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controlled
1,138 studies tagged controlled, dated 1986-09-01 to 2026-09-23. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Alcohol use disorder accelerates age-related cognitive decline 2026-09-23
- A longitudinal study of age-related traits and cognitive function: The Collaborative Amish Aging and Memory Project (CAAMP) 2026-09-20
- Associations of menopause hormone therapy with late-life cognition and brain health vary by formulation and APOEε4 presence 2026-09-20
Studies
1,138 studies carry this tag.
Date range
1986 to 2026
Top journals
- Alzheimer s & Dementia 42
- Neurology 41
- Journal of the American Geriatrics Society 36
- Journal of Alzheimer's disease : JAD 33
- Nutrients 23
437 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Among older adults, MeDi adherence was associated with less brain atrophy, with an effect similar to 5 years of aging.
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This trial found no benefit of 24-month multidomain intervention with focus on improvement in lifestyle and vascular risk factors on the incidence of poststroke cognitive decline in comparison with standard stroke care.
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47/100
Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that is increasingly used in research and clinical settings to enhance the effects of cognitive training.
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A number of health and lifestyle factors are thought to contribute to cognitive decline associated with age but cannot be easily modified by the individual patient.
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The influence of mixed dietary patterns on cognitive changes is unknown.
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Our findings suggest that an adapted Mediterranean diet or a wheat-based, diverse diet with similar components may reduce the rate of cognitive decline in later life in the Chinese population.
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Research increasingly suggests that subjective cognitive decline (SCD) in older adults, in the absence of objective cognitive dysfunction or depression, may be a harbinger of non-normative cognitive decline and eventual progression to dementia.
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Increasing research has evidenced that our brain retains a capacity to change in response to experience until late adulthood.
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Even without subjective cognitive complaints, higher risk of cognitive impairment is presented in the prefrail and frail individuals.
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The incidence of dementia and obstructive sleep apnea (OSA) increases with age.
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Physical as well as cognitive training interventions improve specific cognitive functions but effects barely generalize on global cognition.
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Among sedentary older adults, a 24-month moderate-intensity physical activity program compared with a health education program did not result in improvements in global or domain-specific cognitive function.
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Replication of these findings in a dietary intervention trial would be required to verify its relevance to brain health.
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The unprecedented growth in the number of older adults in our society is accompanied by the exponential increase in the number of elderly people who will suffer cognitive decline and dementia in the next decades.
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The study will provide evidence for evaluating and understanding the role of electroacupuncture in the treatment of Alzheimer's disease.
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It is hypothesised that exercise and Mediterranean diet interventions, both individually and in combination, will result in improvements in cognitive performance compared with controls.
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In models adjusting for individual demographic and health characteristics, Hispanic composition had a significant positive association with cognitive function (standardised β=0.136, p<0.05) and moderate evidence of an association with greater cognitive decline (standardised β=-0.014, p=0.09).
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The original validation study for the Montreal Cognitive Assessment (MoCA) suggests a cutoff score of 26; however, this may be too stringent for older adults, particularly for those with less education.
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74/100
Also, we performed analyses including only trials in which an increase in the cardiovascular fitness of participants had been demonstrated.
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There is evidence that physical activity (PA) is of cognitive benefit to the ageing brain, but little is known on the effect in patients with Alzheimer's disease (AD).
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There was a significant interaction (P = 0.024) between B vitamin treatment and plasma combined ω-3 fatty acids (eicosapentaenoic acid and docosahexaenoic acid) on brain atrophy rates.
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Our findings in CPAP+ participants suggest that CPAP treatment of SDB may delay progression of cognitive impairment.
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The present study investigates whether a combined cognitive and physical training may induce changes in the cortical activity as measured via electroencephalogram (EEG) and whether this change may index a deceleration of pathological processes of brain aging.
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Online literature databases and trial registers, previous systematic reviews and leading journals were searched for relevant randomised controlled trials.
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Low daytime SBP was independently associated with a greater progression of cognitive decline in older patients with dementia and MCI among those treated with AHDs.
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TBI patients' brains were estimated to be older than their chronological age.
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Epidemiologic evidence suggests that cognitive and physical activities are associated with better cognition in late life.
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This Finnish randomized controlled trial was the first large study to show that a two-year program combining diet counseling, exercise, cognitive training, and monitoring of heart-health risk factors could help maintain or improve thinking skills in older adults at elevated dementia risk, compared with a control group who received only general health advice.
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Modifiable vascular and lifestyle-related risk factors have been associated with dementia risk in observational studies.
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Hearing loss is associated with poor cognitive performance and incident dementia and may contribute to cognitive decline.
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A prolonged preclinical phase of more than two decades before the onset of dementia suggested that initial brain changes of Alzheimer's disease (AD) and the symptoms of advanced AD may represent a unique continuum.
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Cognitive training, physical activity, and exercise have often been reported to improve cognitive performance in older adults.
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61/100
Although APOE ε4 carriers are at high risk for cognitive decline, our findings suggest possible intervention targets, including the enhancement of cognitive reserve and improvement of other psychosocial and health factors, to promote cognitive resilience among black and white APOE ε4 carriers.
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A higher adherence to the MedDiet might be associated with better cognitive function.
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However, further research is needed with studies using larger sample sizes, standardized measurement outcomes, and longer follow-up periods, to inform evidence-based recommendations.
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Effective communication by nursing home staff is related to a higher quality of life and a decrease in verbal and physical aggression and depression in nursing home residents.
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The incidence of dementia and cardiovascular disease (CVD) increases with age.
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69/100
Personality is associated with cognitive decline in older adults, with effects comparable to established clinical and lifestyle risk factors.
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We found no strong associations with development of cognitive dysfunction for any of the dietary patterns investigated.
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Epidemiologic studies suggest that a Mediterranean diet, an antioxidant-rich cardioprotective dietary pattern, delays cognitive decline, but clinical trial evidence is lacking.
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The HBA-CT program improves cognitive, mood, and sleep functions in older adults 'at risk' of dementia, and therefore offers promise as a secondary prevention strategy.
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This study gives evidence that cognitive training may be effective to prevent cognitive decline and onset of MCI in PD patients.
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Closer adherence to the traditional MD is highly likely to protect against cognitive decline in this elderly Mediterranean population.
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The close relationship between stroke and dementia is an important health issue.
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The intervention effect was found in delayed verbal memory.
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The incidence of obesity in middle age is increasing markedly, and in parallel the prevalence of metabolic disorders including cardiovascular disease and type II diabetes is also rising.
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The overall effect size (Hedges' g, random effects model) for CCT versus control was small and statistically significant, g = 0.22 (95% CI 0.15 to 0.29).
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In the present study we tested the cognitive effects of transcranial direct current stimulation (tDCS) in a case of probable Alzheimer disease (AD).
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It has been estimated that 5.1million Americans suffer from heart failure.
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Mediterranean diet is a term used to describe the traditional eating habits of people in Crete, South Italy and other Mediterranean countries.
From across this tag
10 of the 1,130 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Effect of baseline cognitive function and antihypertensive treatment on cognitive and cardiovascular outcomes: Study on COgnition and Prognosis in the Elderly (SCOPE)
- The role of diet in cognitive decline
- Dietary patterns and cognitive decline in an Australian study of ageing
- Heart Rate Variability and Cognitive Function: A Systematic Review
- Virgin olive oil supplementation and long-term cognition: the PREDIMED-NAVARRA randomized, trial
- Olive oil and cognition: results from the three-city study
- The effect of physical activity on cognitive function in patients with dementia: A meta-analysis of randomized control trials
- Connections between sleep and cognition in older adults
- Eye‐Tracking‐Based Cognitive Assessment Predicts the Risk of Memory Decline: A Community‐Based Cohort Study
- Gait and cognition: a complementary approach to understanding brain function and the risk of falling