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disorder
492 studies tagged disorder, dated 1986-01-01 to 2026-03-31. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Synaptic loss in alcohol use disorder: clinical and mechanistic insights from a PET imaging study 2026-03-31
- Neighborhood environmental deprivation predicts the generalized neurocognitive deficit in schizophrenia 2025-12-19
- Bridging the Gap: Can Hippocampal Sclerosis Serve as a Surrogate Biomarker for LATE‐NC? 2025-12-01
Studies
492 studies carry this tag.
Date range
1986 to 2026
Top journals
- Neurology 38
- Biological psychiatry 36
- NeuroImage 32
- The American journal of psychiatry 22
- Proceedings of the National Academy of Sciences of the United States of America 20
148 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Relative to control subjects, patients had significantly smaller HCVs (standardized mean difference = -0.32 [95% confidence interval, -0.44 to -0.19]).
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The hippocampal formation is a brain structure integrally involved in episodic memory, spatial navigation, cognition and stress responsiveness.
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Memory and related cognitive functions are progressively impaired in a subgroup of individuals experiencing childhood adversity and stress.
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Structural magnetic resonance imaging data are frequently analysed to reveal morphological changes of the human brain in dementia.
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These relationships appear to differ between individuals who do and do not develop depression.
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Our findings confirm previous research on the specific roles of CA1 and subiculum in episodic memory.
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We defined superagers (60-80 years old) based on their performance compared to young adults (18-32 years old) on the California Verbal Learning Test Long Delay Free Recall test.
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The hippocampus plays a critical role in verbal and spatial memory, thus any pathological damage to this formation may lead to cognitive impairment.
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Both groups were compared with a sample of healthy control participants (n = 21).
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Building on well-established animal data demonstrating the effects of early maternal support on hippocampal development and adaptive coping, a few longitudinal studies suggest that early caregiver support also impacts human hippocampal development.
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Bilateral vestibulopathy (BVP) is defined as the impairment or loss of function of either the labyrinths or the eighth nerves.
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40/100
White matter deterioration in the aging human brain contributes to cognitive decline.
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This advantage may represent a sex-specific form of cognitive reserve delaying verbal memory decline until more advanced disease stages.
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Shifting policies towards legalisation of cannabis for therapeutic and recreational use raise significant ethical issues for health-care providers seeking evidence-based recommendations.
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Recent findings Anxiety disorders are associated with alterations in fear neurocircuitry such that 'bottom-up' processes in the amygdala which respond to threat are exaggerated, and regulation of these processes by the prefrontal cortex (PFC) and hippocampus is impaired.
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Neuroimaging and postmortem studies of subjects with major depressive disorder (MDD) reveal smaller hippocampal volume with lengthening duration of illness.
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Alterations in learning processes and the neural circuitry that supports fear conditioning and extinction represent mechanisms through which trauma exposure might influence risk for psychopathology.
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The hippocampus has been shown to demonstrate a remarkable degree of plasticity in response to a variety of tasks and experiences.
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Animal models point towards a key role of brain-derived neurotrophic factor (BDNF), insulin-like growth factor-I (IGF-I) and vascular endothelial growth factor (VEGF) in mediating exercise-induced structural and functional changes in the hippocampus.
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Lower intakes of nutrient-dense foods and higher intakes of unhealthy foods are each independently associated with smaller left hippocampal volume.
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Hippocampal atrophy, as evidenced using magnetic resonance imaging (MRI), is one of the most validated, easily accessible and widely used biomarkers of Alzheimer's disease (AD).
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Uncontrollable stress has been recognized to influence the hippocampus at various levels of analysis.
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Hippocampal volume has been shown to be sensitive to variations in estrogen and progesterone levels across rodents' estrous cycle.
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Exposure to elevated levels of PM2.5 was associated with smaller total cerebral brain volume, a marker of age-associated brain atrophy, and with higher odds of covert brain infarcts.
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Automated analysis of MRI data of the subregions of the hippocampus requires computational atlases built at a higher resolution than those that are typically used in current neuroimaging studies.
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Despite the ongoing fundamental controversy about the physiological function of sleep, there is general consensus that sleep benefits neuronal plasticity, which ultimately supports brain function and cognition.
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One of the most replicated findings has been that hippocampus volume is decreased in patients with major depressive disorder (MDD).
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Inflammation and adiposity might relate to cognitive decline via influences on brain morphology.
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The results suggest that longitudinal structural trajectories may differ in major depressive disorder patients according to their clinical response to treatment.
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Serotonin plays an important role in the etiology of depression.
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ECT-induced neuroplasticity in the hippocampus and amygdala relates to improved clinical response and is pronounced in regions with prominent connections to ventromedial prefrontal cortex and other limbic structures.
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Posttraumatic stress disorder (PTSD) is a debilitating condition associated with mild to moderate cognitive impairment and with a prevalence rate of up to 22% in veterans.
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The highly complex structure of the human brain is strongly shaped by genetic influences.
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Key points High frequency (100-250 Hz) neuronal oscillations in the hippocampus, known as sharp-wave ripples (SWRs), synchronise the firing behaviour of groups of neurons and play a key role in memory consolidation.
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Hippocampal atrophy is associated with memory impairment and dementia and serves as a key biomarker in the preclinical stages of Alzheimer's disease.
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62/100
Previous animal models and structural imaging investigations have linked hippocampal neuroplasticity to electroconvulsive therapy (ECT) response, but the relationship between changes in hippocampal volume and temporal coherence in the context of ECT response is unknown.
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Age-related alterations in brain structure and function have been challenging to link to cognition due to potential overlapping influences of multiple neurobiological cascades.
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50/100
We found that longitudinal measures of cortical atrophy were widely correlated with sleep quality.
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67/100
Cardiovascular activity has been shown to be positively associated with gray and white matter volume of, amongst others, frontal and temporal brain regions in older adults.
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We studied with functional magnetic resonance imaging (fMRI) differences in resting-state networks between patients with mesial temporal lobe epilepsy (MTLE) and healthy subjects.
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Alterations in the hippocampus were evident across psychotic disorders.
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Resting-state (RS) functional magnetic resonance (MR) imaging constitutes a novel paradigm that examines spontaneous brain function by using blood oxygen level-dependent contrast in the absence of a task.
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36/100
Reduced hippocampal volumes are probably the most frequently reported structural neuroimaging finding associated with major depressive disorder (MDD).
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The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a collaborative network of researchers working together on a range of large-scale studies that integrate data from 70 institutions worldwide.
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The hippocampus is one of the earliest affected brain regions in Alzheimer's disease (AD) and its dysfunction is believed to underlie the core feature of the disease-memory impairment.
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We compared hippocampal volume measures obtained by manual tracing to automatic segmentation with FreeSurfer in 44 younger (20-30 years) and 47 older (60-70 years) adults, each measured with magnetic resonance imaging (MRI) over three successive time points, separated by four months.
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Hippocampal T2 hyperintensity after FSE represents acute injury often evolving to a radiological appearance of HS after 1 year.
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66/100
A higher omega-3 index was correlated with larger total normal brain volume and hippocampal volume in postmenopausal women measured 8 years later.
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40/100
Our findings support the theory that alterations in hippocampal glutamate levels potentially account for structural deficits in the hippocampus observed in schizophrenia neuroimaging studies.
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Poverty was associated with smaller white and cortical gray matter and hippocampal and amygdala volumes.
From across this tag
8 of the 492 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 8. The same 8 appear here every time.
- Hippocampal volume in first-episode psychoses and chronic schizophrenia: a high-resolution magnetic resonance imaging study
- Multi-modal imaging predicts memory performance in normal aging and cognitive decline
- Frontal-hippocampal double dissociation between normal aging and Alzheimer's disease
- Vulnerability to depression: from brain neuroplasticity to identification of biomarkers
- Thalamic and amygdala-hippocampal volume reductions in first-degree relatives of patients with schizophrenia: an MRI-based morphometric analysis
- A unified approach for morphometric and functional data analysis in young, old, and demented adults using automated atlas-based head size normalization: reliability and validation against manual measurement of total intracranial volume
- Basal Forebrain Volume, but Not Hippocampal Volume, Is a Predictor of Global Cognitive Decline in Patients With Alzheimer's Disease Treated With Cholinesterase Inhibitors
- Decreased hippocampal N-acetylaspartate in the absence of atrophy in posttraumatic stress disorder