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blood-biomarkers
8 studies tagged blood-biomarkers, dated 2022-11-24 to 2025-05-22. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Blood biomarkers of Alzheimer's disease and 12-year muscle strength trajectories in community-dwelling older adults: a cohort study 2025-05-22
- Differences in Alzheimer's disease blood biomarker stability: Implications for the use of tau/amyloid ratios 2025-04-01
- Blood biomarkers differentiate AD-related versus non-AD-related cognitive deficits 2025-03-01
Studies
8 studies carry this tag.
Date range
2022 to 2025
Top journals
- Alzheimer's & dementia : the journal of the Alzheimer's Association 4
- Alzheimer's research & therapy 1
- Journal of geriatric psychiatry and neurology 1
- The lancet. Healthy longevity 1
- Translational psychiatry 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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In adjusted models, higher concentrations of p-tau181 (β per year 0·93 [95% CI 0·71 to 1·16]; p<0·0001), p-tau217 (β per year 1·31 [1·03 to 1·58]; p<0·0001), neurofilament light chain (β per year 0·76 [0·56 to 0·96]; p<0·0001), and GFAP (β per year 0·37 [0·21 to 0·53]; p<0·0001) were associated with an accelerated decline of chair-stand performance over time.
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Differences in the stability of Aβ42 and p-tau217 may lead to altered p-tau217/Aβ42 ratio results if samples are not handled properly during the pre-analytical testing phase.
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Blood-based biomarkers may differentiate non-AD-related versus AD-related cognitive deficits.
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Plasma biomarkers of dementia, including phosphorylated tau (p-tau217), offer promise as tools for diagnosis, stratification for clinical trials, monitoring disease progression, and assessing the success of interventions in those living with Alzheimer's disease.
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In the community, the concentration of AD blood biomarkers varies in relation to medical conditions and systemic inflammation.
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In community and clinical settings, SCC predict both dementia and depression in the absence of dementia.
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Our findings suggest that, among PSEN1 mutation carriers, females had a greater rate of neurodegeneration than males, yet it did not predict cognitive performance.
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Encouraging results were found for several biomarkers, alone or in combination.