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From data to dialogue in setting research priorities for Lewy body dementia
Irina Kinchin, Rachel L. Fitzpatrick, Grigorios Papageorgiou, Joseph P. M. Kane, Panagiotis Alexopoulos, Polychronis Εconomou, Jayne Conlon, Petya Grigorova et al.. npj Dementia, 2025-08-04
Topic: Risk, prevention and care in population studies
Abstract By combining AI-assisted topic modelling and community engagement, this study aimed to advance the research landscape for Lewy body dementia (LBD). Despite being the second most common form of dementia, LBD remains under-recognized and under-researched, with greater care partner burden and poorer quality of life compared to other dementias. A multi-stage prioritization process first employed Latent Dirichlet Allocation to analyse global LBD literature (18,615 abstracts, 2006–2023), revealing an evolution from basic pathogenesis studies to advanced neuroimaging and AI applications post-2017 diagnostic guidelines. The subsequent stages involved consultation with the LBD community in Ireland through surveys, public involvement events, and consensus meetings, which identified crucial gaps in multidisciplinary approaches, prevention strategies, quality of life assessment, and palliative care. The study resulted in fifteen priority areas structured around three pillars: transdisciplinary research, lived experience, and education/information, emphasizing the development of effective diagnostic tools, quality of life frameworks, and treatment approaches.
Key findings
- Despite being the second most common form of dementia, LBD remains under-recognized and under-researched, with greater care partner burden and poorer quality of life compared to other dementias.
Why it matters
This project used AI-assisted analysis of published research plus community consultation to set fifteen research priority areas for Lewy body dementia. It identifies gaps in diagnosis, quality of life and treatment approaches, but does not itself test or provide any treatment, cure or prevention.
Study details
- Evidence strengthLow
How this study scored 32/100
Published in a peer-reviewed journal. Scored zero for study design, sample size, effect reported, studied in people and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (npj Dementia) |
| Journal's citation record | 0 / 4 | Npj Dementia: journal h-index 10 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2025 — within 3 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 1 / 7 | Cited 1 times (OpenAlex, 2026-10-10) |
| Citations per year | 0 / 5 | 0.3 citations a year over 3 year(s) since 2025 |
| Impact for its field and year | 1 / 6 | Cited 0.6× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 0 / 4 | Cited 1 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 2 / 4 | Last-listed author Iracema Leroi: h-index 48 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | Technical University of Munich: institution h-index 1,092 (OpenAlex) |
| Multi-centre collaboration | 2 / 3 | OpenAlex lists 6 institution(s) in 4 countries |
| Indexed in PubMed | 1 / 2 | Not in PubMed, but has a DOI |
| Free to read | 2 / 2 | Free to read |
| Total | 32 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.
APA 7th
Kinchin, I., Fitzpatrick, R. L., Papageorgiou, G., Kane, J. P. M., Alexopoulos, P., Εconomou, P., et al. (2025). From data to dialogue in setting research priorities for Lewy body dementia. npj Dementia. https://doi.org/10.1038/s44400-025-00019-x
Vancouver
Kinchin I, Fitzpatrick RL, Papageorgiou G, Kane JPM, Alexopoulos P, Εconomou P, et al. From data to dialogue in setting research priorities for Lewy body dementia. npj Dementia. 2025. doi:10.1038/s44400-025-00019-x.
BibTeX
@article{kinchin2025-d983627d,
author = {Kinchin, Irina and Fitzpatrick, Rachel L. and Papageorgiou, Grigorios and Kane, Joseph P. M. and Alexopoulos, Panagiotis and Εconomou, Polychronis and Conlon, Jayne and Grigorova, Petya and others},
title = {{From data to dialogue in setting research priorities for Lewy body dementia}},
journal = {npj Dementia},
year = {2025},
doi = {10.1038/s44400-025-00019-x},
url = {https://doi.org/10.1038/s44400-025-00019-x}
}
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Also tagged “bodies”
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