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Newest in this topic

  1. Public awareness of the hearing loss-dementia link and self-reported behavioral changes in middle- to older-aged Canadians 2026-09-26
  2. Patterns of modifiable lifestyle, behavioural and health-related risk factors and their associations with incident dementia in UK Biobank 2026-09-25
  3. Excess hypoglycaemia-related hospitalisation in older adults with comorbid type 2 diabetes and dementia: a UK Biobank cohort study 2026-09-16

Studies

1,139 studies carry this tag.

Date range

1978 to 2026

Top journals

  • Neurology 134
  • Alzheimer s & Dementia 52
  • Alzheimer's & dementia : the journal of the Alzheimer's Association 33
  • Journal of the American Geriatrics Society 32
  • JAMA neurology 27

362 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. The Role of Lifestyle Factors and Sleep Duration for Late-Onset Dementia: A Cohort Study

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Journal of Alzheimer's disease : JAD 2018-01-01 Prevention trials

    This study found no evidence that major lifestyle factors, aside from smoking, or sleep duration influence the risk of dementia.

  2. Association Between Poor Cognitive Functioning and Risk of Incident Parkinsonism: The Rotterdam Study

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. JAMA neurology 2017-12-01 Long-term cohort studies

    Cognitive dysfunction is a common feature among patients with parkinsonism, including Parkinson disease (PD).

  3. Body mass index and risk of dementia: Analysis of individual-level data from 1.3 million individuals

    ✓ Peer-reviewed alzhub usefulness score 73 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2017-11-21 Getting a diagnosis

    The association between BMI and dementia is likely to be attributable to two different processes: a harmful effect of higher BMI, which is observable in long follow-up, and a reverse-causation effect that makes a higher BMI to appear protective when the follow-up is short.

  4. Blood pressure from mid- to late life and risk of incident dementia

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. Neurology 2017-11-08 Risk factors

    Elevated blood pressure during midlife, persistence of elevated blood pressure into late life, and, among nonhypertensives, a steep decline in blood pressure during mid- to late life were associated with an increased dementia risk in a community-based cohort.

  5. Self-rated health and its association with mortality in older adults in China, India and Latin America-a 10/66 Dementia Research Group study

    ✓ Peer-reviewed alzhub usefulness score 61 out of 100. Age and ageing 2017-11-01 Disparities

    However, in many low- and middle-income countries (LMIC) there is a lack of evaluation and the cross-cultural validity of SRH remains largely untested.

  6. Trends in Dementia Incidence in a Birth Cohort Analysis of the Einstein Aging Study

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. JAMA neurology 2017-11-01 Disparities

    Poisson regression was used to model dementia incidence as a function of age, sex, educational level, race, and birth cohort, with profile likelihood used to identify the timing of significant increases or decreases in incidence.

  7. Leisure time physical activity and dementia risk: a dose-response meta-analysis of prospective studies

    ✓ Peer-reviewed alzhub usefulness score 61 out of 100. BMJ open 2017-10-22 Prevention and risk

    We have reported, for the first time, the dose-response relationship between LTPA and dementia, further supporting the international PA guideline from the standpoint of dementia prevention.

  8. Readily Identifiable Risk Factors of Nursing Home Residents' Oral Hygiene: Dementia, Hospice, and Length of Stay

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Journal of the American Geriatrics Society 2017-10-12 End-of-life care

    The findings identify resident subgroups at especially high risk of poor oral health who can be targeted in quality improvement efforts related to oral hygiene; they also indicate need to improve the accuracy of how MDS items are completed.

  9. Associations Between Midlife Vascular Risk Factors and 25-Year Incident Dementia in the Atherosclerosis Risk in Communities (ARIC) Cohort

    ✓ Peer-reviewed alzhub usefulness score 74 out of 100. JAMA neurology 2017-10-01 Prevention and risk

    Midlife vascular risk factors are associated with increased risk of dementia in black and white ARIC Study participants.

  10. Contribution of Socioeconomic Status at 3 Life-Course Periods to Late-Life Memory Function and Decline: Early and Late Predictors of Dementia Risk

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. American journal of epidemiology 2017-10-01 Brain tissue and pathology

    Both early life and adult socioeconomic status (SES) predict late-life level of memory; however, evidence is mixed on the relationship between SES and rate of memory decline.

  11. Metformin vs sulfonylurea use and risk of dementia in US veterans aged ≥65 years with diabetes

    ✓ Peer-reviewed alzhub usefulness score 61 out of 100. Neurology 2017-09-27 Prevention and risk

    Mean age was 73.5 years and mean HbA1c was 6.8%.

  12. Obesity trajectories and risk of dementia: 28 years of follow-up in the Whitehall II Study

    ✓ Peer-reviewed alzhub usefulness score 63 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2017-09-21 Getting a diagnosis

    Obesity (BMI ≥30 kg/m 2 ) at age 50 years (hazard ratio = 1.93; 1.35-2.75) but not at 60 or 70 years was associated with risk of dementia.

  13. Serum magnesium is associated with the risk of dementia

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Neurology 2017-09-20 Long-term cohort studies

    Within the prospective population-based Rotterdam Study, we measured serum magnesium levels in 9,569 participants, free from dementia at baseline (1997-2008).

  14. Affective and emotional dysregulation as pre-dementia risk markers: exploring the mild behavioral impairment symptoms of depression, anxiety, irritability, and euphoria

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. International psychogeriatrics 2017-09-13 Prevention and risk

    Affective symptoms are of prognostic utility, but interventions to prevent dementia syndromes are limited.

  15. Exposure to ambient air pollution and the incidence of dementia: A population-based cohort study

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. Environment international 2017-09-13 Getting a diagnosis

    In this large cohort, exposure to air pollution, even at the relative low levels, was associated with higher dementia incidence.

  16. Association Between Birth in a High Stroke Mortality State, Race, and Risk of Dementia

    ✓ Peer-reviewed alzhub usefulness score 63 out of 100. JAMA neurology 2017-09-01 Disparities

    Overall, birth in an HSMS was associated with a 28% higher risk of dementia (adjusted hazard ratio [aHR], 1.28; 95% CI, 1.13-1.46) adjusted for age, sex, and race.

  17. Sleep architecture and the risk of incident dementia in the community

    ✓ Peer-reviewed alzhub usefulness score 56 out of 100. Neurology 2017-08-23 Long-term cohort studies

    Sleep disturbance is common in dementia, although it is unclear whether differences in sleep architecture precede dementia onset.

  18. Association Between Persistent Pain and Memory Decline and Dementia in a Longitudinal Cohort of Elders

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. JAMA internal medicine 2017-08-01 How common it is

    Persistent pain was associated with accelerated memory decline and increased probability of dementia.

  19. Uric acid and incident dementia over 12 years of follow-up: a population-based cohort study

    ✓ Peer-reviewed alzhub usefulness score 69 out of 100. Annals of the rheumatic diseases 2017-07-28 Hippocampus size on brain scans

    Risk of dementia, especially vascular or mixed dementia, may be increased with high SUA levels in elderly people.

  20. Sleep characteristics and risk of dementia and Alzheimer's disease: The Atherosclerosis Risk in Communities Study

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2017-07-21 Long-term cohort studies

    This study tested the hypotheses that late-midlife obstructive sleep apnea (OSA) and short and long sleep duration are associated with dementia over 15 years of follow-up.

  21. Sleep disturbances increase the risk of dementia: A systematic review and meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 78 out of 100. Sleep medicine reviews 2017-07-06 Prevention and risk

    Sleep disturbances and dementia are two common and significant health problems in older adults.

  22. Trajectories of Depressive Symptoms Before Diagnosis of Dementia: A 28-Year Follow-up Study

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. JAMA psychiatry 2017-07-01 Getting a diagnosis

    Those reporting depressive symptoms in 1985 (mean follow-up, 27 years) did not have significantly increased risk for dementia (hazard ratio [HR], 1.21; 95% CI, 0.95-1.54) in Cox regression adjusted for sociodemographic covariates, health behaviors, and chronic conditions.

  23. Trajectories of Depressive Symptoms Before Diagnosis of Dementia: A 28-Year Follow-up Study

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. JAMA Psychiatry 2017-07 Prevention and risk

    This 28-year study tracked depressive symptoms in over 10,000 people and found that depression appearing later in life (closer to a dementia diagnosis) was linked to higher dementia risk, but depression in midlife (decades before diagnosis) was not.

  24. Physical activity, cognitive decline, and risk of dementia: 28 year follow-up of Whitehall II cohort study

    ✓ Peer-reviewed alzhub usefulness score 73 out of 100. BMJ (Clinical research ed.) 2017-06-22 Getting a diagnosis

    This study found no evidence of a neuroprotective effect of physical activity.

  25. Physical activity, cognitive decline, and risk of dementia: 28 year follow-up of Whitehall II cohort study

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. BMJ 2017-06-22 Prevention and risk

    This unusually long 28-year study found no evidence that being physically active in midlife protects against dementia later in life.

  26. Body mass index in midlife and dementia: Systematic review and meta-regression analysis of 589,649 men and women followed in longitudinal studies

    ✓ Peer-reviewed alzhub usefulness score 72 out of 100. Alzheimer's & dementia (Amsterdam, Netherlands) 2017-06-20 Brain tissue and pathology

    We conducted a meta-analysis of the conflicting epidemiologic evidence on the association between midlife body mass index (BMI) and dementia.

  27. Practical risk score for 5-, 10-, and 20-year prediction of dementia in elderly persons: Framingham Heart Study

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2017-06-13 Long-term cohort studies

    With a rapidly aging population, general practitioners are confronting the challenge of how to determine those who are at greatest risk for dementia and potentially need more specialized follow-up to mitigate symptoms early in its course.

  28. Cerebral Perfusion and the Risk of Dementia: A Population-Based Study

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. Circulation 2017-06-06 Long-term cohort studies

    Cerebral hypoperfusion has previously been associated with mild cognitive impairment and dementia in various cross-sectional studies, but whether hypoperfusion precedes neurodegeneration is unknown.

  29. Central adiposity and the overweight risk paradox in aging: follow-up of 130,473 UK Biobank participants

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. The American journal of clinical nutrition 2017-05-31 Long-term cohort studies

    For older groups, being overweight [body mass index (BMI; in kg/m 2 ): 25 to Objective: This study aimed to estimate associations between combined measurements of BMI and waist-to-hip ratio (WHR) with mortality and incident coronary artery disease (CAD).

  30. Glucose Peaks and the Risk of Dementia and 20-Year Cognitive Decline

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Diabetes care 2017-05-12 Long-term cohort studies

    Hemoglobin A 1c (HbA 1c ), a measure of average blood glucose level, is associated with the risk of dementia and cognitive impairment.

  31. Depression as a modifiable factor to decrease the risk of dementia

    ✓ Peer-reviewed alzhub usefulness score 69 out of 100. Translational psychiatry 2017-05-02 Vascular contributions

    Depression is an accepted risk factor for dementia, but it is unclear if this relationship is causal.

  32. Sugar- and Artificially Sweetened Beverages and the Risks of Incident Stroke and Dementia: A Prospective Cohort Study

    ✓ Peer-reviewed alzhub usefulness score 56 out of 100. Stroke 2017-05-01 Prevention and risk

    Artificially sweetened soft drink consumption was associated with a higher risk of stroke and dementia.

  33. Association Between Midlife Vascular Risk Factors and Estimated Brain Amyloid Deposition

    ✓ Peer-reviewed alzhub usefulness score 75 out of 100. JAMA 2017-04-01 Genetics

    An increasing number of midlife vascular risk factors was significantly associated with elevated amyloid SUVR; this association was not significant for late-life risk factors.

  34. Parental family history of dementia in relation to subclinical brain disease and dementia risk

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Neurology 2017-03-29 Long-term cohort studies

    From 2000 to 2002, we assessed parental history of dementia in participants without dementia of the Rotterdam Study.

  35. Fasting lipid fractions (triglycerides [TGs], high-density lipoprotein cholesterol [HDL-C], low-density lipoprotein cholesterol [LDL-C], total cholesterol [TC]) were studied as continuous variables, and results are reported per SD increase of each lipid fraction.

  36. Intracranial atherosclerosis and dementia: The Atherosclerosis Risk in Communities (ARIC) Study

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Neurology 2017-03-22 Long-term cohort studies

    From 2011 to 2013, 1,744 participants completed high-resolution vessel wall MRI from the population-based Atherosclerosis Risk in Communities Study by a sampling strategy that allowed weighting back to the cohort.

  37. APOE-related risk of mild cognitive impairment and dementia for prevention trials: An analysis of four cohorts

    ✓ Peer-reviewed alzhub usefulness score 63 out of 100. PLoS medicine 2017-03-21 Genetics

    Overall, cumulative incidence was uniformly higher in NACC than in the population-based cohorts.

  38. Hearing loss as a risk factor for dementia: A systematic review

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. Laryngoscope investigative otolaryngology 2017-03-16 Prevention and risk

    Level of evidence Level V, systematic review.

  39. Cerebral microbleeds and risk of incident dementia: the Framingham Heart Study

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Neurobiology of aging 2017-03-06 Long-term cohort studies

    Cerebral microbleeds (CMBs) are MRI markers attributed to the most common cerebral angiopathies in the elderly and in patients with dementia: hypertensive and cerebral amyloid angiopathy.

  40. Defining the Relationship Between Hypertension, Cognitive Decline, and Dementia: a Review

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. Current hypertension reports 2017-03-01 Risk factors

    Hypertension is a highly prevalent condition which has been established as a risk factor for cardiovascular and cerebrovascular disease.

  41. Prolonged sleep duration as a marker of early neurodegeneration predicting incident dementia

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. Neurology 2017-02-22 Long-term cohort studies

    We observed 234 cases of all-cause dementia over 10 years of follow-up.

  42. Living near major roads and the incidence of dementia, Parkinson's disease, and multiple sclerosis: a population-based cohort study

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. The Lancet 2017-02-18 Prevention and risk

    In a study of 2.2 million adults in Ontario, Canada, people who lived very close to a major road (within 50 meters) had a small but statistically significant higher risk of developing dementia than those living farther away (over 300 meters), even after accounting for other health and demographic factors.

  43. Cognitive impairment and dementia: a new emerging complication of type 2 diabetes-The diabetologist's perspective

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Acta diabetologica 2017-02-16 Prevention and risk

    Type 2 diabetes mellitus (T2D) and Alzheimer's disease (AD) are two of the most common diseases of aging around the world.

  44. Pathophysiologic relationship between Alzheimer's disease, cerebrovascular disease, and cardiovascular risk: A review and synthesis

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Alzheimer's & dementia (Amsterdam, Netherlands) 2017-02-09 Prevention and risk

    As the population ages due to demographic trends and gains in life expectancy, the incidence and prevalence of dementia increases, and the need to understand the etiology and pathogenesis of dementia becomes ever more urgent.

  45. Associations between single and multiple cardiometabolic diseases and cognitive abilities in 474 129 UK Biobank participants

    ✓ Peer-reviewed alzhub usefulness score 56 out of 100. European heart journal 2017-02-01 Long-term cohort studies

    Cardiometabolic diseases (hypertension, coronary artery disease [CAD] and diabetes are known to associate with poorer cognitive ability but there are limited data on whether having more than one of these conditions is associated with additive effects.

  46. Living near major roads and the incidence of dementia, Parkinson's disease, and multiple sclerosis: a population-based cohort study

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. Lancet (London, England) 2017-01-05 How common it is

    Between 2001, and 2012, we identified 243 611 incident cases of dementia, 31 577 cases of Parkinson's disease, and 9247 cases of multiple sclerosis.

  47. Late-Life Body Mass Index, Rapid Weight Loss, Apolipoprotein E ε4 and the Risk of Cognitive Decline and Incident Dementia

    ✓ Peer-reviewed alzhub usefulness score 58 out of 100. The journal of nutrition, health & aging 2017-01-01 Long-term cohort studies

    Prospective longitudinal cohort study.

  48. Modifiable Risk Factors for Prevention of Dementia in Midlife, Late Life and the Oldest-Old: Validation of the LIBRA Index

    ✓ Peer-reviewed alzhub usefulness score 56 out of 100. Journal of Alzheimer's disease : JAD 2017-01-01 Prevention and risk

    LIBRA might be a useful tool to identify individuals for primary prevention interventions of dementia in midlife, and maybe in late life, but not in the oldest-old.

  49. Risk Factors Associated with Falls in Older Adults with Dementia: A Systematic Review

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Physiotherapy Canada. Physiotherapie Canada 2017-01-01 Clinical safety

    A total of 17 studies met the inclusion criteria.

  50. Updating the Evidence on the Association between Serum Cholesterol and Risk of Late-Life Dementia: Review and Meta-Analysis

    ✓ Peer-reviewed alzhub usefulness score 73 out of 100. Journal of Alzheimer's disease : JAD 2017-01-01 Brain tissue and pathology

    Cohort studies have reported that midlife high total serum cholesterol (TC) is associated with increased risk of Alzheimer's disease (AD) in late-life but findings have been based on few studies and previous reviews have been limited by a lack of compatible data.

From across this tag

9 of the 1,130 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 9. The same 9 appear here every time.

All topic tags with their study counts