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controlled
1,138 studies tagged controlled, dated 1986-09-01 to 2026-09-23. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Alcohol use disorder accelerates age-related cognitive decline 2026-09-23
- A longitudinal study of age-related traits and cognitive function: The Collaborative Amish Aging and Memory Project (CAAMP) 2026-09-20
- Associations of menopause hormone therapy with late-life cognition and brain health vary by formulation and APOEε4 presence 2026-09-20
Studies
1,138 studies carry this tag.
Date range
1986 to 2026
Top journals
- Alzheimer s & Dementia 42
- Neurology 41
- Journal of the American Geriatrics Society 36
- Journal of Alzheimer's disease : JAD 33
- Nutrients 23
437 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Several studies have shown that pharmacological and cognitive treatments for Alzheimers's disease improve cognitive function for short periods, but fewer studies have evaluated the efficacy of those treatments for longer (2-year) periods.
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It was first demonstrated that the differentiation and functioning of cultured brain cells requires not only ALA, but also the very long polyunsaturated omega-3 (DHA) and omega-6 carbon chains.
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Cognitive complaints in older adults may indicate underlying neurodegenerative changes even when unaccompanied by deficits on formal testing.
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By contrast, participants in the highest handgrip strength quartile maintained a higher level of cognitive function.
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Telomere length is a prognostic marker for poststroke cognitive decline, dementia, and death.
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Factor analyses yielded two strong and reliable factors representing underlying physical and cognitive dimensions of IADL.
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People can improve their processing speed at home using readily available technology.
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During follow-up 319 participants developed dementia (221 had AD).
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The authors examined the relationship between cognition and gait velocity, performed with and without interference, in elderly participants.
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Depressive symptoms are cross-sectionally associated with cognitive impairment but not subsequent cognitive decline.
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In humans, age-related memory impairments begin in mid-life and cognitive weakening continues with advancing age.
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There is evidence from a population-based study of an inverse relationship between monounsaturated fatty acids (MUFA) energy intake and age-related cognitive decline (ARCD), while high polyunsaturated fatty acids (PUFA) intake was positively associated with cognitive impairment in elderly subjects.
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Cognitive function and peripheral glucose regulation both decrease with age.
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Cognitive functions and self-reported drinking habits were assessed at 2-year intervals over an average of 7 years of follow-up.
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Our findings suggest that the onset of dementia-related syndromes may be initiated by repetitive cerebral concussions in professional football players.
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To explore neural correlates of cognitive decline in aging, we used longitudinal behavioral data to identify two groups of older adults (n = 40) that differed with regard to whether their performance on tests of episodic memory remained stable or declined over a decade.
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Linking the ADAMS dementia clinical assessment data to the wealth of available longitudinal HRS data on health, health care utilization, informal care, and economic resources and behavior, will provide a unique opportunity to study the onset of CIND and dementia in a nationally representative population-based sample, as well as the risk factors, prevalence, outcomes, and costs of CIND and dementia.
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We examined whether cognitive function at baseline affected cognitive and cardiovascular outcomes in the Study on COgnition and Prognosis in the Elderly (SCOPE), a blood pressure (BP)-lowering intervention trial.
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Little is known about the relative benefits of cognitively stimulating activities at different points in the lifespan.
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In nondemented older persons, executive function is independently associated with tasks of lower extremity function that require high attentional demand.
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Nondemented individuals exhibit a slow rate of whole-brain atrophy from early in adulthood with white-matter loss beginning in middle age; in older adults, the onset of dementia of the Alzheimer type is associated with a markedly accelerated atrophy rate.
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The objective of this study was to examine the relationship between total cholesterol (TC) and cognitive performance within the context of the Framingham Heart Study, a large, community-based, prospective investigation of cardiovascular risk factors.
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A hypothetical construct of "cognitive reserve" is widely used to explain how, in the face of neurodegenerative changes that are similar in nature and extent, individuals vary considerably in the severity of cognitive aging and clinical dementia.
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Essential components of the Mediterranean diet--MUFA, cereals and wine--seem to be protective against cognitive decline.
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For women aged 65 years or older, hormone therapy had an adverse effect on cognition, which was greater among women with lower cognitive function at initiation of treatment.
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Implicit memory, including priming, can be preserved in aging and dementia despite impairment of explicit memory.
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Delirium is a common neurobehavioral syndrome that occurs across health care settings which is associated with adverse outcomes, including death.
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Public Psychiatric Hospital Rekem, Belgium.
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A study was performed on patients with Alzheimer's disease (AD) in order to evaluate the efficacy of a combined treatment (donepezil plus cognitive training) in both cognitive processes and affective states.
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Three-year longitudinal cohort study.
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Contrary to early case-control studies that suggested smoking protects against Alzheimer disease (AD), recent prospective studies have shown that elderly who smoke may be at increased risk for dementia.
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Long follow-up of a general aged population explains several inconsistencies of earlier reports.
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48/100
Individuals over 50 years of age comprise 11% of AIDS cases reported to the Centers for Disease Control and Prevention.
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55/100
Eight hospitals in Baltimore, Maryland.
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A recent Cochrane review of reality orientation therapy identified the need for large, well-designed, multi-centre trials.
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We sought to investigate whether the seropositivity of common infections was associated with cognitive function.
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Among postmenopausal women aged 65 years or older, estrogen plus progestin did not improve cognitive function when compared with placebo.
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In elderly hypertensive patients, a slightly more effective blood pressure reduction during candesartan-based therapy, compared with control therapy, was associated with a modest, statistically non-significant, reduction in major cardiovascular events and with a marked reduction in non-fatal stroke.
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A meta-analytic study was conducted to examine the hypothesis that aerobic fitness training enhances the cognitive vitality of healthy but sedentary older adults.
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53/100
The adverse effects of obesity and hypertension in men are independent and cumulative with respect to cognitive deficit.
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Memory problems are a defining feature of the early stages of Alzheimer's disease (AD) and vascular dementia.
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Performance on a brief cognitive screen on admission was strongly related to subsequent change in function.
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Multifactorial intervention was not effective in preventing falls in older people with cognitive impairment and dementia presenting to the accident and emergency department after a fall.
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Assessment by a speech therapist, staffing ratios, advance directives, fiscal considerations, and specialized dementia units are potentially modifiable factors in nursing homes that may influence the practice of tube feeding in advanced cognitive impairment.
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Recent findings suggest a possible role of diet in age-related cognitive decline, and cognitive impairment of both degenerative (Alzheimer's disease, AD) or vascular origin.
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Training effects were of a magnitude equivalent to the amount of decline expected in elderly persons without dementia over 7- to 14-year intervals.
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64/100
Our study has identified not only risk factors associated with functional decline but also the interactions among these factors.
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Diabetes mellitus is associated with moderate cognitive deficits and neurophysiological and structural changes in the brain, a condition that may be referred to as diabetic encephalopathy.
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Models combining multiple risk factors should refine the prediction of questionable dementia and persistent cognitive impairment, harbingers of dementia.
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The current study sought to determine if discrepancies in quality of education could explain differences in cognitive test scores between African American and White elders matched on years of education.
From across this tag
8 of the 1,130 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 8. The same 8 appear here every time.
- Changes in brain volume and cognition in a randomized trial of exercise and social interaction in a community-based sample of non-demented Chinese elders
- Indicators of Childhood Quality of Education in Relation to Cognitive Function in Older Adulthood
- Neighborhood disadvantage and subjective cognitive function among older Black women
- A brain-computer interface based cognitive training system for healthy elderly: a randomized control pilot study for usability and preliminary efficacy
- Mediterranean Diet, Cognitive Function, and Dementia: A Systematic Review of the Evidence
- Blood cholesterol in late-life and cognitive decline: a longitudinal study of the Chinese elderly
- Cognitive and neuroimaging predictors of instrumental activities of daily living
- Potential Neuroregenerative and Neuroprotective Effects of Uridine/Choline-Enriched Multinutrient Dietary Intervention for Mild Cognitive Impairment: A Narrative Review