Home › Research › Topics › diffusion
diffusion
171 studies tagged diffusion, dated 1981-08-01 to 2026-10-24. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- A digital biomarker of white-matter routing from diffusion MRI as an early biomarker of Alzheimer’s disease 2026-10-24
- Longitudinal associations between neuropsychiatric symptoms, structural and perfusion MRI changes in older adults with Mild Cognitive Impairment 2026-10-19
- Selective vulnerability of human basal forebrain subsystems in ageing and neuropsychiatric disorders 2026-10-15
Studies
171 studies carry this tag.
Date range
1981 to 2026
Top journals
- Brain : a journal of neurology 12
- medRxiv 11
- Alzheimer's & dementia : the journal of the Alzheimer's Association 10
- Neurobiology of aging 10
- NeuroImage 9
79 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
-
Plasma neurofilament light chain (NfL)'s link to dementia may be mediated through white matter integrity (WMI).
-
DNS-br total score and majority of the 11 DNS-br neurocognitive subdomain scores were significantly associated with FDG-PET resilience signature, PIB ratio, cerebral gray matter and white matter volume after adjusting for multiple testing.
-
Early diagnosis of mild cognitive impairment (MCI) fascinates screening high-risk Alzheimer's disease (AD).
-
Despite high correlations (GCA: R2 ≥ 0.85), large overestimation and proportional bias of SUVR relative to DVR was observed.
-
Both objective and perceived social isolations were associated with future cognitive decline and increase risk of Alzheimer's disease (AD).
-
Biomarkers were extracted from a total of 42 participants with longitudinal time points representing 164 imaging volumes.
-
48/100
Regression analyses were run within cohorts to identify variables associated with retrosplenial or inferior parietal FDG standard uptake value ratios.
-
Comparison of SUVR in different brain regions demonstrated significant differences in the temporal, occipital and cerebellar cortices.
-
Our findings demonstrated a significant association between plasma NFL levels and disrupted WM microstructure across the brain.
-
Frontotemporal dementia associated with granulin (GRN) mutations presents asymmetric brain atrophy.
-
50/100
aMCI-HCR compared to aMCI-LCR patients showed significant decrease of CTh in the right temporal and in the left prefrontal lobe.
-
Disrupted iron homeostasis is associated with several neurodegenerative diseases, including Alzheimer's disease (AD), and may be partially modulated by genetic risk factors.
-
57/100
We observed significant differences in the association between CR and white matter tract MTV in aMCI versus HC when age, gender, intracranial volume, and memory ability were held constant.
-
55/100
The purpose of this study was to investigate whether brain and cognitive reserves were associated with the clinical progression of AD dementia.
-
Classification of MCI and HC displayed highest accuracy based on diffusion MRI, which besides demonstrated high correlation with clinical scores.
-
The contribution of cerebellar pathology to cognitive and behavioural manifestations is increasingly recognised, but the cerebellar profiles of FTD phenotypes are relatively poorly characterised.
-
Synaptic disturbances in excitatory to inhibitory (E/I) balance in forebrain circuits are thought to contribute to the progression of Alzheimer's disease (AD) and dementia, although direct evidence for such imbalance in humans is lacking.
-
Neurofilament light chain (NfL) is a marker of brain atrophy and predictor of disease progression in rare diseases such as Huntington Disease, but also in more common neurological disorders such as Alzheimer's disease.
-
52/100
Subjects without amyloid, including three with pathologically confirmed corticobasal degeneration, showed greater regional 18F-AV-1451 retention and associated regional atrophy in areas commonly associated with corticobasal degeneration pathology than healthy control subjects [retention was higher compared to healthy controls (P = 0.0011), driven especially by the precentral gyrus (P = 0.011) and pallidum (P < 0.0001), and greater atrophy was seen in subjects compared to control subjects (P = 0.0004)].
-
Neurofilaments are structural components of neurons and are particularly abundant in highly myelinated axons.
-
Apathy severity was significantly associated with cortical thinning of the lateral parts of the right sided frontal, temporal and parietal lobes.
-
A Brain Chart quantifying brain-aging trajectories was established, enabling the systematic evaluation of individuals' brain-aging patterns relative to this large consortium.
-
Patients with comparable degree of neuropathology could show different cognitive impairments.
-
Posterior cortical atrophy (PCA), considered a visual variant of Alzheimer's disease, has similar pathological characteristics yet shows a selective visual manifestation with relative preservation of other cortical areas, at least at early stages of disease.
-
While aggregation of neuroimaging datasets from multiple sites and scanners can yield increased statistical power, it also presents challenges due to systematic scanner effects.
-
For 50-59 greater medial temporal atrophy and flortaucipir uptake was observed in the typical compared with atypical phenotype.
-
46/100
CR was not associated with hippocampal GM MD and hippocampal GM volume.
-
Numerous imaging variables differed by clinical diagnosis, including hippocampal, amygdalar and inferior lateral ventricular volumes and entorhinal, lingual, inferior parietal and isthmus cingulate cortical thicknesses, at a false discovery rate (FDR)-corrected threshold for significance (analysis of covariance; p < 0.005).
-
Our results indicated that higher global Aβ-SUVR was associated with higher mean diffusivity (MD) in the entire CN group (p = 0.023), and with both higher MD (p = 0.015) and lower fractional anisotropy (FA) (p = 0.026) in APOEɛ4 carriers.
-
Presence on T2-weighted images of white matter hyperintensities (WMH) has been previously shown to be more commonly associated with GRN mutations rather than other forms of FTD.
-
FTP and thickness were differentially related to cognitive performance in several domains.
-
55/100
Elevated baseline plasma NfL is a prognostic marker of cognitive decline and neuroimaging measures of neurodegeneration, and has similar effect sizes to baseline CSF NfL.
-
We found brain volume reduction in the bilateral temporal, amygdala, parahippocampal and lower parietal lobe and left cingulate and precuneus regions (family-wise error, p < 0.05).
-
Dementia is a syndrome characterised by chronic, multi-domain, acquired cognitive impairment that causes significant functional limitations.
-
Preserved executive functioning (EF) is crucial for daily functioning in the elderly and it appears to predict dementia development.
-
Detection of incipient Alzheimer disease (AD) pathophysiology is critical to identify preclinical individuals and target potentially disease-modifying therapies towards them.
-
Cerebrospinal fluid (CSF) neurofilament light (NFL) is a protein biomarker of axonal injury.
-
As our brains age, we tend to experience cognitive decline and are at greater risk of neurodegenerative disease and dementia.
-
An ERICA score of 2 or greater indicates probable AD with high diagnostic accuracy. © RSNA, 2018 Online supplemental material is available for this article.
-
There is increasing evidence showing that brain atrophy varies between patients with Alzheimer's disease (AD), suggesting that different anatomical patterns might exist within the same disorder.
-
Callosal AFD was lower in patients compared to controls.
-
Cognitive reserve (CR) explains interindividual differences in the ability to maintain cognitive function in the presence of neuropathology.
-
The amygdala is composed of multiple nuclei with unique functions and connections in the limbic system and to the rest of the brain.
-
Aging is known to have deleterious effects on cerebral white matter, yet little is known about these white matter alterations in advanced age.
-
This study examined whether cognitive reserve (CR) alters the relationship between magnetic resonance imaging (MRI) measures of cortical thickness and risk of progression from normal cognition to the onset of clinical symptoms associated with mild cognitive impairment (MCI).
-
Activity of the glymphatic system may be evaluated with diffusion images.
-
59/100
There is considerable debate whether Alzheimer's disease (AD) originates in basal forebrain or entorhinal cortex.
-
Genetic and environmental protective factors and risks modulate brain structure and function in neurodegenerative diseases and their preclinical stages.
-
At follow-up, stage 1 subjects showed reduced atrophy rates in medial frontal areas and precuneus compared to stage 0 subjects, whereas stage 2/3 subjects presented accelerated atrophy in medial temporal structures.
-
PSMD is a new, fully automated, and robust imaging marker for SVD.
From across this tag
7 of the 171 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 7. The same 7 appear here every time.
- NODDI: practical in vivo neurite orientation dispersion and density imaging of the human brain
- A surface-based technique for warping three-dimensional images of the brain
- Utility of different MR modalities in mild cognitive impairment and its use as a predictor of conversion to probable dementia
- Associations of plasma neurofilament light chain with cognition and neuroimaging measures in community-dwelling early old age men
- Volume loss of the hippocampus and temporal lobe in healthy elderly persons destined to develop dementia
- Association of white matter hyperintensities with cognitive decline and neurodegeneration
- Longitudinal associations between neuropsychiatric symptoms, structural and perfusion MRI changes in older adults with Mild Cognitive Impairment