficial effect of adhering to a regular physical activity (PA) pattern on brain health.
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A brain transcriptomic profile for healthy diets revealed novel genes potentially associated with cognitive health.
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74/100
This meta-analysis pooled data from 24 observational studies covering over half a million older adults to ask whether cataract surgery is associated with lower long-term cognitive decline compared with leaving cataracts untreated.
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Of 4413 individuals (mean [SD] age, 71.27 [4.66] years, 2617 women [59.3%]), mean Aβ-PET was elevated in individuals with history of memory impairment in both parents (n = 455; mean [SD] standardized uptake value ratio [SUVR] = 1.12 [0.19]; Wilcoxon P = 1.1 × 10-5) and in those with only maternal history (n = 1772; mean [SD] SUVR = 1.10 [0.19]; Wilcoxon P = 2.70 × 10-5) compared with those with only paternal history (n = 632; mean [SD] SUVR = 1.08 [0.18]; Wilcoxon P = 1.1 × 10-5) or no family history (n = 1554; mean [SD] SUVR = 1.08 [0.19]; Wilcoxon P = 1.1 × 10-5).
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The AgeWell.de intervention reduced dementia risk.
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Neighborhood disadvantage is associated with worse health and cognitive outcomes.
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MAF supplementation improved cognitive function, especially after 6 months, in elderly people undergoing rehabilitation.
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's < 0.05). The findings suggest that neighborhood-level social deprivation might influence memory and motor status, primarily through its impact on motor brain health.
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Maintaining driving independence is important for older adults.
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Within 17 months, participant recruitment has been successfully completed (N = 1210; mean age: 67.7 years (SD: 4.6); 64% female).
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The cognitive impairment cohort (n = 14,175) included participants without evidence of impairment at baseline who underwent follow-up testing.
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With dementia incidence projected to escalate significantly within the next 25 years, the United Nations declared 2021-2030 the Decade of Healthy Ageing, emphasising cognition as a crucial element.
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The combinations of pathologies of Alzheimer's disease and related dementias associated with cognitive and motor decline and their onsets of associations varied; only tau tangles, Parkinson's disease pathology, and macroinfarcts were associated with decline of all three phenotypes.
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Of 586 included decedents, 415 (70.8%) were female, 171 (29.2%) were male, and the mean (SD) age at death was 90.9 (6.0) years.
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Higher levels of physical activity are known to benefit aspects of brain health across the lifespan.
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People with MCI are at increased risk of developing AD.
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Higher ADI was significantly associated with lower MMSE score.
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80/100
In this meta-analysis of the association of physical activity with cognitive decline, physical activity was associated with better late-life cognition, but the association was weak.
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The Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) diet seems a promising approach to preserve brain function during aging.
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MET-FINGER aims to test a FINGER 2.0 multimodal intervention, combining an updated FINGER multidomain lifestyle intervention with metformin, where appropriate, in an APOE ε4-enriched population of older adults (60-79 years) at increased risk of dementia.
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Many epidemiological studies have shown the beneficial effects of a largely plant-based diet, and the strong association between the consumption of a Mediterranean-type diet with healthy aging including a lower risk of cognitive decline.
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Summary statistics were obtained for sociodemographic and chronic diseases by using cross-tabulation analysis and comparing the county respondents with proportion tests.
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The 172 total participants had a mean (SD) age of 75.7 (4.8) years, and 108 (62.8%) were women.
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This is the first study to investigate urine biomarker through exercise intervention.
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Both participant and study partner CFI increased over the duration of the study indicating worsening cognitive functioning.
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MAs were younger, more likely to be female, less educated, had higher ADI scores, performed worse on trails B (all p < 0.05), and had lower prevalence of APOE4 + when compared to NHWs (p < 0.0001).
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Our primary outcome was self‐reported history of cognitive screening (never versus ever had screening).
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This study reveals significant differences in driving patterns between cognitively normal older adults and those with cognitive impairment.
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Given that Black Americans have been found to have a higher prevalence of sleep disturbances compared to white Americans, our findings could add to inform future health interventions and policy recommendations that can address modifiable sources of poorer brain health in Black men.
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Participants racialized as Black who lived in places with higher levels of area‐level structural socioeconomic racism experienced lower levels of cognition at baseline and at varying time points in the six‐year period—compared to those in places with lower structural socioeconomic racism.
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Our results suggest that the relationship between greater neighborhood disadvantage and poorer cognitive function are very subtle and may only be present for some, but not all, cognitive domains.
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Ten‐year Black‐White disparities in prison population are associated with cognitive decline among people racialized as Black starting one year later.
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Approximately half of the sample were persistently food secure, 17% became food secure, 14% became FI, and 15% experienced persistent FI.
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The study population of 99,774 individuals had a mean age of 71.0 years and was 49.1% female, 73.9% White, and 17.8% Black, with 62.0% living in an urban setting.
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Physical exercise and cognitive and social enrichment activities can enhance cognitive function in patients with chronic stroke, but their cost-effectiveness compared with a balance and tone program is uncertain.
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These programs are considered beneficial nonpharmacological cognitive training interventions for middle-aged women at high risk of cognitive impairment.
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Few nutritional interventions were found to convincingly improve cognition of individuals with MCI.
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Neighborhood disadvantage was selectively associated with cognitive measures heavily influenced by executive function, namely using an efficient word generation strategy, and incorporating feedback to guide problem-solving.
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The intervention did not improve global cognitive performance.
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We are conducting a single-blinded, National Institutes of Health stage-2, randomized clinical trial to establish the efficacy of AB versus a time-matched and dose-matched education control (Health Enhancement Program [HEP]) in improving self-reported and objective outcomes of physical, cognitive, and emotional functions in 260 participants.
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The prevalence of cognitive impairment, MCI, and dementia among participants aged 60 years and older were 21.48% (95% CI, 19.90-23.10), 15.70% (95% CI, 14.30-17.10), and 5.77 (95% CI, 4.90-6.70), respectively.
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We will use results from this study to develop the first live video telehealth dyadic resiliency intervention focused on the prevention of chronic emotional distress in couples shortly after ADRD diagnoses.
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This randomized trial gave hearing aids plus counseling, or only general health education, to 977 older adults with untreated hearing loss, then tracked cognition for three years.
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This review suggests the advantage of combined interventions over exercise with comparable effects when compared with cognitive interventions in the population with mild cognitive impairment and dementia.
From across this tag
10 of the 1,130 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Effects of nutrients (in food) on the structure and function of the nervous system: update on dietary requirements for brain. Part 2 : macronutrients
- Evidence of neurodegeneration in obstructive sleep apnea: Relationship between obstructive sleep apnea and cognitive dysfunction in the elderly
- Neurocognitive enhancement in older adults: comparison of three cognitive training tasks to test a hypothesis of training transfer in brain connectivity
- Damaging effects of a high-fat diet to the brain and cognition: a review of proposed mechanisms
- n-3 Fatty acids, Mediterranean diet and cognitive function in normal aging: A systematic review
- Adherence to a Mediterranean-type dietary pattern and cognitive decline in a community population
- Links between cognitive impairment in insulin resistance: an explanatory model
- Maintaining older brain functionality: A targeted review
- Left ventricular dysfunction: a clue to cognitive impairment in older patients with heart failure
- Towards Combinatorial Approaches for Preserving Cognitive Fitness in Aging