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70/100

✓ Peer-reviewed alzhub usefulness score 70 out of 100. Disparities

Topic: Risk, prevention and care in population studies

Importance Hearing and vision problems are individually associated with increased dementia risk, but the impact of having concurrent hearing and vision deficits, ie, dual sensory impairment (DSI), on risk of dementia, including its major subtypes Alzheimer disease (AD) and vascular dementia (VaD), is not well known. Objective To evaluate whether DSI is associated with incident dementia in older adults. Design, setting, and participants This prospective cohort study from the Cardiovascular Health Study (CHS) was conducted between 1992 and 1999, with as many as 8 years of follow-up. The multicenter, population-based sample was recruited from Medicare eligibility files in 4 US communities with academic medical centers. Of 5888 participants aged 65 years and older in CHS, 3602 underwent cranial magnetic resonance imaging and completed the modified Mini-Mental State Examination in 1992 to 1994 as part of the CHS Cognition Study. A total of 227 participants were excluded due to prevalent dementia, leaving a total of 3375 participants without dementia at study baseline. The study hypothesis was that DSI would be associated with increased risk of dementia compared with no sensory impairment. The association between the duration of DSI with risk of dementia was also evaluated. Data analysis was conducted from November 2019 to February 2020. Exposures Hearing and vision impairments were collected via self-report at baseline and as many as 5 follow-up visits. Main outcomes and measures All-cause dementia, AD, and VaD, classified by a multidisciplinary committee using standardized criteria. Results A total of 2927 participants with information on hearing and vision at all available study visits were included in the analysis (mean [SD] age, 74.6 [4.8] years; 1704 [58.2%] women; 455 [15.5%] African American or Black; 2472 [85.5%] White). Compared with no sensory impairment, DSI was associated with increased risk of all-cause dementia (hazard ratio [HR], 2.60; 95% CI, 1.66-2.06; P Conclusions and relevance In this cohort study, DSI was associated with increased risk of dementia, particularly AD. Evaluation of hearing and vision in older adults may help to identify those at high risk of developing dementia.

Cite this study APA, Vancouver, BibTeX · download .bib or .ris

APA 7th

Hwang, P. H., Longstreth, W. T., Thielke, S. M., Francis, C. E., Carone, M., Kuller, L. H., et al. (2022). Longitudinal Changes in Hearing and Visual Impairments and Risk of Dementia in Older Adults in the United States. JAMA network open. https://doi.org/10.1001/jamanetworkopen.2022.10734

Vancouver

Hwang PH, Longstreth WT, Thielke SM, Francis CE, Carone M, Kuller LH, et al. Longitudinal Changes in Hearing and Visual Impairments and Risk of Dementia in Older Adults in the United States. JAMA network open. 2022. doi:10.1001/jamanetworkopen.2022.10734. PMID: 35511175.

BibTeX

@article{hwang2022-35511175,
  author  = {Hwang, P. H. and Longstreth, W. T. and Thielke, S. M. and Francis, C. E. and Carone, M. and Kuller, L. H. and Fitzpatrick, A. L.},
  title   = {{Longitudinal Changes in Hearing and Visual Impairments and Risk of Dementia in Older Adults in the United States}},
  journal = {JAMA network open},
  year    = {2022},
  doi     = {10.1001/jamanetworkopen.2022.10734},
  pmid    = {35511175},
  url     = {https://doi.org/10.1001/jamanetworkopen.2022.10734}
}

Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record names 7 authors; APA and Vancouver show the first six, BibTeX and the downloads carry all of them. Check the citation against the original before you use it.

Key findings

Importance Hearing and vision problems are individually associated with increased dementia risk, but the impact of having concurrent hearing and vision deficits, ie, dual sensory impairment (DSI), on risk of dementia, including its major subtypes Alzheimer disease (AD) and vascular dementia (VaD), is not well known.
Objective To evaluate whether DSI is associated with incident dementia in older adults.
The study hypothesis was that DSI would be associated with increased risk of dementia compared with no sensory impairment.
Results A total of 2927 participants with information on hearing and vision at all available study visits were included in the analysis (mean [SD] age, 74.6 [4.8] years; 1704 [58.2%] women; 455 [15.5%] African American or Black; 2472 [85.5%] White).
Compared with no sensory impairment, DSI was associated with increased risk of all-cause dementia (hazard ratio [HR], 2.60; 95% CI, 1.66-2.06; P Conclusions and relevance In this cohort study, DSI was associated with increased risk of dementia, particularly AD.

Why it matters

This prospective cohort study evaluated whether dual sensory impairment (concurrent hearing and vision deficits) is associated with incident dementia in older adults. It is an observational study of sensory impairment and dementia risk, not a test of any treatment, cure, or prevention.

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Study details

Study designcohort study
Participants5,888
Effect size58.2%; 15.5%; 85.5%
Evidence strengthModerate

How this study scored 70/100

Published in a leading specialty journal, and it is a cohort study following people over time. Scored zero for randomised / blinded because the record does not state it.

Component	Points	Why
Journal tier	9 / 10	Tier 2 — leading specialty journal (JAMA network open)
Journal's citation record	2 / 4	JAMA Network Open: journal h-index 235 (OpenAlex, 2026-10-29)
Study design	7 / 12	A cohort study following people over time
Strength of evidence	3 / 5	Rated “moderate” in our summary
Peer-review validation	10 / 10	Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent	3 / 5	2022 — within 6 year(s) of the newest study here
Sample size	3 / 4	5,888 participants
Effect reported	2 / 3	Effect reported as a number, without an interval or test
Studied in people	3 / 3	Studied in people (participant count stated)
Randomised / blinded	0 / 2	No randomisation or blinding stated — scores zero (not stated in the record — scored 0)
Times cited	4 / 7	Cited 68 times (OpenAlex, 2026-10-10)
Citations per year	3 / 5	11.3 citations a year over 6 year(s) since 2022
Impact for its field and year	4 / 6	Cited 8.1× the average for papers of its field and year (OpenAlex FWCI)
Cited by studies here	2 / 6	Cited by 4 other studies in this library
Still being cited	3 / 4	Cited 58 times in 2024–2026 (2026 still in progress; OpenAlex)
Senior author's track record	3 / 4	Last-listed author Annette L. Fitzpatrick: h-index 53 (OpenAlex, whole career)
Institution's track record	3 / 3	University of Washington: institution h-index 3,540 (OpenAlex)
Multi-centre collaboration	2 / 3	OpenAlex lists 4 institution(s) in 1 country
Indexed in PubMed	2 / 2	Indexed in PubMed (PMID 35511175)
Free to read	2 / 2	Free to read
Total	70 / 100	—

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