Home › Research › Topics › disorder
disorder
492 studies tagged disorder, dated 1986-01-01 to 2026-03-31. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Synaptic loss in alcohol use disorder: clinical and mechanistic insights from a PET imaging study 2026-03-31
- Neighborhood environmental deprivation predicts the generalized neurocognitive deficit in schizophrenia 2025-12-19
- Bridging the Gap: Can Hippocampal Sclerosis Serve as a Surrogate Biomarker for LATE‐NC? 2025-12-01
Studies
492 studies carry this tag.
Date range
1986 to 2026
Top journals
- Neurology 38
- Biological psychiatry 36
- NeuroImage 32
- The American journal of psychiatry 22
- Proceedings of the National Academy of Sciences of the United States of America 20
148 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
-
38/100
Alcohol use disorder (AUD) is linked with changes in brain structure and function, with robust evidence for neurodegenerative changes, including synaptic loss in preclinical models.
-
= 0.14. The effect of ADI score was also significant, β = -0.36, t = -2.30, p < .05; while the effect of RUCC, β = 0.06, t = 0.34, p = .73, and the interaction between ADI and RUCC, β = -0.001, t = 0.27, p = .99, were nonsignificant.
-
Among 1,307 individuals, 36.9% were non-White and 49.7% were women.
-
Higher MIND diet scores during the follow-up were associated with fewer reactive microglia (i.e., less neuroinflammation) in the hippocampus when controlled for age at death, sex, education, calories, and AD pathology (β=-0.035, SE=0.02, p = 0.045), but not with total microglia (β=-4.88, SE=3.08, p = 0.114).
-
Only FCSRT-IR LTR rates sufficiently differentiated SCD from HC (AUC of 0.701; 95% CI 0.537-0.865).
-
< 0.1). -ε4 status, and Aβ load, and not mediated by markers of neuroaxonal degradation.
-
Participants' median age was 70.7 years (Q1-Q3 = 67.8-74.0), with 52.4% being women.
-
The mean hippocampal volumes were significantly smaller in the DEM group compared to the MCI and healthy groups (P <0.0001).
-
These results support a functional hippocampal anterior‐posterior differentiation in memory processes and further stress the importance of integrating the dissociation of the hippocampus along its long‐axis concerning functional connectivity in memory processes and dementia.
-
Our findings reveal that specific gut microbial features are closely associated with cognitive impairment and decreased hippocampal volume, which may play an important role in dementia development.
-
Early life adversity impairs normal hippocampal function and connectivity in various mammalian species, including humans and rodents.
-
40/100
Adult brain activities are generally believed to be dominated by chemical and electrical transduction mechanisms.
-
Mild cognitive impairment (MCI) is the prodromal stage of Alzheimer's Disease (AD).
-
49/100
The hippocampus has a well-established role in spatial and episodic memory but a broader function has been proposed including aspects of perception and relational processing.
-
Clinical symptoms correlate with underlying neurodegenerative changes in the vast majority of people.
-
Disrupted hippocampal performance underlies psychiatric comorbidities and cognitive impairments in patients with neurodegenerative disorders.
-
Patients with preserved cognition and mild-verbal memory/semantic fluency were younger (mean [SD] age, 36.5 [9.8] years and 38.2 [11.1] years) and had shorter disease duration (mean [SD] 8.0 [7.3] years and 8.3 [7.6] years) compared with patients with mild-multidomain (mean [SD] age, 42.6 [11.2] years; mean [SD] disease duration, 12.8 [9.6] years; P < .001), severe-executive/attention (mean [SD] age, 42.9 [11.7] years; mean [SD] disease duration, 12.2 [9.5] years; P < .001), and severe-multidomain (mean [SD] age, 44.0 [11.0] years; mean [SD] disease duration, 13.3 [10.2] years; P < .001) phenotypes.
-
Hippocampal volume is a marker of brain health and is reduced with aging and neurological disease.
-
34/100
Proinflammatory cytokine macrophage migration inhibitory factor (MIF) is a multifunctional cytokine and has been found involved in many neurological diseases such as Alzheimer disease (AD), epilepsy, and multiple sclerosis.
-
38/100
Previous research has demonstrated beneficial impact of spermidine intake on memory functions in both animal models and humans, suggesting that spermidine may be a preventive approach to delay age-related cognitive decline and possibly even Alzheimer's disease (AD).
-
Depression and dementia are major public health problems.
-
For cognitively unimpaired individuals, living in the most disadvantaged neighborhoods was associated with significantly lower cerebral volumes, after controlling for maximal premorbid (total intracranial) volume.
-
Medial temporal lobe dependent cognitive functions are highly vulnerable to hypoxia in the hippocampal region, yet little is known about the relationship between the richness of hippocampal vascular supply and cognition.
-
Furthermore, hippocampal subfields susceptible to atrophy in AD were protected by PRT revealing an elimination of long-term atrophy in the left subiculum, and attenuation of atrophy in left CA1 and dentate gyrus when compared to SHAM+SHAM (p = 0.023, p = 0.020 and p = 0.027).
-
This study found that the prevalence of maternal psychological distress in healthy, well-educated, and employed pregnant women was high, underappreciated, and associated with impaired fetal brain biochemistry and hippocampal growth as well as accelerated cortical folding.
-
The progressive decrement of neuropsychological performance is associated with HVL long before the emergence of clinically overt symptoms.
-
62/100
Both AD and TDP/HS contribute to hippocampal volume loss in older-old persons, with TDP/HS more strongly associated with hippocampal volume than AD in Alzheimer dementia.
-
Bipolar disorders were associated with greater, whereas Li treatment with lower discrepancy between brain and chronological age.
-
Measurement of hippocampal volume has proven useful to diagnose and track progression in several brain disorders, most notably in Alzheimer's disease (AD).
-
55/100
Cigarette smoking has been associated with dementia and dementia-related brain changes, notably gray matter (GM) volume atrophy.
-
Hippocampal involvement in MDD is confined to principal substructures only.
-
We found a general trend of increased degree of asymmetry with increasing severity of diagnosis.
-
Predicting the progression of cognitive decline in Alzheimer's disease (AD) is important for treatment selection and patient counseling.
-
The meta-analyses revealed structural brain abnormalities associated with PTSD and trauma and suggest that global brain volume reductions distinguish PTSD from major depression.
-
We observed three stages of activity during both visual picture naming and auditory naming to definition that were serially organized: sensory processing, lexical semantic processing, and articulation.
-
The number of ECT sessions and electrode placement impacts the extent and laterality of hippocampal enlargement, but volume change is not positively associated with clinical outcome.
-
58/100
Total hippocampal volume has been consistently linked to cognitive function and dementia.
-
Early life experience influences stress reactivity and mental health through effects on cognitive-emotional functions that are, in part, linked to gene expression in the dorsal and ventral hippocampus.
-
Accumulating evidence suggests that brain-derived neurotrophic factor (BDNF) is associated with the pathophysiology of major depressive disorder (MDD).
-
The hippocampus is a highly stress susceptible structure and hippocampal abnormalities have been reported in a host of psychiatric disorders including major depression and post-traumatic stress disorder (PTSD).
-
Major Depressive Disorder (MDD) is a common psychiatric disorder for which available medications are often not effective.
-
74/100
Hippocampal volume increase in response to aerobic exercise has been consistently observed in animal models.
-
The monoamine hypothesis has been accepted as the most common hypothesis of major depressive disorder (MDD) for a long period because of its simplicity and understandability.
-
Our study is not subject to the biases of meta-analyses of published data, and it represents an important milestone in an ongoing collaborative effort to examine the neurobiological underpinnings of PTSD and the brain's response to trauma.
-
We aimed to investigate whether hippocampal TDP-43 is associated with increased rates of hippocampal atrophy.
-
PTSD in youth is common and debilitating.
-
The association between gait slowing and cognitive impairment is supported by a shared neural substrate that includes a smaller right hippocampus.
-
The findings suggest that adult neurogenesis is required to maintain hippocampal volume but is not responsible for stress-induced volume loss.
-
In contrast to the idea that hippocampal and amygdala volume loss occur in late phases of neurodegeneration, recent contributions point to the relevance of preexisting structural deficits that are associated with aging and are independent of amyloid deposition in preclinical Alzheimer disease cases.
-
Exercise training is an effective means for promoting white matter and hippocampal recovery and improving reaction time in children treated with cranial radiation for brain tumors.
From across this tag
8 of the 492 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 8. The same 8 appear here every time.
- Hippocampal specialization of food-storing birds
- Hippocampal atrophy in recurrent major depression
- Magnetic resonance imaging of hippocampal and amygdala volume in women with childhood abuse and borderline personality disorder
- Impaired retention of spatial memory after transection of longitudinally oriented axons of hippocampal CA3 pyramidal cells
- 3D PIB and CSF biomarker associations with hippocampal atrophy in ADNI subjects
- Stress abnormalities in individuals at risk for psychosis: a review of studies in subjects with familial risk or with "at risk" mental state
- Hippocampal pathology in refractory temporal lobe epilepsy: T2-weighted signal change reflects dentate gliosis
- MR-based in vivo hippocampal volumetrics: 2. Findings in neuropsychiatric disorders