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Nutritional Interventions for the Prevention of Cognitive Decline in Patients With Mild Cognitive Impairment and Alzheimer Disease: Protocol for a Network Meta-Analysis of Randomized Controlled Trials
He Q, Wu KCH, Bennett AN, Zhang JY, Chan KHK.. JMIR research protocols, 2024-02-28
Topic: Risk, prevention and care in population studies
People with MCI are at increased risk of developing AD. Consequently, effective interventions used to decelerate or alleviate the progress of cognitive impairment in older people are a significant focus in geriatric care. Results We included 51 studies, published between 1999 and 2023 (27 studies for AD and 24 studies for MCI) and involving 8420 participants. We plan to finalize the manuscript and publish the comprehensive results by the end of 2024. Conclusions Our study holds significant clinical relevance given the rising prevalence of AD and the potential influence of nutritional interventions on cognitive function in individuals with MCI and AD.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
He, Q., Wu, K. C. H., Bennett, A. N., Zhang, J. Y., & Chan, K. H. K. (2024). Nutritional Interventions for the Prevention of Cognitive Decline in Patients With Mild Cognitive Impairment and Alzheimer Disease: Protocol for a Network Meta-Analysis of Randomized Controlled Trials. JMIR research protocols. https://doi.org/10.2196/47196
Vancouver
He Q, Wu KCH, Bennett AN, Zhang JY, Chan KHK. Nutritional Interventions for the Prevention of Cognitive Decline in Patients With Mild Cognitive Impairment and Alzheimer Disease: Protocol for a Network Meta-Analysis of Randomized Controlled Trials. JMIR research protocols. 2024. doi:10.2196/47196. PMID: 38416536.
BibTeX
@article{he2024-38416536,
author = {He, Q. and Wu, K. C. H. and Bennett, A. N. and Zhang, J. Y. and Chan, K. H. K.},
title = {{Nutritional Interventions for the Prevention of Cognitive Decline in Patients With Mild Cognitive Impairment and Alzheimer Disease: Protocol for a Network Meta-Analysis of Randomized Controlled Trials}},
journal = {JMIR research protocols},
year = {2024},
doi = {10.2196/47196},
pmid = {38416536},
url = {https://doi.org/10.2196/47196}
}
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Key findings
- People with MCI are at increased risk of developing AD.
- Consequently, effective interventions used to decelerate or alleviate the progress of cognitive impairment in older people are a significant focus in geriatric care.
- Results We included 51 studies, published between 1999 and 2023 (27 studies for AD and 24 studies for MCI) and involving 8420 participants.
- We plan to finalize the manuscript and publish the comprehensive results by the end of 2024.
- Conclusions Our study holds significant clinical relevance given the rising prevalence of AD and the potential influence of nutritional interventions on cognitive function in individuals with MCI and AD.
Why it matters
This is a protocol for a network meta-analysis that will compare nutritional interventions for preventing cognitive decline in people with mild cognitive impairment and Alzheimer's disease. No conclusions about which nutritional interventions work are available yet.
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Study details
- Study designsystematic review
- Participants51
- Evidence strengthHigh
How this study scored 52/100
Published in a peer-reviewed journal, and it is a systematic review of all the studies on the question. Scored zero for effect reported because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (JMIR research protocols) |
| Journal's citation record | 0 / 4 | JMIR Research Protocols: journal h-index 62 (OpenAlex, 2026-10-29) |
| Study design | 12 / 12 | A systematic review of all the studies on the question |
| Strength of evidence | 5 / 5 | Rated “high” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2024 — within 3 year(s) of the newest study here |
| Sample size | 1 / 4 | 51 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | A review of other studies — randomisation is not credited here |
| Times cited | 1 / 7 | Cited 3 times (OpenAlex, 2026-10-10) |
| Citations per year | 0 / 5 | 0.8 citations a year over 4 year(s) since 2024 |
| Impact for its field and year | 1 / 6 | Cited 0.2× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 1 / 4 | Cited 3 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 1 / 4 | Last-listed author Kei Hang Katie Chan: h-index 19 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | Brown University: institution h-index 1,120 (OpenAlex) |
| Multi-centre collaboration | 1 / 3 | OpenAlex lists 2 institution(s) in 2 countries |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 38416536) |
| Free to read | 2 / 2 | Free to read |
| Total | 52 / 100 | — |
What each of these 20 components measures, and what this score is not →
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Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
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