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Newest in this topic

  1. Public awareness of the hearing loss-dementia link and self-reported behavioral changes in middle- to older-aged Canadians 2026-09-26
  2. Patterns of modifiable lifestyle, behavioural and health-related risk factors and their associations with incident dementia in UK Biobank 2026-09-25
  3. Excess hypoglycaemia-related hospitalisation in older adults with comorbid type 2 diabetes and dementia: a UK Biobank cohort study 2026-09-16

Studies

1,139 studies carry this tag.

Date range

1978 to 2026

Top journals

  • Neurology 134
  • Alzheimer s & Dementia 52
  • Alzheimer's & dementia : the journal of the Alzheimer's Association 33
  • Journal of the American Geriatrics Society 32
  • JAMA neurology 27

362 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Vitamin D and the Risk of Dementia: The Rotterdam Study

    ✓ Peer-reviewed alzhub usefulness score 58 out of 100. Journal of Alzheimer's disease : JAD 2017-01-01 Long-term cohort studies

    Vitamin D has gained interest as a potentially modifiable risk factor for dementia because of its putative neuroprotective effects.

  2. Continued Use of Warfarin in Veterans with Atrial Fibrillation After Dementia Diagnosis

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Journal of the American Geriatrics Society 2016-12-30 Health systems and care delivery

    The average CHADS2 score was 3.3 ± 1.3. After a diagnosis of dementia, 405 individuals (16%) persisted on warfarin therapy.

  3. Olfaction and risk of dementia in a biracial cohort of older adults

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Neurology 2016-12-30 Disparities

    Poorer OI in older adults without dementia was associated with increased risk of dementia.

  4. Association of Higher Cortical Amyloid Burden With Loneliness in Cognitively Normal Older Adults

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. JAMA psychiatry 2016-12-01 Caregiving

    Loneliness is a perceived state of social and emotional isolation that has been associated with cognitive and functional decline and an increased risk of incident AD dementia.

  5. Reduced Slow-Wave Sleep Is Associated with High Cerebrospinal Fluid Aβ42 Levels in Cognitively Normal Elderly

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Sleep 2016-11-01 Genetics

    Study objectives Emerging evidence suggests a role for sleep in contributing to the progression of Alzheimer disease (AD).

  6. Environmental risk factors for dementia: a systematic review

    ✓ Peer-reviewed alzhub usefulness score 69 out of 100. BMC geriatrics 2016-10-12 Prevention and risk

    Studies varied widely in size and quality and therefore we must be circumspect in our conclusions.

  7. Orthostatic Hypotension and the Long-Term Risk of Dementia: A Population-Based Study

    ✓ Peer-reviewed alzhub usefulness score 58 out of 100. PLoS medicine 2016-10-11 Long-term cohort studies

    Orthostatic hypotension (OH) is a common cause of transient cerebral hypoperfusion in the population.

  8. Thyroid function and the risk of dementia: The Rotterdam Study

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Neurology 2016-09-16 Long-term cohort studies

    Analyses were performed within the Rotterdam Study (baseline 1997), a prospective, population-based cohort.

  9. Systematic evaluation of the associations between environmental risk factors and dementia: An umbrella review of systematic reviews and meta-analyses

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2016-09-04 Brain tissue and pathology

    Dementia is a heterogeneous neurodegenerative disease, whose etiology results from a complex interplay between environmental and genetic factors.

  10. Polygenic risk of Alzheimer disease is associated with early- and late-life processes

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Neurology 2016-07-06 Genetics

    The influence of this genetic risk may begin in early life and make an individual more susceptible to cognitive impairment in late life.

  11. Trajectories of Depressive Symptoms in Older Adults and Risk of Dementia

    ✓ Peer-reviewed alzhub usefulness score 69 out of 100. JAMA psychiatry 2016-05-01 Disparities

    The analytic cohort included 2488 black and white older adults with repeated depressive symptom assessments from baseline to year 5 who were free of dementia throughout that period.

  12. 10-year trajectories of depressive symptoms and risk of dementia: a population-based study

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. The lancet. Psychiatry 2016-04-29 Long-term cohort studies

    Late-life depressive symptoms have been extensively studied for their relationship with incident dementia, but have been typically assessed at a single timepoint.

  13. Obstructive Sleep Apnea is Linked to Depression and Cognitive Impairment: Evidence and Potential Mechanisms

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2016-04-29 Risk factors

    Obstructive sleep apnea (OSA) is highly prevalent but very frequently undiagnosed.

  14. Dementia risk after spontaneous intracerebral haemorrhage: a prospective cohort study

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. The Lancet. Neurology 2016-04-28 Brain tissue and pathology

    Dementia occurs in at least 10% of patients within 1 year after stroke.

  15. Advanced brain aging: relationship with epidemiologic and genetic risk factors, and overlap with Alzheimer disease atrophy patterns

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Translational psychiatry 2016-04-05 Genetics

    We systematically compared structural imaging patterns of advanced brain aging (ABA) in the general-population, herein defined as significant deviation from typical BA to those found in Alzheimer disease (AD).

  16. Association of Proton Pump Inhibitors With Risk of Dementia: A Pharmacoepidemiological Claims Data Analysis

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. JAMA neurology 2016-04-01 Prevention and risk

    The patients receiving regular PPI medication (n = 2950; mean [SD] age, 83.8 [5.4] years; 77.9% female) had a significantly increased risk of incident dementia compared with the patients not receiving PPI medication (n = 70,729; mean [SD] age, 83.0 [5.6] years; 73.6% female) (hazard ratio, 1.44 [95% CI, 1.36-1.52]; P Conclusions and relevance The avoidance of PPI medication may prevent the development of dementia.

  17. Metabolic Syndrome and the Risk of Mild Cognitive Impairment and Progression to Dementia: Follow-up of the Singapore Longitudinal Ageing Study Cohort

    ✓ Peer-reviewed alzhub usefulness score 65 out of 100. JAMA neurology 2016-04-01 Mild cognitive impairment

    The MetS was associated with an increased incidence of MCI and progression to dementia.

  18. Insomnia and risk of dementia in older adults: Systematic review and meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. Journal of psychiatric research 2016-03-08 Prevention and risk

    There are cross-sectional evidences of an association between sleep disorders and cognitive impairment on older adults.

  19. Nutrition and risk of dementia: overview and methodological issues

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. Annals of the New York Academy of Sciences 2016-03-01 Prevention and risk

    After two decades of research on nutrition and dementia there is strong evidence for preventive effects of vitamin E, B vitamins, and n-3 fatty acids and deleterious effects of saturated fat on dementia.

  20. Behavioural Risk Factors in Mid-Life Associated with Successful Ageing, Disability, Dementia and Frailty in Later Life: A Rapid Systematic Review

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. PloS one 2016-02-04 Prevention and risk

    This search located 10,338 individual references, of which 164 are included in this review.

  21. Incidence of Dementia over Three Decades in the Framingham Heart Study

    ✓ Peer-reviewed alzhub usefulness score 69 out of 100. The New England journal of medicine 2016-02-01 Prevention and risk

    Among participants in the Framingham Heart Study, the incidence of dementia has declined over the course of three decades.

  22. Type 2 Diabetes as a Risk Factor for Dementia in Women Compared With Men: A Pooled Analysis of 2.3 Million People Comprising More Than 100,000 Cases of Dementia

    ✓ Peer-reviewed alzhub usefulness score 76 out of 100. Diabetes Care 2016-02 Prevention and risk

    Pooling data on over 2.3 million people worldwide, this analysis confirmed that type 2 diabetes raises dementia risk by roughly 60% in both men and women, but the excess risk of vascular dementia specifically was notably higher in women than men.

  23. Association of Serum Vitamin D with the Risk of Incident Dementia and Subclinical Indices of Brain Aging: The Framingham Heart Study

    ✓ Peer-reviewed alzhub usefulness score 54 out of 100. Journal of Alzheimer's disease : JAD 2016-01-01 Long-term cohort studies

    Identifying nutrition- and lifestyle-based risk factors for cognitive impairment and dementia may aid future primary prevention efforts.

  24. Associations between Neuropsychiatric Symptoms and Cerebral Amyloid Deposition in Cognitively Impaired Elderly People

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. Journal of Alzheimer's disease : JAD 2016-01-01 Long-term cohort studies

    Neuropsychiatric symptoms, also known as behavioral and psychological symptoms of dementia (BPSD), affect the majority of patients with dementia, and result in a greater cognitive and functional impairment.

  25. Geographical Variation in Dementia Mortality in Italy, New Zealand, and Chile: The Impact of Latitude, Vitamin D, and Air Pollution

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Dementia and Geriatric Cognitive Disorders 2016-01-01 Risk factors

    Dementia SMRs were higher in northern than central or southern Italy.

  26. Incidence of Dementia over Three Decades in the Framingham Heart Study

    ✓ Peer-reviewed alzhub usefulness score 68 out of 100. New England Journal of Medicine 2016 How common it is

    This long-running Massachusetts study tracked dementia rates over more than 30 years and found that a given person's chance of developing dementia at a given age has been steadily falling since the late 1970s. The decline was seen mainly in people with at least a high school education.

  27. Mild Cognitive Impairment and Dementia Prevalence: The Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS)

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Alzheimer's & dementia (Amsterdam, Netherlands) 2016-01-01 How common it is

    MCI and dementia were common among survivors from the original ARIC cohort.

  28. Mild cognitive impairment and dementia prevalence: The Atherosclerosis Risk in Communities Neurocognitive Study

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring 2016 How common it is

    MCI and dementia were common among survivors from the original ARIC cohort.

  29. The risk of overweight/obesity in mid-life and late life for the development of dementia: a systematic review and meta-analysis of longitudinal studies

    ✓ Peer-reviewed alzhub usefulness score 65 out of 100. Age and ageing 2016-01-01 Getting a diagnosis

    Scope it has been suggested that overweight/obesity as a risk factor for incident dementia differs between mid-life and later life.

  30. Depressive symptoms increase the risk of progression to dementia in subjects with mild cognitive impairment: systematic review and meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. International journal of geriatric psychiatry 2015-12-17 Prevention and risk

    Our results provide additional evidence that depressive symptoms determine an additive risk effect to the progression to dementia in subjects with MCI.

  31. Study-level data from 14 studies, 2,310,330 individuals, and 102,174 dementia case patients were included.

  32. Cerebral Vasoreactivity, Apolipoprotein E, and the Risk of Dementia: A Population-Based Study

    ✓ Peer-reviewed alzhub usefulness score 58 out of 100. Arteriosclerosis, thrombosis, and vascular biology 2015-11-19 Long-term cohort studies

    Cerebral vasoreactivity (CVR) is a key factor in maintenance of continuous cerebral perfusion and a marker of (micro)vascular damage.

  33. Dietary Patterns and Risk of Dementia: a Systematic Review and Meta-Analysis of Cohort Studies

    ✓ Peer-reviewed alzhub usefulness score 65 out of 100. Molecular neurobiology 2015-11-09 Prevention and risk

    Dietary patterns and some dietary components have been linked with dementia.

  34. Association Between Atrial Fibrillation and Dementia in the General Population

    ✓ Peer-reviewed alzhub usefulness score 65 out of 100. JAMA neurology 2015-11-01 Long-term cohort studies

    Atrial fibrillation (AF) has been suggested as a risk factor for dementia since it may lead to chronic cerebral hypoperfusion and stroke.

  35. Social activity, cognitive decline and dementia risk: a 20-year prospective cohort study

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. BMC public health 2015-10-24 Prevention and risk

    We observed a complex series of relationships between social-environment variables and cognitive decline and dementia.

  36. Association of Insulin Resistance With Cerebral Glucose Uptake in Late Middle-Aged Adults at Risk for Alzheimer Disease

    ✓ Peer-reviewed alzhub usefulness score 63 out of 100. JAMA neurology 2015-09-01 Brain tissue and pathology

    Patients with AD and individuals at risk for AD show reduced glucose metabolism, as indexed by fludeoxyglucose F 18-labeled positron emission tomography (FDG-PET).

  37. Traffic-Related Air Pollution and Dementia Incidence in Northern Sweden: A Longitudinal Study

    ✓ Peer-reviewed alzhub usefulness score 69 out of 100. Environmental health perspectives 2015-07-31 Risk factors

    If the associations we observed are causal, then air pollution from traffic might be an important risk factor for vascular dementia and Alzheimer's disease.

  38. Mixed pathology is more likely in black than white decedents with Alzheimer dementia

    ✓ Peer-reviewed alzhub usefulness score 65 out of 100. Neurology 2015-07-15 Caregiving

    Black decedents with AD dementia are more likely to have mixed brain pathologies compared with age-, sex-, education-, and cognition-matched white decedents with AD dementia.

  39. Multiple pathologies are common and related to dementia in the oldest-old: The 90+ Study

    ✓ Peer-reviewed alzhub usefulness score 68 out of 100. Neurology 2015-07-15 Caregiving

    In the oldest-old, the presence of multiple pathologies is associated with increased likelihood and severity of dementia.

  40. Gender differences in risk factors for transition from mild cognitive impairment to Alzheimer's disease: A CREDOS study

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Comprehensive psychiatry 2015-07-09 Mild cognitive impairment

    Risk factors for progression from MCI to probable AD differed in men and women.

  41. Sleep duration, cognitive decline, and dementia risk in older women

    ✓ Peer-reviewed alzhub usefulness score 68 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2015-06-15 Prevention and risk

    In older women, habitual sleep duration predicts the future risk for cognitive impairments including dementia, independent of vascular risk factors.

  42. Relationship Between Type 2 Diabetes Mellitus and Cognitive Change in a Multiethnic Elderly Cohort

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Journal of the American Geriatrics Society 2015-06-11 Disparities

    The rate of cognitive change in elderly persons with and without diabetes mellitus is similar, although cognitive performance is poorer in persons with diabetes mellitus.

  43. Social relationships and risk of dementia: A systematic review and meta-analysis of longitudinal cohort studies

    ✓ Peer-reviewed alzhub usefulness score 69 out of 100. Ageing research reviews 2015-05-05 How common it is

    It is unclear to what extent poor social relationships are related to the development of dementia.

  44. Folates and aging: Role in mild cognitive impairment, dementia and depression

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. Ageing research reviews 2015-05-02 Mild cognitive impairment

    In almost all tissues, including the brain, folates are required for one-carbon transfer reactions, which are essential for the synthesis of DNA and RNA nucleotides, the metabolism of amino acids and the occurrence of methylation reactions.

  45. Antipsychotics, other psychotropics, and the risk of death in patients with dementia: number needed to harm

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. JAMA psychiatry 2015-05-01 Getting a diagnosis

    Compared with respective matched nonusers, individuals receiving haloperidol had an increased mortality risk of 3.8% (95% CI, 1.0%-6.6%; P Conclusions and relevance The absolute effect of antipsychotics on mortality in elderly patients with dementia may be higher than previously reported and increases with dose.

  46. The N-terminal pro B-type natriuretic peptide, and risk of dementia and cognitive decline: a 10-year follow-up study in the general population

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. Journal of neurology, neurosurgery, and psychiatry 2015-04-27 Long-term cohort studies

    The N-terminal pro B-type natriuretic peptide (NT-proBNP) has a well-documented prognostic value for cardiovascular disease (CVD) and higher levels are associated with cognitive-dysfunction in patients with CVD.

  47. Genetic risk of neurodegenerative diseases is associated with mild cognitive impairment and conversion to dementia

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2015-04-24 Long-term cohort studies

    Neurodegenerative diseases are a major cause of cognitive impairment and can ultimately lead to dementia.

  48. BMI and risk of dementia in two million people over two decades: a retrospective cohort study

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. The lancet. Diabetes & endocrinology 2015-04-09 How common it is

    Our cohort of 1,958,191 people from UK general practices had a median age at baseline of 55 years (IQR 45-66) and a median follow-up of 9·1 years (IQR 6·3-12·6).

  49. At 48 months, group differences between clinical progressors and non-progressors were significant for self (2.13, SE=0.45, P Conclusions and relevance Demonstrating long-term clinical benefit will be critical for the success of recently launched secondary prevention trials.

  50. Co-morbidity and systemic inflammation as drivers of cognitive decline: new experimental models adopting a broader paradigm in dementia research

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Alzheimer's research & therapy 2015-03-24 Inflammation and the immune system

    Dementia prevalence increases with age and Alzheimer's disease (AD) accounts for up to 75% of cases.

From across this tag

10 of the 1,130 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

All topic tags with their study counts