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controlled
1,138 studies tagged controlled, dated 1986-09-01 to 2026-09-23. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Alcohol use disorder accelerates age-related cognitive decline 2026-09-23
- A longitudinal study of age-related traits and cognitive function: The Collaborative Amish Aging and Memory Project (CAAMP) 2026-09-20
- Associations of menopause hormone therapy with late-life cognition and brain health vary by formulation and APOEε4 presence 2026-09-20
Studies
1,138 studies carry this tag.
Date range
1986 to 2026
Top journals
- Alzheimer s & Dementia 42
- Neurology 41
- Journal of the American Geriatrics Society 36
- Journal of Alzheimer's disease : JAD 33
- Nutrients 23
437 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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One randomized clinical trial (RCT) (n = 4005) examined the direct effect of screening for cognitive impairment on patient outcomes, including potential harms, finding no significant differences in health-related quality of life at 12 months (effect size, 0.009 [95% CI, -0.063 to 0.080]).
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Hearing loss is a modifiable risk factor for dementia in older adults.
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These results add to the body of evidence on the adverse impact of ambient air pollution on cognitive aging and brain health and provide new insights into the genetic and behavioral factors that may impact individual susceptibility.
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Overall, the psychological intervention and cognitive training may be beneficial to cognitive function and psychological well-being.
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This study founded that low gait speed was significantly associated with dementia in older adults in nursing home.
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58/100
Accounting for educationalfactors, vascular factors, and Aβ burden diminished, but did not eliminate, racial differences in PACC5 performance longitudinally.
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The most prominent results indicated that high total intake of fruits and vegetables, and some of their specific subgroups including berries, citrus, and green leafy vegetables, may promote higher levels of optimism and self-efficacy, as well as reduce the level of psychological distress, ambiguity, and cancer fatalism, and protect against depressive symptoms.
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Cognitive training in MCI may be enhanced by atDCS, but further delineation of the impact of current brain state, as well as temporal characteristics of multi-session atDCS-training application, may be needed to induce longer-lasting effects.
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Greater lifetime stress predicted poorer later-life cognition, and, in a small sample of African Americans, faster declines in a key domain of episodic memory.
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Previously, we found that circadian desynchrony was involved in isoflurane-induced cognitive impairment.
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These results suggest pairing tDCS with cognitive training enhances functional connectivity and working memory performance in older adults, and thus may hold promise as a method for remediating age-related cognitive decline.
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An individual's brainAGE is the difference between chronological age and age predicted from machine-learning models of brain-imaging data.
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This pilot study showed that functional tasks exercise using simulated functional tasks as a means of combined cognitive and exercise program is feasible and beneficial in improving the memory and functional status of older adults with mild cognitive impairment as well as reducing the care-related burdens of their caregivers.
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Prior research suggests that both exergaming and virtual reality (VR)-based training programs could improve executive functions in older adults.
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69/100
The age of the population is shifting toward the elderly range, which may lead to an increased risk of mild cognitive impairment (MCI).
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Older adults with mild dementia demonstrated worse baseline cognitive performance than participants without dementia.
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Postoperative cognitive dysfunction (POCD) is a common disorder following surgery, which seriously threatens the quality of patients' life, especially the older people.
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Hispanics/Latinos are the largest ethnic/racial group in the United States and at high risk for Alzheimer's disease and related dementia (ADRD).
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Functional decline is associated with risk and can be efficiently assessed by participants and study partners (SPs).
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Study objectives We investigated the effectiveness of a lighting intervention tailored to maximally affect the circadian system as a nonpharmacological therapy for treating problems with sleep, mood, and behavior in persons with Alzheimer disease and related dementias (ADRD).
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The aging population is expanding, as is the prevalence of age-related cognitive decline (ARCD).
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As there is currently no cure for dementia, there is an urgent need for preventive strategies.
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CCT was most effective in cognitive rehabilitation, particularly in the subdomain of memory.
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Dietary habits and vascular risk factors promote both Alzheimer's disease and cognitive impairment caused by vascular factors 1-3 .
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In each cohort, achieving just 10-21.4 min/day moderate-to-vigorous PA related to better executive function ( P P = .02).
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Higher adherence to the MedDiet is associated with better cognitive function and lower risk of poor cognition in older UK adults.
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Age-related hearing loss (ARHL) or presbycusis, as the third leading cause of chronic disability in older adults, has been shown to be associated with predisposing cognitive impairment and dementia.
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The mechanisms of action of the dietary components of the Mediterranean diet are reviewed in prevention of cardiovascular disease, stroke, age-associated cognitive decline and Alzheimer disease.
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Use of HAs is associated with delayed diagnosis of AD, dementia, depression, anxiety, and injurious falls among older adults with HL.
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It has been reported that taurine intake in the past may have a positive effect on present cognitive function in the elderly.
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In older adults, hearing loss is independently associated with an increased rate of cognitive decline, and has been identified to be a modifiable risk factor for dementia.
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So far, however, only few such multi-component trials have been launched, but yielding promising results.
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Adjusted for demographic and health behavior as well as health condition risk factors, desktop and cellphone ownership were independently associated with subsequent decreased cognitive decline over the four-year period.
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With no effective treatments for cognitive decline or dementia, improving the evidence base for modifiable risk factors is a research priority.
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The possibilities of computer-based cognitive training (CCT) in postponing the onset of dementia are currently unclear, but promising.
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Both increased sympathetic activity and decreased parasympathetic activity seem to be associated with a worse performance in the cognitive domains considered, in the absence of dementia and severe cardiovascular diseases or other medical and psychiatric diseases.
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As one of few meta-analyses comparing different quantities of physical activity and exercise interventions for AD in details, our study suggests that physical activity and exercise can improve cognition of older adults with AD.
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Change in occupational performance predicted change in depressive symptoms.
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Overall health is significantly impacted by where one lives.
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Moreover, physical activity in the elderly is associated with a decreased risk of mortality, of common chronic illnesses (i.e. cardiovascular disease or osteoarthritis) and of institutionalization as well as with a delay in functional decline.
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The FINGER MRI exploratory sub-study did not show significant differences between the intervention and control groups on changes in regional brain volumes, regional cortical thicknesses, or WML volume after 2 years in at-risk elderly without substantial impairment.
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75/100
There is moderate-to-strong support that PA benefits cognitive functioning during early and late periods of the life span and in certain populations characterized by cognitive deficits.
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Along with rapid global population aging, the age-related cognitive disorders such as mild cognitive impairment (MCI) and dementia have posed a serious threat to public health, health care system, and sustainable economic and societal development of all countries.
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Cognitive training is a popular intervention aimed at attenuating age-related cognitive decline, however, the effects of this intervention on brain structure and function have not been thoroughly explored.
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There are variations in the interventions, such as location and dosage.
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A standardized assessment battery that captures shared characteristics of mobility and cognition seen in aging and neurodegeneration may increase comparability across research studies, detection of subtle or common reversible factors, and accelerate research progress in dementia, falls, and aging-related disabilities.
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Nutrition is a modifiable factor potentially related to aging.
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The strength of evidence for an association between gait speed and cognition was demonstrated by the number and consistency of results, as well as quality of the studies.
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59/100
In an additional analysis stratifying the sample by weight status, the association between sleep quality and high adherence to the Mediterranean diet was observed only among normal/overweight individuals but not in obese participants.
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Periodontitis is an oral inflammatory disease and may contribute to low-grade systemic inflammation.
From across this tag
9 of the 1,130 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 9. The same 9 appear here every time.
- Can dietary patterns prevent cognitive impairment and reduce Alzheimer's disease risk: Exploring the underlying mechanisms of effects
- Perspectives on Diet and Exercise Interaction for Healthy Aging: Opportunities to Reduce Malnutrition Risk and Optimize Fitness
- Computerized cognitive stimulation and engagement programs in older adults with mild cognitive impairment: comparing feasibility, acceptability, and cognitive and psychosocial effects
- Brain health and exercise in older adults
- Performance-based physical function and future dementia in older people
- Cognitive processes related to gait velocity: results from the Einstein Aging Study
- The Potential of Immersive Virtual Reality for Cognitive Training in Elderly
- Improvement of Cognitive Function after Computer-Based Cognitive Training in Early Stage of Alzheimer's Dementia
- Association of Delirium With Long-term Cognitive Decline: A Meta-analysis