Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
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In established dementia, administration of the CogState tasks appears sensitive to cognitive impairment in dementia.
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Our data confirm the retinal involvement in AD, as reflected by loss of axons in the optic nerves.
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The pathological findings of corticobasal degeneration are associated with several distinct clinical syndromes, and the corticobasal syndrome has been linked with a number of diverse pathologies.
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Before any manifestations of cognitive or behavioral changes, there were differences in resting state connectivity in cognitively normal subjects with brain amyloid deposition, suggesting that early manifestation of Abeta toxicity can be detected using resting state fMRI.
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43/100
Amyloid deposition is present in 20-50% of nondemented older adults yet the functional consequences remain unclear.
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Studies of the association of high blood pressure (BP) with dementia are not consistent.
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The TUG, the 6MWT, and gait speed are reliable outcome measures for use with people with AD, recognizing that individual variability of performance is high.
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We present iCluster, a fast and efficient algorithm that clusters a set of images while co-registering them using a parameterized, nonlinear transformation model.
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Recent evidence suggests that some brain areas act as hubs interconnecting distinct, functionally specialized systems.
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A number of factors, including physical activity, may contribute to prevention of cognitive decline and delay the onset of dementia.
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These findings provide further evidence for a specific impairment in frontal-lobe functioning in the preclinical stages of AD in DS.
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Cognitive decline is commonly observed in advanced aging even in the absence of disease.
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Alzheimer's disease (AD) is a neurodegenerative disorder that prominently affects cerebral connectivity.
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In very healthy older adults, performance-based measures better predict early cognitive decline than do subjective measures, and tasks requiring greater functional reserve, such as fast-paced walking, appear to be the most sensitive in assessing these relationships.
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43/100
Given the aging populations in many countries throughout the world, there is an increasing interest in lifestyle factors and interventions that will enhance the cognitive vitality of older adults and reduce the risk for age-related neurological disorders, such as Alzheimer's disease.
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Memory function is likely subserved by multiple distributed neural networks, which are disrupted by the pathophysiological process of Alzheimer's disease (AD).
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Clinical and pathological data from the Rush Memory and Aging Project were used to test the hypothesis that distress proneness is associated with increased risk of Alzheimer's disease (AD).
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We provide a brief review of the literature on exercise effects on brain and cognition.
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The National Adult Reading Test (NART) is widely used as a measure of premorbid IQ of the English-speaking patients with dementia.
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Our study confirms some other studies in showing that in AD patients there is a reduction of parapapillary and macular RNFL thickness and macular volume as measured by OCT.
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A selective distribution of Alzheimer's disease (AD) pathological lesions in specific cortical layers isolates the hippocampus from the rest of the brain.
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In AD, the presence of a lifetime history of depression corresponds to increases in AD-related neuropathological changes within the hippocampus.
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Distinct patterns of brain atrophy exist in CBDS and PSP that can be used to differentiate the 2 diseases.
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Activity and reactivity of the default mode network in the brain was studied using functional magnetic resonance imaging (fMRI) in 28 nondemented individuals with mild cognitive impairment (MCI), 18 patients with mild Alzheimer's disease (AD), and 41 healthy elderly controls (HC).
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It appears that social reasoning is disrupted in a number of ways in fvFTD, and the findings provide a basis for the understanding and further study of abnormal behaviour in this disease.
From across this topic
10 of the 1,533 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Alterations of the pulvinar in posterior cortical atrophy: A multimodal MRI study
- Population based study on patients with traumatic brain injury suggests increased risk of dementia
- A novel computer adaptive word list memory test optimized for remote assessment: Psychometric properties and associations with neurodegenerative biomarkers in older women without dementia
- Regional coherence changes in the early stages of Alzheimer's disease: a combined structural and resting-state functional MRI study
- Default mode network connectivity in patients with idiopathic normal pressure hydrocephalus
- Random forest-based similarity measures for multi-modal classification of Alzheimer's disease
- Associations of inner retinal layers with risk of incident dementia: An individual participant data analysis of four prospective cohort studies
- Is Sleep Disruption a Cause or Consequence of Alzheimer's Disease? Reviewing Its Possible Role as a Biomarker
- Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation
- Environmental risk factors for REM sleep behavior disorder: a multicenter case-control study