Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
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43/100
This small non-randomized study is the first end-of-life care in dementia intervention to report an increase in family satisfaction with a reduction in hospital deaths.
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For older people living with a diagnosis of dementia, the experience of living and dying in a care home is inextricably linked.
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We have provided the first definition of palliative care in dementia based on evidence and consensus, a framework to provide guidance for clinical practice, policy and research.
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Information on determinants of place of death can inform public health policy regarding care at the end of life and make resource allocation more efficient.
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The results suggest that it is possible to automatically quantify the task quality of smart home activities and perform limited assessment of the cognitive health of individual if smart home activities are properly chosen and learning algorithms are appropriately trained.
Why it matters
This study used smart home sensors and machine learning to predict activity quality and assess cognitive health in 263 volunteers. It found a statistically significant correlation between direct observation scores and predicted activity quality, but this is a monitoring method, not a treatment or cure.
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Case conferencing provides opportunities to improve care palliative care outcomes for older people with dementia by engaging family and all relevant internal and external health providers in prospective care planning.
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This study has identified the professional, organisational and legal factors that influence advance care planning implementation; professional training should target these specific areas.
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Dementia involves progressive and often remorseless decline in cognition, function, behaviour and care needs.
Why it matters
This article reviews assessment scales used in dementia for cognition, function, behavior, quality of life, depression, carer burden, and overall severity. It is about measurement tools for research and care, not about treating or curing Alzheimer's disease.
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Frontotemporal lobar degeneration (FTLD) describes a spectrum of clinically, pathologically and genetically heterogeneous neurodegenerative disorders of unknown aetiology.
Why it matters
This review covers the epidemiology, pathology, diagnosis and management of frontotemporal lobar degeneration, a leading cause of early-onset dementia. It is a descriptive overview and does not report testing of any treatment, cure or prevention.
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Our results show that regarding end-of-life preferences for patients, there is moderate agreement between patients and their spouses, but limited evidence for projection of spouses' preferences on patients (i.e. spouse making a prediction based on own wishes).
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The Framingham Heart Study, the longest-running prospective epidemiologic study in history, was initiated in 1948 in response to the rising toll of coronary heart disease and hypertension.
Why it matters
This paper reviews how the Framingham Heart Study has contributed to stroke and dementia epidemiologic research over 60 years, including relating midlife and late-life risk factors to later stroke, dementia, and cognitive decline. It is a descriptive review, so it cannot show that any specific treatment would prevent or cure dementia.
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Over the past several years, increasing evidence suggests that the Mediterranean diet has a beneficial influence on several age-related diseases, showing protective effect on health and longevity.
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This is the first prospective study employing validated measures of delirium to identify an association between preexisting obstructive sleep apnea and postoperative delirium.
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We investigated structural brain damage in subjects who had suffered severe and diffuse traumatic brain injury (TBI), and examined its relationship with declarative memory impairment.
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43/100
Qualitative methods of service evaluation facilitated a broader and deeper understanding of a range of perspectives, which, with other components of rapid participatory appraisal, generated potential solutions to improve care.
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Cognitive deficits in older adults attributable to Alzheimer's disease (AD) pathology are featured early on by hippocampal impairment.
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43/100
By integrating behavioral measures and imaging data, previous investigations have explored the relationship between biological markers of aging and cognitive functions.
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Four themes were identified: Making the transition; Competence challenged; 'The long view' and Working together.
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Each year in the United States, approximately 1.7 million people are diagnosed with a traumatic brain injury (TBI), about 75% of which are classified as mild TBIs or concussions.
Why it matters
This paper notes that Alzheimer-like dementia, Parkinsonism, and motor neuron disease are associated with repeated brain trauma. It offers no treatment, cure, or prevention for Alzheimer's disease.
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Dementia is an incurable disease. The most promising advances in treatment include cholinesterase inhibitors and memantine.
Why it matters
Use of anti-dementia drugs increased within each insurance group, but the rate of increase did not differ significantly between groups with different pharmacy benefit limits or no drug coverage. The study found no significant effect of drug coverage generosity on the rate of anti-dementia drug uptake.
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CT may be a viable secondary prevention technique for late-life depression, a group who are at risk of further cognitive decline and progression to dementia.
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We investigated the training effects and transfer effects associated with 2 approaches to cognitive activities (so-called brain training) that might mitigate age-related cognitive decline.
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Seriously ill, older adults in an urban ED have substantial palliative care needs.
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It has been claimed that semantic dementia (SD), the temporal variant of fronto-temporal dementia, is characterized by an across-the-board deficit affecting all types of conceptual knowledge.
Why it matters
In semantic dementia, patients showed differential impairment in processing specific semantic word categories, such as color-related versus form-related words. This is about understanding language deficits in semantic dementia and does not address treating, curing, or preventing Alzheimer's disease.
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Vegetables, unsaturated fats, and a high MeDi score may be beneficial to cognitive function.
Why it matters
High vegetable intake and a high ratio of mono- plus polyunsaturated fats to saturated fats were associated with lower odds of mild cognitive impairment. A high Mediterranean diet score was linked to reduced risk of incident MCI or dementia, but this finding was not statistically significant.
From across this topic
10 of the 7,967 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Menopausal hormone therapy and health outcomes during the intervention and extended poststopping phases of the Women's Health Initiative randomized trials
- The epidemiology of the dementias: an update
- A meta-analysis examining clinical predictors of hippocampal volume in patients with major depressive disorder
- Smart Room Design for Dementia Nursing Home Based on Kano-AHP-QFD Integrated Methodology
- The potential mechanism of postoperative cognitive dysfunction in older people
- Dementia imaging in clinical practice: a European-wide survey of 193 centres and conclusions by the ESNR working group
- Perceived experiences of adults with mild cognitive impairment: a qualitative study
- Cognitive Assessment of Dementia Patients Using Large Language Models
- A randomized, observer-blind, controlled trial of the traditional Chinese medicine Yi-Gan San for improvement of behavioral and psychological symptoms and activities of daily living in dementia patients
- End-of-life and Palliative Care in Dementia: An Overview for Clinicians