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lewy
1,022 studies tagged lewy, dated 1967-05-01 to 2026-09-22. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- The value of a family history to distinguish monogenic from polygenic amyotrophic lateral sclerosis 2026-09-22
- Smartphone Passive Digital Phenotyping in Frontotemporal Lobar Degeneration 2026-09-21
- Diagnostic Value of Large Language Model-Extracted Gross Brain Findings in Neurodegenerative Diseases 2026-09-14
Studies
1,022 studies carry this tag.
Date range
1967 to 2026
Top journals
- Neurology 106
- Brain : a journal of neurology 71
- Movement disorders : official journal of the Movement Disorder Society 53
- Annals of neurology 34
- The Lancet. Neurology 34
313 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Dementia is a defining feature of Lewy body disease: its timing and onset distinguish different clinical diagnoses, and its effect on quality of life is profound.
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Our study reveals that PS in DLB is associated with specific deficits in attention and visuospatial/executive function, alongside more severe neuropsychiatric symptoms.
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DLB is characterized by DMN and visual network dysfunction, disrupted local neural activity, and impaired global network integration.
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Frontotemporal lobar degeneration (FTLD) represents a heterogeneous group of neurodegenerative disorders with overlapping clinical, pathological, and genetic characteristics.
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Living in more deprived neighborhoods was associated with an accelerated disease course in bvFTD, highlighting an important socioeconomic disparity in disease prognosis.
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The diagnostic precision of Parkinsonian disorders is not accurate enough.
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Lewy body dementia is the second most common form of neurodegenerative dementia, following Alzheimer's disease.
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Impairments in transactions (47%) and verbal communication (44%) were common at baseline, while impairments in self-care and incontinence ( 40%).
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55/100
BackgroundWhile cortical atrophy has been widely studied in dementia, emerging evidence highlights the role of subcortical degeneration, particularly in deep gray matter structures such as the thalamus, claustrum, and basal nuclei, in both Alzheimer's disease (AD) and frontotemporal dementia (FTD).
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= 0.009). Other neuropathologies were similar across cognitive groups.
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Dopamine transporter (DAT) imaging and electroencephalography (EEG) are recommended biomarkers for diagnosing dementia with Lewy bodies (DLB).
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Two distinct subtypes emerged. Subtype 1 (n = 63) features localized supra-normal gray matter volume deviations in dorsolateral prefrontal regions, elevated free water indicating microstructural disruption, executive dysfunction, and transcriptional enrichment in metabolic dysfunction and neurodegenerative pathways.
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Dementia is a growing problem of global relevance, currently affecting over 55 million people worldwide.
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Previous observational studies demonstrated that lung cancer and both Alzheimer disease (AD) and Parkinson disease (PD) may be related.
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Epidemiological data show that both PD incidence rate and prevalence rate show a significant age-dependent growth trend [3].
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Diagnosis of LBD had high specificity but low sensitivity, with fewer than half of autopsy-confirmed cases having received an LBD diagnosis.
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Symptomatic GRN carriers showed elevated WMHs, primarily in the frontal lobe, while no significant increase was observed in symptomatic C9orf72 or MAPT carriers.
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Frontotemporal dementia (FTD) is the second most common cause of dementia in patients under 65 years, characterized by diverse clinical symptoms, neuropathologies, and genetic background.
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39/100
Frontotemporal dementia (FTD) encompasses a broad, clinically and neuropathologically diverse group of neurodegenerative disorders associated with changes in personality, behaviour, and/or language due to the progressive degeneration of the frontal and temporal lobes of the brain.
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= 0.028). AAS perception stratifies FTD syndromes and constitutes a "real-world audiogram" in these diseases.
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A total of 3828 titles and abstracts and 434 full-text articles were reviewed, yielding 12 articles meeting eligibility criteria.
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DTI-ALPS values were significantly lower compared to HC in both DLB (Estimate = -0.084 [-0.14 to -0.03], p = 0.004) and MCI-LB (Estimate = -0.058 [-0.11 to -0.002], p = 0.047) DTI-ALPS was also significantly associated with both baseline (t[147] = 2.22, p = 0.028) and longitudinal decline (t[127] = 2.41,p = 0.017) in cognitive score.
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Evidence links air pollution to dementia, yet its role in Lewy body dementia (LBD) remains unclear.
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48/100
Dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD) are subtypes of Lewy body dementia, and are considered two ends of a disease spectrum.
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Co-existing neuropathology was frequent, even among individuals without clinical dementia.
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At baseline, sbvFTD showed right-predominant temporal pole involvement associated with significant right frontal atrophy.
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Patients with DLB with anxiety had a significantly higher percentage of fluctuating cognition than those without anxiety.
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FTD subjects exhibited increased plasma levels of gangliosides (GM3(d18:1_16:0), GM3(d18:1_24:1)), ceramide Cer(d18:1_23:0), and select polyunsaturated triacylglycerols.
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Prion diseases are fatal neurological disorders characterized by the accumulation of abnormal proteins in the central nervous system, leading to rapid neurodegeneration.
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Our data show changes in innate immune cells in MCI-LB compared to healthy controls in this small exploratory study.
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We dissociated four key cognitive components underlying remote thinking: spontaneous associative thinking, inhibition of unoriginal responses, intentional remote associative thinking, and verbal initiation; and replicated them in three independent datasets.
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42/100
We observed a nonlinear trajectory of two functional connectivity metrics-temporal variability (fluidity) and connectedness (average node strength)-across symptom severity, especially in the delta frequency band.
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In DLB, plasma concentrations of GFAP and NfL were associated with MTA, GCA-F, and Fazekas scale; and the Aβ42/40 ratio was associated with PA and Fazekas.
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Familial frontotemporal dementia (FTD) is a genetically heterogeneous disease with various clinical manifestations, making it difficult to diagnose.
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Frontotemporal dementia (FTD) refers to a group of neurodegenerative disorders characterized clinically by behavioral disturbances and pathologically by frontal and anterior temporal lobe neurodegeneration, resulting in brain atrophy.
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Lewy body dementia (LBD) is a neurodegenerative disorder characterized by a combination of progressive dementia and spontaneous parkinsonian symptoms.
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Dementia with Lewy bodies (DLB), the second common primary degenerative neurocognitive disorder after Alzheimer disease (AD), frequently presents concurrent co-pathologies that impact clinical presentation and progression.
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Cerebrospinal fluid (CSF) α-synuclein (α-syn) seed amplification assays (SAAs) can detect Lewy body pathology (LBP) with high accuracy but are invasive and costly.
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By combining AI-assisted topic modelling and community engagement, this study aimed to advance the research landscape for Lewy body dementia (LBD).
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Recent work suggests that impairment in emotional processing, along with disinhibition, constitutes the necessary elements for CB in bvFTD.
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30/100
Frequently occurring copathology, most commonly with Alzheimer disease, leads to greater cognitive decline, increased likelihood of admission to a long-term care facility, and a higher risk of mortality.
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A total of 110 patients were identified.
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Glymphatic activity in bvFTD correlated strongly with vascular dysfunction and astrocytic activation, and was associated with brain changes and clinical severity.
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DLB with rapid cognitive decline showed greater CA1 αSYN oligomer burden (p = 0.029) and tau burden (p = 0.029) than DLB with slow decline.
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Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are progressive adult-onset neurodegenerative diseases with overlapping pathological and genetic origins.
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= 0.205; p = 0.651); and between typical (21%) and atypical (11%) subgroups (Fisher's test, p = 0.184).
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Forty bvFTD patients and 40 HC (56.25% female, mean age of 63.55 years) were involved.
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Parkinson's disease (PD), a complex neurodegenerative disorder characterized by selective loss of substantia nigra (SN) dopaminergic neurons, pathological aggregation of α-synuclein (α-syn), and chronic neuroinflammation, is fundamentally driven by redox imbalance and oxidative stress.
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Neurodegenerative diseases (NDs), such as Alzheimer’s disease (AD), Parkinson’s disease (PD) and frontotemporal dementia (FTD), exhibit distinct yet overlapping pathological mechanisms.
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Since the term limbic-predominant age-related TDP-43 encephalopathy (LATE) was coined in 2019, more than 200 articles addressing the subject were published.
From across this tag
9 of the 1,021 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 9. The same 9 appear here every time.
- Alpha-synuclein locus duplication as a cause of familial Parkinson's disease
- Elucidating the Role of Cerebellar Synaptic Dysfunction in C9orf72-ALS/FTD - a Systematic Review and Meta-Analysis
- The ALS/PDC syndrome of Guam and the cycad hypothesis
- MDS clinical diagnostic criteria for Parkinson's disease
- The Lewy body in Parkinson's disease: molecules implicated in the formation and degradation of alpha-synuclein aggregates
- MMSE and MoCA in Parkinson's disease and dementia with Lewy bodies: a multicenter 1-year follow-up study
- Clinical diagnosis of progressive supranuclear palsy: The movement disorder society criteria
- Neuroimaging and plasma biomarker differences and commonalities in Lewy body dementia subtypes
- Epilepsia como manifestación temprana en el espectro de la enfermedad de Alzheimer: explorando la variante epiléptica