Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
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Dementia is a syndrome characterised by the development of multiple cognitive deficits and behavioural changes that significantly interfere with various aspects of life.
Why it matters
This paper discusses ethical challenges around capacity, competence and autonomy in dementia, including healthcare decision-making, financial capacity, driving and voting, and the importance of advance care planning. It is a conceptual overview, not a study of treating, curing or preventing Alzheimer's disease.
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30/100
The basic social process that emerged from the data was that of nurses trying to identify an ACP level and craft a corresponding care plan that they believed would optimise residents' comfort in LTC during both acute medical events and at the end-of-life (EOL).
Why it matters
This study describes long-term-care nurses' experiences of trying to identify an advance care planning level and craft a care plan to optimise residents' comfort. It offers a theoretical model of this process rather than testing whether any intervention changes outcomes.
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This follow-up study builds on our previous research, which showed that combining strategy based cognitive training (ST) with social engagement (SE) improved memory performance in older adults more than social meetings alone.
Why it matters
In this study of 85 older adults, combining strategy-based cognitive training with social engagement led to greater improvements in word recall and verbal fluency than strategy training alone or social engagement alone. This supports including social engagement as a component of cognitive training programs.
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Advance Care Planning (ACP) is a continuous process that enables individuals to discuss and document their preferences for future care in the event of terminal illness or incapacitation.
Why it matters
This analysis of Scottish dementia policies found they inadequately supported the start and review of advance care planning for people with dementia. It does not test any treatment, cure or prevention.
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Most remarkably, research by Cryan and others has shown that transplanting microbes from the guts of people with psychiatric disorders like depression to the guts of rodents can cause comparable symptoms in the animals.CREDIT: JAMES PROVOST (CC BY-ND)Neuroscientist John CryanUniversity College CorkThese effects may occur in several ways — through the vagus nerve connecting the gut to the brain, through the influence of gut bacteria on our immune systems, or by microbes synthesizing molecules that our nerve cells use to communicate.
Why it matters
This article describes research in rodents linking gut microbes to stress, psychiatric symptoms, and brain aging, with cause and effect in humans still unclear. It is early animal work and does not establish any treatment, cure, or prevention for Alzheimer's disease.
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Among Medicare beneficiaries from 2008 to 2018, AD incidence generally decreased while MCI increased.
Why it matters
This study estimated the incidence of Alzheimer's disease and mild cognitive impairment among Medicare beneficiaries, finding that incidence per 10,000 person-years declined for Alzheimer's disease and increased for mild cognitive impairment from 2008 through 2018. Women, older age, White race, and Northeast region were associated with higher incidence of Alzheimer's disease and mild cognitive impairment in 2018.
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Chronic pain is defined as pain that persists or recurs for more than 3 months.
Why it matters
This study correlated lifestyle habits with prevalence of neuropathic pain and fibromyalgia, using dementia-related diseases and Parkinson's disease only as reference conditions. It does not test any treatment, cure, or prevention for Alzheimer's disease.
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Mobile methods, including walking interviews, have rarely been used in research with older adults.
Why it matters
This paper gives advice for researchers on doing walking interviews with older adults, including those with mild cognitive impairment. It is about research methods and does not test any treatment, cure, or prevention for Alzheimer's disease.
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A food desert is a geographic area lacking spatial and socioeconomic access to healthy foods.
Why it matters
This study develops a data-driven food desert metric for Baltimore, not Alzheimer's disease, so it offers nothing on treating, curing or preventing Alzheimer's. It found income level was a key indicator for food desert demarcation.
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The Healthy Brain Initiative: The Public Health Road Map for State and National Partnerships was recently updated for years 2018-2022, which includes recommendations for implementing emergency preparedness (EP) measures at the state and local levels with attention to the unique needs of people living with Alzheimer's disease and other related dementias (ADRD).
Why it matters
This study mapped county-level dementia prevalence in California and found it varied by county along with measures of potential vulnerability. It did not test any treatment, cure, or prevention approach.
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The Richmond Health and Wellness Program (RHWP) provides interprofessional care coordination and wellness services within Richmond’s low income senior housing communities for approximately 1,000 subsidized housing units.
Why it matters
This paper describes a community advisory council in low-income senior housing that identified health themes, including a request for research on cognitive decline. It is about community programming and does not test any treatment, cure, or prevention for Alzheimer's disease.
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As a result, the similarities of older people in residential care to those in nursing care homes greatly outweigh the differences and arguably strengthen the case for RN input to all care home residents.
Why it matters
This commentary states that older people in residential care are very similar to those in nursing care homes. It argues this strengthens the case for registered nurse input to all care home residents.
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Down syndrome (DS) is the most common chromosomal aberration and genetically determined cause of intellectual disability.
Why it matters
This review explains that the chromosome 21 critical region includes the APP gene, leading to excessive amyloid beta production, and that post-mortem Down syndrome brains show diffuse amyloid beta deposits commonly after age 31. It also notes that lipid disturbances, especially in HDL metabolism, are being studied as possible risk factors, but no treatment is tested.
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A targeted HCBS benefit could be added to Medicare and financed with income-related cost sharing ranging from 5% to 50%, a premium paid by Medicare beneficiaries of approximately $42 a month, and payroll taxes estimated at around 0.4% of earnings on employers and employees.
Why it matters
This article discusses financing options for adding a home and community-based services benefit to Medicare for beneficiaries with physical and/or cognitive impairment. It provides no information about treating, curing, or preventing Alzheimer's disease.
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Medicare Help at Home—a proposal to add supplemental home- and community-based services—could be financed by income-related cost-sharing, beneficiary monthly premiums of $42, and an incremental payroll tax on employers and employees of 0.4 percent.
Why it matters
This paper proposes that Medicare Help at Home could be financed by income-related cost-sharing, beneficiary monthly premiums of $42, and an incremental payroll tax on employers and employees of 0.4 percent, producing savings to Medicaid of $1.6 billion over 14 years. An alternative option, an extension of Medicaid Community First Choice, would cost $16,224 per person assisted, with costs offset by reduced nursing home placement.
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The results support the hypothesis that engaging in physical activity can compensate for urban-rural differences in cognitive performance in ageing.
Why it matters
This cross-sectional study found that vigorous weekly physical activity modulated the link between rural or urban residence and global cognition in older Irish adults. It does not test any treatment, cure, or prevention for Alzheimer's disease.
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The 101 CADIS patients demonstrated several new findings: (i) the mean delay between symptom onset and admission was 1.4 days; (ii) for daily attention tests, 5-digit span forward improved to baseline in a mean of 1.3 days, whereas 6-digit span improved in a mean of 5.7 days; (iii) Delirium index, a 7-question instrument for monitoring delirium [2–3] improved to baseline in a mean of 5.8 days.
Why it matters
This report describes timing findings in 101 patients with delirium, including how long daily attention tests and a delirium index took to improve to baseline. It concerns delirium, not Alzheimer's disease, and reports no treatment or prevention effect.
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Down syndrome, or trisomy 21, is the most common chromosomal abnormality associated with intellectual impairment.
Why it matters
This is a forensic review of causes of death in people with Down syndrome, listing Alzheimer disease among many conditions. It does not report on treating, curing, or preventing Alzheimer's disease.
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This thesis developed new Bayesian models to enhance the spatial and temporal resolution of health estimates at the small area level in Australia.
Why it matters
This thesis is about Bayesian small area models for health estimates in Australia, including cancer risk factors, not Alzheimer's disease, so it does not provide information on treating, curing or preventing Alzheimer's. It developed models to improve spatial and temporal resolution of health estimates.
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Our results suggest that in areas like upstate New York, where agricultural land uses are dominant, individual scale factors are the most influential.
Why it matters
This study examined factors affecting parasites of fruit-eating insect larvae in small forest patches. It provides no information on treating, curing or preventing Alzheimer's disease.
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認知症を有する人のためのアドバンス・ケア・プランニング（ACP）では，意思決定能力の揺らぎを前提に，「過去」の意思と「現在」の意向を統合し，非言語的サインも含めて本人の推定意思をくみ取ることが重要である．家族を本人の想いを伝える代弁者として位置づけ，その心理的負担を医療・ケアチームが支える必要がある．また，関係依存性自律を踏まえ，多職種協働で本人中心の対話を継続することが求められる．さらに，想いのかけらを情報通信技術（ICT）等で共有し，ACPを組織的に実施する体制整備が重要である．
Why it matters
This paper discusses how advance care planning should be carried out for people with dementia, including integrating past wishes with current preferences and supporting family members. It is about care planning and communication, not treating, curing or preventing Alzheimer's disease.
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This study examines how users’ preferences for spatial elements in neighborhood parks influence satisfaction and assesses the moderating role of urban density in this relationship.
Why it matters
This study is about neighborhood park features and satisfaction in the Seoul Metropolitan Area, not Alzheimer's disease, so it does not provide information on treating, curing or preventing Alzheimer's. It found that the effects of park spatial elements on user satisfaction varied with urban density.
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In conclusion, while differing in healthcare infrastructure, China, Japan, and South Korea converge in anchoring dementia care within the community.
Why it matters
This work concludes that China, Japan, and South Korea share a focus on anchoring dementia care within the community, despite differing healthcare infrastructure. It addresses policy and care delivery, not the treatment, cure, or prevention of Alzheimer's disease.
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Excess salt intake is one of the relevant dietary determinants of elevated blood pressure and hypertension, with a direct impact on cardiovascular risk.
Why it matters
The paper states that evidence linking sodium intake to cognitive decline is mixed and should be interpreted cautiously, while the strongest evidence concerns blood pressure. It does not show that reducing salt prevents or treats Alzheimer's disease.
From across this topic
10 of the 7,967 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Sensitivity and specificity of the CANTAB Paired Associates Learning test for identifying mild cognitive impairment
- The development of a guidance document for interprofessional collaborative advance care planning in dementia care
- Mediating effect of social support on the relationships between caregiver burden and quality of life in family caregivers of people with dementia: a cross-sectional study in Rural China
- Danggui-Shaoyao-San for dementia: A PRISMA-compliant systematic review and meta-analysis
- Life Course Modifiable Risk Factors of Dementia: Replicating the 2024 Lancet Commission Model in a Single Longitudinal Cohort
- Implications and opportunities regarding biological frameworks in overt and prodromal dementia with Lewy bodies
- Evaluation and management of oropharyngeal dysphagia in different types of dementia: a systematic review
- Investigating three ways of measuring the intrinsic capacity domain of vitality: nutritional status, handgrip strength and ageing biomarkers
- Worsening cognitive impairment and neurodegenerative pathology progressively increase risk for delirium
- The Science of Vascular Contributions to Cognitive Impairment and Dementia (VCID): A Framework for Advancing Research Priorities in the Cerebrovascular Biology of Cognitive Decline