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Newest in this topic

  1. Public awareness of the hearing loss-dementia link and self-reported behavioral changes in middle- to older-aged Canadians 2026-09-26
  2. Patterns of modifiable lifestyle, behavioural and health-related risk factors and their associations with incident dementia in UK Biobank 2026-09-25
  3. Excess hypoglycaemia-related hospitalisation in older adults with comorbid type 2 diabetes and dementia: a UK Biobank cohort study 2026-09-16

Studies

1,143 studies carry this tag.

Date range

1978 to 2026

Top journals

  • Neurology 134
  • Alzheimer s & Dementia 52
  • Alzheimer's & dementia : the journal of the Alzheimer's Association 33
  • Journal of the American Geriatrics Society 32
  • JAMA neurology 28

362 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Association of Loneliness With 10-Year Dementia Risk and Early Markers of Vulnerability for Neurocognitive Decline

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. Neurology 2022-02-07 Genetics

    Over 10 years of close clinical dementia surveillance in this cohort study, loneliness was associated with increased dementia risk; this tripled in adults whose baseline risk would otherwise be relatively low on the basis of age and genetic risk, representing a majority of the US population.

  2. Peripheral immunity is associated with the risk of incident dementia

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. Molecular psychiatry 2022-01-25 Long-term cohort studies

    Central immunity components especially microglia in dementia have been well studied and corresponding immunotherapy gradually caught the attention.

  3. Association of serum 25-hydroxyvitamin D concentrations with risk of dementia among individuals with type 2 diabetes: A cohort study in the UK Biobank

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. PLoS medicine 2022-01-13 Long-term cohort studies

    However, due to the synergistic effect between diabetic pathology and neuroinflammation, and the prothrombotic profile in patients with diabetes, whether vitamin D is associated with risk of dementia among patients with diabetes is unclear.

  4. MIND diet and the risk of dementia: a population-based study

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. Alzheimer's research & therapy 2022-01-12 Long-term cohort studies

    Adherence to the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet has been linked to a decreased risk of dementia, but reverse causality and residual confounding by lifestyle may partly account for this link.

  5. Lower serum testosterone concentrations are associated with a higher incidence of dementia in men: The UK Biobank prospective cohort study

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2022-01-03 Long-term cohort studies

    The association of testosterone concentrations with dementia risk remains uncertain.

  6. Association of a MIND Diet with Brain Structure and Dementia in a French Population

    ✓ Peer-reviewed alzhub usefulness score 69 out of 100. The journal of prevention of Alzheimer's disease 2022-01-01 Prevention trials

    In this cohort of French older adults, higher adherence to the French MIND diet was associated with a lower dementia risk and with preserved white matter microstructure.

  7. Digital dementia in the internet generation: excessive screen time during brain development will increase the risk of Alzheimer's disease and related dementias in adulthood

    ✓ Peer-reviewed alzhub usefulness score 42 out of 100. Journal of integrative neuroscience 2022-01-01 Digital health tools

    Emerging evidence suggests that some of these effects are similar to those seen in adults with symptoms of mild cognitive impairment (MCI) in the early stages of dementia, including impaired concentration, orientation, acquisition of recent memories (anterograde amnesia), recall of past memories (retrograde amnesia), social functioning, and self-care.

  8. Effects of Socioeconomic Status and Residence Areas on Long-Term Survival in Patients With Early-Onset Dementia: The Korean National Health Insurance Service Database Study

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. Journal of Korean Medical Science 2022-01-01 Risk factors

    = 0.041). Socioeconomic status and residential area are associated with long-term survival in patients with EOD.

  9. Loneliness, Not Social Support, Is Associated with Cognitive Decline and Dementia Across Two Longitudinal Population-Based Cohorts

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Journal of Alzheimer's disease : JAD 2022-01-01 Long-term cohort studies

    Poor social health is likely associated with cognitive decline and risk of dementia; however, studies show inconsistent results.

  10. Black and White individuals differ in dementia prevalence, risk factors, and symptomatic presentation

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2021-12-02 Disparities

    Despite lower dementia prevalence, Black participants with dementia had more dementia risk factors, as well as greater cognitive impairment and neuropsychiatric symptom severity than White participants.

  11. Dose-response association between device-measured physical activity and incident dementia: a prospective study from UK Biobank

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. BMC Medicine 2021-12-02 Prevention and risk

    After a median follow-up of 6.3 years, 678 individuals were diagnosed with dementia.

  12. Spatiotemporal trends in dementia‐associated deaths, what do the data reveal?

    ✓ Peer-reviewed alzhub usefulness score 37 out of 100. Alzheimer s & Dementia 2021-12-01 Risk factors

    There are factors, other than the step changes in underlying cause of death coding, driving the progressively increasing temporal trend in relative risk of dementia‐associated death.

  13. The impact of built and social environmental characteristics on incidence and estimated risk of dementia

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Alzheimer s & Dementia 2021-12-01 Risk factors

    Associations of neighbourhood NO2 level, walkability, public open space and social fragmentation with dementia incidence and estimated future risk of dementia were statistically significant, indicating the potential to reduce the risk through changes in built and social environments.

  14. The Neutrophil to Lymphocyte Ratio Is Associated With the Risk of Subsequent Dementia in the Framingham Heart Study

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. Frontiers in aging neuroscience 2021-11-30 Long-term cohort studies

    The objective of this study was to investigate whether increased NLR in older adults is independently associated with the risk of subsequent dementia.

  15. Consumption of coffee and tea and risk of developing stroke, dementia, and poststroke dementia: A cohort study in the UK Biobank

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. PLoS medicine 2021-11-16 Prevention and risk

    Intake of coffee alone or in combination with tea was associated with lower risk of poststroke dementia.

  16. Association of Reproductive History With Brain MRI Biomarkers of Dementia Risk in Midlife

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Neurology 2021-11-03 Genetics

    Reproductive history events signaling more estrogen exposure such as premenopausal status, longer reproductive span, higher number of children, and use of HT and HC were associated with larger GMV in women in midlife.

  17. Relationship between Fried's frailty phenotype and oral frailty in long-term care residents

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. Age and ageing 2021-11-01 Digital health tools

    Design the FINnish ORAL Health Study in Long-Term Care study is a cross-sectional clinical research comprising findings on oral and general health and nutrition.

  18. Environmental factors and risks of cognitive impairment and dementia: A systematic review and meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. Ageing research reviews 2021-10-29 Disparities

    This review highlights that air pollutions, especially PM 2.5 and NO 2 play important role in the risk for age-related cognitive impairment and dementia.

  19. Relationship between Residential Segregation, Later-Life Cognition, and Incident Dementia across Race/Ethnicity

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. International journal of environmental research and public health 2021-10-26 Disparities

    Systemic racism leads to racial/ethnic residential segregation, which can result in health inequities.

  20. Modifiable risk factors for dementia and dementia risk profiling. A user manual for Brain Health Services-part 2 of 6

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. Alzheimer's research & therapy 2021-10-11 Digital health tools

    Rare variants should only be investigated in users with a family history of early-onset dementia in a first degree relative.

  21. Cardiometabolic risk factors associated with brain age and accelerate brain ageing

    ✓ Peer-reviewed alzhub usefulness score 61 out of 100. Human brain mapping 2021-10-09 Digital health tools

    The structure and integrity of the ageing brain is interchangeably linked to physical health, and cardiometabolic risk factors (CMRs) are associated with dementia and other brain disorders.

  22. Shingles, Zostavax vaccination and risk of developing dementia: a nested case-control study-results from the UK Biobank cohort

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. BMJ open 2021-10-08 Long-term cohort studies

    Data were drawn from the UK Biobank cohort study with a total of 228 223 participants with Hospital Episodes Statistics and primary care linkage health records.

  23. Association of Short and Long Sleep Duration With Amyloid-β Burden and Cognition in Aging

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. JAMA neurology 2021-10-01 Genetics

    The 4417 participants in the study included 2618 women (59%) and had a mean (SD) age of 71.3 (4.7) years.

  24. Type 2 diabetes is associated with increased risks of cognitive dysfunction and brain abnormalities.

  25. Associations of ophthalmic and systemic conditions with incident dementia in the UK Biobank

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. The British journal of ophthalmology 2021-09-13 Long-term cohort studies

    Our analysis included 12 364 adults aged 55-73 years from the UK Biobank cohort.

  26. Association Between Midlife Obesity and Its Metabolic Consequences, Cerebrovascular Disease, and Cognitive Decline

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. The Journal of clinical endocrinology and metabolism 2021-09-01 Long-term cohort studies

    Chronic obesity is associated with several complications, including cognitive impairment and dementia.

  27. Obstructive sleep apnea treatment and dementia risk in older adults

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Sleep 2021-09-01 Disparities

    Study objectives To examine associations between positive airway pressure (PAP) therapy, adherence and incident diagnoses of Alzheimer's disease (AD), mild cognitive impairment (MCI), and dementia not otherwise specified (DNOS) in older adults.

  28. Plasma proteins, cognitive decline, and 20-year risk of dementia in the Whitehall II and Atherosclerosis Risk in Communities studies

    ✓ Peer-reviewed alzhub usefulness score 61 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2021-08-02 Long-term cohort studies

    Plasma proteins affect biological processes and are common drug targets but their role in the development of Alzheimer's disease and related dementias remains unclear.

  29. Speech-in-noise hearing impairment is associated with an increased risk of incident dementia in 82,039 UK Biobank participants

    ✓ Peer-reviewed alzhub usefulness score 56 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2021-07-21 Digital health tools

    SiN hearing impairment is independently associated with incident dementia, providing further evidence for hearing impairment as a potential modifiable dementia risk factor.

  30. Increased risk for dementia in neurofibromatosis type 1

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. Genetics in medicine : official journal of the American College of Medical Genetics 2021-07-15 Health systems and care delivery

    To determine the risk for dementia in neurofibromatosis type 1 (NF1) using a Finnish nationwide cohort of individuals with NF1, and data from national registries.

  31. Meat consumption and risk of incident dementia: cohort study of 493,888 UK Biobank participants

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. The American journal of clinical nutrition 2021-07-01 Genetics

    Worldwide, the prevalence of dementia is increasing and diet as a modifiable factor could play a role.

  32. The rate of hospital admissions are variable between GP practices, with deprivation and being admitted from home as risk factors for admission for ACSC and non-ACSC admissions.

  33. Hospital-treated infectious diseases and the risk of dementia: a large, multicohort, observational study with a replication cohort

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. The Lancet. Infectious diseases 2021-06-21 Caregiving

    Existing studies have included a narrow range of infectious diseases, relied on short follow-up periods, and provided little evidence for whether the increased risk is limited to specific dementia subtypes or attributable to specific microbes rather than infection burden.

  34. The role of diet on the risk of dementia in the oldest old: The Monzino 80-plus population-based study

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Clinical nutrition (Edinburgh, Scotland) 2021-06-18 Prevention trials

    Oldest-old eating less and having diets with less variety and nutrient density were more frequent among subjects with dementia.

  35. Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic study

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. PLoS medicine 2021-05-27 Brain scans and imaging

    We tested whether dysregulation of cholesterol catabolism, through its conversion to primary bile acids (BAs), was associated with dementia pathogenesis.

  36. Sex differences in the association between major cardiovascular risk factors in midlife and dementia: a cohort study using data from the UK Biobank

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. BMC medicine 2021-05-19 Long-term cohort studies

    Sex differences in major cardiovascular risk factors for incident (fatal or non-fatal) all-cause dementia were assessed in the UK Biobank.

  37. Sarcopenia is associated with incident Alzheimer's dementia, mild cognitive impairment, and cognitive decline

    ✓ Peer-reviewed alzhub usefulness score 56 out of 100. Journal of the American Geriatrics Society 2021-05-05 Brain tissue and pathology

    We examined whether sarcopenia is associated with the occurrence of late-life cognitive impairment.

  38. Herpes simplex virus 1 and the risk of dementia: a population-based study

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Scientific reports 2021-04-22 Long-term cohort studies

    Herpes simplex virus 1 (HSV1) is a neuroinvasive virus capable of entering the brain which makes it a candidate pathogen for increasing risk of dementia.

  39. Dementia is an age-independent risk factor for severity and death in COVID-19 inpatients

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2021-04-21 Long-term cohort studies

    Dementia has been associated with COVID-19 prevalence, but whether this reflects higher infection, older age of patients, or disease severity remains unclear.

  40. Association of sleep duration in middle and old age with incidence of dementia

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. Nature communications 2021-04-20 How common it is

    Sleep dysregulation is a feature of dementia but it remains unclear whether sleep duration prior to old age is associated with dementia incidence.

  41. Association of sleep duration in middle and old age with incidence of dementia

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. Nature Communications 2021-04-20 Prevention and risk

    Using nearly 8,000 British civil servants followed for up to 25 years (the Whitehall II study), this study found that people who slept 6 hours or less per night in their 50s and 60s had a higher later risk of dementia than those sleeping about 7 hours, even after accounting for other health and social factors.

  42. Association Between Age at Diabetes Onset and Subsequent Risk of Dementia

    ✓ Peer-reviewed alzhub usefulness score 77 out of 100. JAMA 2021-04-01 Risk factors

    Among 10 095 participants (67.3% men; aged 35-55 years in 1985-1988), a total of 1710 cases of diabetes and 639 cases of dementia were recorded over a median follow-up of 31.7 years.

  43. Is neuroticism differentially associated with risk of Alzheimer's disease, vascular dementia, and frontotemporal dementia?

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Journal of psychiatric research 2021-03-25 Long-term cohort studies

    This study examines whether neuroticism is differentially associated with risk of incident Alzheimer's disease (AD), vascular dementia (VD), and frontotemporal dementia (FTD) using a prospective study design.

  44. Associations of loneliness with risk of Alzheimer's disease dementia in the Framingham Heart Study

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2021-03-24 Long-term cohort studies

    The relationship between persistent loneliness and Alzheimer's disease (AD) is unclear.

  45. Midlife vascular risk factors and risk of incident dementia: Longitudinal cohort and Mendelian randomization analyses in the UK Biobank

    ✓ Peer-reviewed alzhub usefulness score 61 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2021-03-22 Prevention and risk

    These findings underscore the importance of blood pressure control in midlife to mitigate dementia risk.

  46. Mediterranean diet and risk for dementia and cognitive decline in a Mediterranean population

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. Journal of the American Geriatrics Society 2021-03-16 Prevention trials

    In the present study, higher adherence to MeDi was associated with a reduced risk for dementia and cognitive decline in a traditional Mediterranean population.

  47. Head injury and 25-year risk of dementia

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2021-03-09 Disparities

    Head injury was associated with risk of dementia (hazard ratio [HR] = 1.44, 95% confidence interval [CI] = 1.3-1.57), with evidence of dose-response (1 head injury: HR = 1.25, 95% CI = 1.13-1.39, 2+ head injuries: HR = 2.14, 95% CI = 1.86-2.46).

  48. Mediterranean Diet and Risk of Dementia and Alzheimer's Disease in the EPIC-Spain Dementia Cohort Study

    ✓ Peer-reviewed alzhub usefulness score 76 out of 100. Nutrients 2021-02-22 Prevention trials

    The Mediterranean diet (MD) has shown to reduce the occurrence of several chronic diseases.

  49. Neighborhood Sidewalk Environment and Incidence of Dementia in Older Japanese Adults

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. American Journal of Epidemiology 2021-02-17 Risk factors

    Sidewalks are indispensable environmental resources for daily life in that they encourage physical activity.

  50. Is personality associated with dementia risk? A meta-analytic investigation

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. Ageing research reviews 2021-02-06 Disparities

    This study provides a quantitative synthesis of the prospective associations between personality traits (neuroticism, extraversion, openness, agreeableness, conscientiousness) and the risk of incident Alzheimer's disease and related dementias.

From across this tag

10 of the 1,134 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

All topic tags with their study counts