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Newest in this topic

  1. Public awareness of the hearing loss-dementia link and self-reported behavioral changes in middle- to older-aged Canadians 2026-09-26
  2. Patterns of modifiable lifestyle, behavioural and health-related risk factors and their associations with incident dementia in UK Biobank 2026-09-25
  3. Excess hypoglycaemia-related hospitalisation in older adults with comorbid type 2 diabetes and dementia: a UK Biobank cohort study 2026-09-16

Studies

1,143 studies carry this tag.

Date range

1978 to 2026

Top journals

  • Neurology 134
  • Alzheimer s & Dementia 52
  • Alzheimer's & dementia : the journal of the Alzheimer's Association 33
  • Journal of the American Geriatrics Society 32
  • JAMA neurology 28

362 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Long-term exposure to ambient air pollution and risk of dementia: Results of the prospective Three-City Study

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Environment international 2021-01-20 Disparities

    In this large cohort of older adults, long-term PM2.5 exposure was associated with increased dementia incidence.

  2. The Association between Vision Impairment and Incidence of Dementia and Cognitive Impairment: A Systematic Review and Meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 73 out of 100. Ophthalmology 2021-01-08 Prevention and risk

    Topic The magnitude and direction of the association between vision impairment and incident dementia and cognitive impairment in prospective cohort studies was estimated by systematic review and meta-analysis.

  3. Multimorbidity burden and dementia risk in older adults: The role of inflammation and genetics

    ✓ Peer-reviewed alzhub usefulness score 56 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2021-01-06 Prevention and risk

    Individuals with neuropsychiatric, cardiovascular, and sensory impairment/cancer patterns are at increased risk for dementia and APOE ε4, and inflammation may further increase the risk.

  4. Assessment of Advanced Glycation End Products and Receptors and the Risk of Dementia

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. JAMA network open 2021-01-04 Long-term cohort studies

    Advanced glycation end products (AGEs) and their receptor (RAGE) are implicated in the pathophysiological processes of dementia and potentially underlie the association of diabetes with neurodegeneration.

  5. High Blood Pressure and Risk of Dementia: A Two-Sample Mendelian Randomization Study in the UK Biobank

    ✓ Peer-reviewed alzhub usefulness score 68 out of 100. Biological psychiatry 2020-12-27 Long-term cohort studies

    We tested the hypothesis that a causal relationship exists between systolic BP (SBP) and/or diastolic BP (DBP) and risk of Alzheimer's disease (AD).

  6. Estimates of the Association of Dementia With US Mortality Levels Using Linked Survey and Mortality Records

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. JAMA neurology 2020-12-01 Disparities

    Of the 7342 total sample, 4348 participants (60.3%) were women.

  7. Prevalence, risk factors, and management of dementia and mild cognitive impairment in adults aged 60 years or older in China: a cross-sectional study

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. The Lancet. Public health 2020-12-01 Prevention and risk

    Overall age-adjusted and sex-adjusted prevalence was estimated to be 6·0% (95% CI 5·8-6·3) for dementia, 3·9% (3·8-4·1) for Alzheimer's disease, 1·6% (1·5-1·7) for vascular dementia, and 0·5% (0·5-0·6) for other dementias.

  8. Circadian disturbances in Alzheimer's disease progression: a prospective observational cohort study of community-based older adults

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. The lancet. Healthy longevity 2020-11-12 Mild cognitive impairment

    We used Cox proportional hazards models and logistic regressions to assess whether circadian disturbances predict an increased risk of incident Alzheimer's dementia and conversion of mild cognitive impairment to Alzheimer's dementia.

  9. Bidirectional associations between COVID-19 and psychiatric disorder: retrospective cohort studies of 62 354 COVID-19 cases in the USA

    ✓ Peer-reviewed alzhub usefulness score 72 out of 100. The lancet. Psychiatry 2020-11-09 Getting a diagnosis

    Although preliminary, our findings have implications for clinical services, and prospective cohort studies are warranted.

  10. Associations between physical frailty and dementia incidence: a prospective study from UK Biobank

    ✓ Peer-reviewed alzhub usefulness score 58 out of 100. The lancet. Healthy longevity 2020-11-02 Prevention and risk

    Of 502 535 participants in UK Biobank, 143 215 met the inclusion criteria and were included in our analyses. 68 500 (47·8%) of the participants were pre-frail and 5565 (3·9%) were frail.

  11. Bi-directional association between epilepsy and dementia: The Framingham Heart Study

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. Neurology 2020-10-23 Long-term cohort studies

    We analyzed prospectively collected data in the Original and Offspring FHS cohorts.

  12. Dementia in late-onset epilepsy: The Atherosclerosis Risk in Communities study

    ✓ Peer-reviewed alzhub usefulness score 61 out of 100. Neurology 2020-10-23 Disparities

    Of 9,033 ARIC participants with sufficient Medicare coverage data (4,980 [55.1%] female, 1993 [22.1%] Black), 671 met the definition of LOE.

  13. The Effects of COVID-19 and Quarantine Measures on the Lifestyles and Mental Health of People Over 60 at Increased Risk of Dementia

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Frontiers in psychiatry 2020-10-14 Prevention trials

    The sample included 55.6% patients with MCI and 56 people with SCD.

  14. Genetic Risk of Alzheimer's Disease and Sleep Duration in Non-Demented Elders

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. Annals of neurology 2020-10-05 Long-term cohort studies

    Growing evidence has suggested an association between sleep duration and Alzheimer's disease (AD), but it is unclear if sleep duration is a manifestation of the AD disease process.

  15. Association of midlife vascular risk and AD biomarkers with subsequent cognitive decline

    ✓ Peer-reviewed alzhub usefulness score 61 out of 100. Neurology 2020-09-28 Tau biomarkers

    At baseline, participants (n = 168) were cognitively normal and primarily middle-aged (mean 56.4 years, SD 10.9 years) and had both vascular risk factor status and proximal CSF biomarkers available.

  16. Metformin Use Is Associated With Slowed Cognitive Decline and Reduced Incident Dementia in Older Adults With Type 2 Diabetes: The Sydney Memory and Ageing Study

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Diabetes care 2020-09-23 Vascular contributions

    Older people with diabetes receiving metformin have slower cognitive decline and lower dementia risk.

  17. Vitamin D intake is associated with dementia risk in the Washington Heights-Inwood Columbia Aging Project (WHICAP)

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2020-09-13 Prevention trials

    Higher vitamin D intake is associated with decreased risk of dementia in a multiethnic cohort.

  18. Estrogen-dependent hippocampal wiring as a risk factor for age-related dementia in women

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Progress in neurobiology 2020-08-08 Prevention trials

    Women are more prone than men to develop age-related dementia, such as Alzheimer's disease (AD).

  19. Hcbs Service Intensity and Nursing Home Placement for Patients with Alzheimer's Disease and Related Dementias: Does Race Matter?

    ✓ Peer-reviewed alzhub usefulness score 31 out of 100. Health Services Research 2020-08-01 Risk factors

    The overall NH admission rate among HCBS users with ADRD was 67%, 55%, and 36% for whites, blacks, and others, respectively.

  20. Higher risk of dementia in English older individuals who are overweight or obese

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. International journal of epidemiology 2020-08-01 Prevention and risk

    Our results suggest that having an increased body weight or abdominal obesity are associated with increased dementia incidence.

  21. Cardiovascular health, genetic risk, and risk of dementia in the Framingham Heart Study

    ✓ Peer-reviewed alzhub usefulness score 56 out of 100. Neurology 2020-07-20 Long-term cohort studies

    We categorized CVH on the basis of the American Heart Association Ideal CVH Index and genetic risk through a genetic risk score (GRS) of common genetic variants and the APOE ε4 genotype in 1,211 Framingham Heart Study (FHS) offspring cohort participants.

  22. Cardiovascular risk factors and accelerated cognitive decline in midlife: The CARDIA Study

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Neurology 2020-07-15 Disparities

    Midlife CVRFs, especially hypertension, diabetes mellitus, and smoking, are common and associated with accelerated cognitive decline at midlife.

  23. Late-Life Depression Is Associated With Reduced Cortical Amyloid Burden: Findings From the Alzheimer's Disease Neuroimaging Initiative Depression Project

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. Biological psychiatry 2020-07-02 Long-term cohort studies

    Thirty-three percent of LLD participants met ADNI criteria for mild cognitive impairment.

  24. Association Between Cardiovascular Disease and Long-term Exposure to Air Pollution With the Risk of Dementia

    ✓ Peer-reviewed alzhub usefulness score 74 out of 100. JAMA neurology 2020-07-01 Vascular contributions

    This study found that long-term exposure to air pollution was associated with a higher risk of dementia.

  25. Twenty-seven-year time trends in dementia incidence in Europe and the United States: The Alzheimer Cohorts Consortium

    ✓ Peer-reviewed alzhub usefulness score 82 out of 100. Neurology 2020-07-01 How common it is

    The incidence rate of dementia in Europe and North America has declined by 13% per decade over the past 25 years, consistently across studies.

  26. Actigraphy-estimated sleep and 24-hour activity rhythms and the risk of dementia

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2020-06-19 Long-term cohort studies

    During follow-up, 60 individuals developed dementia, of which 49 had Alzheimer's disease (AD).

  27. Healthy lifestyle and the risk of Alzheimer dementia: Findings from 2 longitudinal studies

    ✓ Peer-reviewed alzhub usefulness score 77 out of 100. Neurology 2020-06-17 Prevention and risk

    A healthy lifestyle as a composite score is associated with a substantially lower risk of Alzheimer's dementia.

  28. Of 157 participants initially assessed, 137 were enrolled in the Age-Well clinical trial, and 127 were analyzed in this study.

  29. Association of body mass index with risk of cognitive impairment and dementia: A systematic review and meta-analysis of prospective studies

    ✓ Peer-reviewed alzhub usefulness score 65 out of 100. Neuroscience and biobehavioral reviews 2020-05-30 Prevention and risk

    Controversies persist about the associations of body mass index (BMI) with risk of cognitive impairment and dementia.

  30. Blood Pressure and Risks of Cognitive Impairment and Dementia: A Systematic Review and Meta-Analysis of 209 Prospective Studies

    ✓ Peer-reviewed alzhub usefulness score 69 out of 100. Hypertension (Dallas, Tex. : 1979) 2020-05-26 Risk factors

    Controversies persist regarding the association between blood pressure (BP) and the risks of cognitive impairment and dementia due to inconsistent definitions of BP exposure and varying population characteristics.

  31. Association of Blood Pressure Lowering With Incident Dementia or Cognitive Impairment: A Systematic Review and Meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 85 out of 100. JAMA 2020-05-19 Prevention and risk

    In this meta-analysis of randomized clinical trials, blood pressure lowering with antihypertensive agents compared with control was significantly associated with a lower risk of incident dementia or cognitive impairment.

  32. Albuminuria and Estimated GFR as Risk Factors for Dementia in Midlife and Older Age: Findings From the ARIC Study

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. American journal of kidney diseases : the official journal of the National Kidney Foundation 2020-05-16 Long-term cohort studies

    & objective Evidence is limited on how estimated glomerular filtration rate (eGFR) and urinary albumin-creatinine ratio (UACR) relate to dementia at different ages.

  33. Motoric Cognitive Risk Syndrome: A Risk Factor for Cognitive Impairment and Dementia in Different Populations

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Annals of geriatric medicine and research 2020-03-24 Clinical safety

    Changes in gait, especially decreased gait velocity, may be a harbinger of cognitive decline in aging.

  34. Prevalence, Risk Factors, and Complications of Oropharyngeal Dysphagia in Older Patients with Dementia

    ✓ Peer-reviewed alzhub usefulness score 69 out of 100. Nutrients 2020-03-24 Clinical safety

    The prevalence of older patients with dementia and oropharyngeal dysphagia (OD) is rising and management is poor.

  35. Association between socioeconomic status and the development of mental and physical health conditions in adulthood: a multi-cohort study

    ✓ Peer-reviewed alzhub usefulness score 73 out of 100. The Lancet. Public health 2020-01-31 Prevention and risk

    During 1 110 831 person-years at risk, we recorded 245 573 hospitalisations in the Finnish cohorts; the corresponding numbers in the UK study were 60 946 hospitalisations in 186 572 person-years.

  36. Dietary flavonols and risk of Alzheimer dementia

    ✓ Peer-reviewed alzhub usefulness score 65 out of 100. Neurology 2020-01-29 Genetics

    Higher dietary intakes of flavonols may be associated with reduced risk of developing Alzheimer dementia.

  37. Prospective Associations Between Diffusion Tensor Imaging Parameters and Frailty in Older Adults

    ✓ Peer-reviewed alzhub usefulness score 63 out of 100. Journal of the American Geriatrics Society 2020-01-25 Treatments

    This is the first study to show that WM integrity is associated with frailty in older adults.

  38. Circulating Vitamin D Levels and Alzheimer's Disease: A Mendelian Randomization Study in the IGAP and UK Biobank

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Journal of Alzheimer's disease : JAD 2020-01-01 Long-term cohort studies

    Observational studies strongly supported the association of low levels of circulating 25-hydroxyvitamin D (25OHD) and cognitive impairment or dementia in aging populations.

  39. Cognitive Impairment Is a Common Comorbidity in Deceased COVID-19 Patients: A Hospital-Based Retrospective Cohort Study

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Journal of Alzheimer's disease : JAD 2020-01-01 End-of-life care

    We analyzed the frequency of cognitive impairment (CI) in deceased COVID-19 patients at a tertiary hospital in Spain.

  40. Type 2 Diabetes Interacts With Alzheimer Disease Risk Factors to Predict Functional Decline

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. Alzheimer disease and associated disorders 2020-01-01 Tau biomarkers

    The current study examined the interactive effect of type 2 diabetes and Alzheimer disease (AD) risk factors on the rate of functional decline in cognitively normal participants from the Alzheimer's Disease Neuroimaging Initiative.

  41. Sleep problems and risk of all-cause cognitive decline or dementia: an updated systematic review and meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 68 out of 100. Journal of neurology, neurosurgery, and psychiatry 2019-12-26 Prevention and risk

    Sleep management might serve as a promising target for dementia prevention.

  42. Associations of Regional Brain Structural Differences With Aging, Modifiable Risk Factors for Dementia, and Cognitive Performance

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. JAMA network open 2019-12-02 Long-term cohort studies

    Identifying brain regions associated with risk factors for dementia could guide mechanistic understanding of risk factors associated with Alzheimer disease (AD).

  43. Associations of dietary choline intake with risk of incident dementia and with cognitive performance: the Kuopio Ischaemic Heart Disease Risk Factor Study

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. The American journal of clinical nutrition 2019-12-01 Genetics

    Higher phosphatidylcholine intake was associated with lower risk of incident dementia and better cognitive performance in men in eastern Finland.

  44. Antihypertensive medications and risk for incident dementia and Alzheimer's disease: a meta-analysis of individual participant data from prospective cohort studies

    ✓ Peer-reviewed alzhub usefulness score 74 out of 100. The Lancet. Neurology 2019-11-06 Prevention and risk

    Over a long period of observation, no evidence was found that a specific AHM drug class was more effective than others in lowering risk of dementia.

  45. Relationship of Cigarette Smoking and Time of Quitting with Incident Dementia and Cognitive Decline

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. Journal of the American Geriatrics Society 2019-11-01 Long-term cohort studies

    Understanding how dementia risk is impacted by timing of smoking cessation has public health implications for prevention efforts.

  46. Gray Matter Age Prediction as a Biomarker for Risk of Dementia

    ✓ Peer-reviewed alzhub usefulness score 58 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2019-10-01 Long-term cohort studies

    The gap between predicted brain age using magnetic resonance imaging (MRI) and chronological age may serve as a biomarker for early-stage neurodegeneration.

  47. Genetic predisposition, modifiable-risk-factor profile and long-term dementia risk in the general population

    ✓ Peer-reviewed alzhub usefulness score 63 out of 100. Nature medicine 2019-08-26 Prevention and risk

    The exact etiology of dementia is still unclear, but both genetic and lifestyle factors are thought to be key drivers of this complex disease.

  48. Diabetes mellitus and risks of cognitive impairment and dementia: A systematic review and meta-analysis of 144 prospective studies

    ✓ Peer-reviewed alzhub usefulness score 69 out of 100. Ageing research reviews 2019-08-17 How common it is

    Diabetes, even prediabetes and changes of diabetes-related biochemical indicators, predicted increased incidence of cognitive impairment and dementia.

  49. Association of ideal cardiovascular health at age 50 with incidence of dementia: 25 year follow-up of Whitehall II cohort study

    ✓ Peer-reviewed alzhub usefulness score 72 out of 100. BMJ (Clinical research ed.) 2019-08-07 Prevention and risk

    Adherence to the Life Simple 7 ideal cardiovascular health recommendations in midlife was associated with a lower risk of dementia later in life.

  50. Association of social contact with dementia and cognition: 28-year follow-up of the Whitehall II cohort study

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. PLoS Medicine 2019-08-02 Prevention and risk

    More frequent social contact at age 60 years was associated with lower dementia risk (hazard ratio [HR] for each SD higher social contact frequency = 0.88 [95% CI 0.79, 0.98], p = 0.02); effect size of the association of social contact at 50 or 70 years with dementia was similar (0.92 [95% CI 0.83, 1.02], p = 0.13 and 0.91 [95% CI 0.78, 1.06], p = 0.23, respectively) but not statistically significant.

From across this tag

10 of the 1,134 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

All topic tags with their study counts